Publications scientifiques sur les diagnostics non invasifs BioPredictive

Études évaluées par les pairs validant les diagnostics sanguins BioPredictive pour les maladies du foie — des cohortes pionnières aux méta-analyses à long terme.

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“Men having sex with men”

“Men having sex with men” Tout effacer
  1. American Association for the Study of the Liver

    Score 100

    FibroTest HCV

  2. HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.

    Steininger K et al. · J Viral Hepat · 2017 Score 99

    …virus(HIV)-infected men who have sex with men (MSM). New direct…

    FibroTest HCV HIV

  3. Clinical and genetic definition of serum bilirubin levels for the diagnosis of Gilbert syndrome and hypobilirubinemia.

    Poynard T et al. · Hepatol Commun · 2023 Score 98

    FibroTest Other

  4. An Invisible Early Steatosis Phenotype Defined for a Large Population-Based Cohort.

    Poynard T et al. · Biomedicines · 2025 Score 97

    …Adjusting for age, sex, SBP, BMI, HbA1c, triglycerides, and high-density lipoprotein…

    FibroTest NashTest-2 SteatoTest-2 Metabolic

  5. Role of genotype G hepatitis B virus mixed infection on the progression of hepatic fibrosis in HIV positive patients over 5 years of follow-up.

    Calin R et al. · J Clin Virol · 2013 Score 96

    …HBV-G infected patients were exclusively from Western Europe with homosexual intercourses…

    FibroTest HBV HIV

  6. Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.

    Dezanet LNC et al. · Liver Int · 2021 Score 95

    …low fibrosis with no progression (29.6%, profile A), low fibrosis with

    FibroTest HBV HIV

  7. Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups.

    Poynard T et al. · Lancet · 1997 Score 94

    …ranging from 13 years in men infected after the age of 40…

    HCV

  8. Prediction for steatosis in type-2 diabetes: clinico-biological markers versus 1H-MR spectroscopy.

    Guiu B et al. · Eur Radiol · 2012 Score 92

    ### Objectives The SteatoTest, fatty liver index (FLI) and hepatic steatosis index (HSI…

    SteatoTest Metabolic

  9. Guidelines for the Screening, Care and Treatment of Persons with Hepatitis C Infection Key publication

    · 2014 Score 91

    These are the first guidelines dealing with hepatitis C treatment produced by…

    FibroTest HCV

  10. Finasteride and methadone use and risk of advanced hepatitis C related liver disease.

    White DL et al. · Dig Dis Sci · 2012 Score 90

    …There were non-significant decreased risks with finasteride use (OR(adj advanced…

    ActiTest FibroTest HCV

  11. Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus.

    Bril F et al. · J Investig Med · 2019 Score 89

    …When the ability of the SteatoTest to identify patients with T2DM with

    ActiTest FibroTest NashTest SteatoTest +1

  12. Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.

    Stevenson M et al. · Health Technol Assess · 2012 Score 88

    …Liver biopsy may be used in patients with suspected ALD to confirm…

    FibroTest Alcohol

  13. Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.

    Khalaf N et al. · Clin Gastroenterol Hepatol · 2015 Score 87

    …against advanced hepatic fibrosis in men with chronic HCV infection. Additional research…

    FibroTest HCV

  14. Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). Key publication

    Poynard T et al. · Diagnostics (Basel) · 2025 Score 85

    …For the first time, obesity was associated with eF before T2D (_p…

    FibroTest-T2D Metabolic

  15. Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.

    Viglino D et al. · Sci Rep · 2018 Score 84

    …In 111 COPD patients, 75% exhibited liver damage with a prevalence of…

    FibroTest NashTest SteatoTest Metabolic

  16. Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.

    Harris R et al. · Lancet Gastroenterol Hepatol · 2017 Score 83

    …Only transient elastography and FibroTest were compared with histological endpoints. The prevalence…

    FibroTest Other

  17. Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication

    Ratziu V et al. · BMC Gastroenterol · 2006 Score 82

    …FT), in patients with NAFLD. ### Methods 170 patients with suspected NAFLD were…

    FibroTest Metabolic

  18. Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication

    Poynard T et al. · BMC Gastroenterol · 2006 Score 81

    …Histological diagnoses used Kleiner et al's scoring system, with 3 classes…

    NashTest Metabolic

  19. Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis. Key publication

    Poynard T et al. · Aliment Pharmacol Ther · 2023 Score 80

    …Biopsy was used as the reference with predetermined cut-offs, advanced fibrosis…

    FibroTest-T2D NashTest-T2D SteatoTest-T2D Metabolic

  20. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.

    Terrault NA et al. · Hepatology · 2018 Score 78

    ActiTest FibroTest HBV

  21. EASL clinical practical guidelines: management of alcoholic liver disease.

    European Association for the Study of Liver · J Hepatol · 2012 Score 77

    FibroTest Alcohol

  22. Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review

    Bril F et al. · Diabetes Care · 2017 Score 76

    …Endocrinologists and those caring for patients with type 2 diabetes mellitus (T2DM…

    FibroTest Metabolic

  23. A simple biological index for detection of alcoholic liver disease in drinkers.

    Poynard T et al. · Gastroenterology · 1991 Score 75

    To make liver biopsy unnecessary in certain cases, PGA (P, prothrombin time…

    Alcohol

  24. The new paradigm of hepatitis C therapy: integration of oral therapies into best practices. Review

    Afdhal NH et al. · J Viral Hepat · 2013 Score 74

    …Coinciding with new treatment options are novel methodologies for disease screening and…

    ActiTest FibroTest HCV

  25. Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).

    Poynard T et al. · BMC Gastroenterol · 2010 Score 73

    …Subjects with presumed advanced fibrosis (FibroTest greater than 0.48) were re…

    FibroTest Alcohol HBV HCV +3

  26. Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.

    Więcek S et al. · Mediators Inflamm · 2020 Score 71

    Changes in the liver and bile ducts observed in patients diagnosed with

    ActiTest FibroTest Other

  27. Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers. Review

    Vilar-Gomez E et al. · J Hepatol · 2018 Score 70

    …In the clinical setting, biomarkers may discriminate between patients with NASH or…

    FibroTest Metabolic

  28. The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.

    Boursier J et al. · Liver Int · 2009 Score 69

    …Three hundred and ninety patients with chronic liver disease of miscellaneous causes…

    FibroTest Alcohol HBV HCV +2

  29. Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.

    Zelber-Sagi S et al. · World J Gastroenterol · 2013 Score 68

    …The FLI was very strongly correlated with SteatoTest (r = 0.91, P…

    SteatoTest Metabolic

  30. Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts. Key publication

    Denimal D et al. · Cardiovasc Diabetol · 2024 Score 67

    …In DIACART, the FibroTest® score was positively correlated with CACS in univariate…

    ActiTest FibroTest NashTest SteatoTest +1

  31. Study of FibroTest and hyaluronic acid biological variation in healthy volunteers and comparison of serum hyaluronic acid biological variation between chronic liver diseases of different etiology and fibrotic stage using confidence intervals.

    Istaces N et al. · Clin Biochem · 2015 Score 66

    …of fibrotic changes in patients with progressive chronic liver disease. Our aim…

    FibroTest HBV HCV

  32. Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.

    Mbaye PS et al. · PLoS One · 2011 Score 64

    …Patients with an LSM range between 7 and 13 kPa underwent liver…

    FibroTest HBV

  33. FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.

    Patel K et al. · World J Gastroenterol · 2011 Score 63

    …disease, with a potential for high diagnostic accuracy in Asians with chronic…

    FibroTest HCV

  34. Efficacy and safety of tenofovir disoproxil fumarate in Asian-Americans with chronic hepatitis B in community settings.

    Pan CQ et al. · PLoS One · 2014 Score 62

    …The percentage of patients with alanine aminotransferase in the normal range increased…

    FibroTest HBV

  35. The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.

    Grigorescu M et al. · J Gastrointestin Liver Dis · 2007 Score 61

    …206 chronic hepatitis C patients with liver biopsy performed before starting antiviral…

    FibroTest HCV

  36. Screening for Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Advanced Fibrosis in Diabetology: A Prospective Multicenter Study.

    Caussy C et al. · Diabetes Care · 2025 Score 60

    …This study aimed to compare the performance of noninvasive tests (NITs) with

    FibroTest Metabolic

  37. Progression of liver fibrosis among injection drug users with chronic hepatitis C.

    Wilson LE et al. · Hepatology · 2006 Score 59

    …Subjects were followed biannually, with a second biopsy offered to those eligible…

    FibroTest

  38. Evaluating the accuracy and increasing the reliable diagnosis rate of blood tests for liver fibrosis in chronic hepatitis C.

    Calès P et al. · Liver Int · 2008 Score 57

    …89.5% with predictive value (PV) and 87.5% with sensitivity/specificity…

    FibroTest HCV

  39. Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases.

    Poinsot P et al. · J Clin Lipidol · 2017 Score 56

    …Children present severe fatty liver disease with early cirrhosis. Before enzyme replacement…

    FibroTest Metabolic

  40. Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.

    Boursier J et al. · Clin Gastroenterol Hepatol · 2023 Score 55

    …We aimed to compare the accuracy of 6 NITs between patients with

    FibroTest Metabolic

  41. Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.

    Bosselut N et al. · Clin Chim Acta · 2013 Score 54

    …The association of Coopscore© with Fibroscan™ increases its predictive value.

    FibroTest HCV

  42. Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.

    Boursier J et al. · Aliment Pharmacol Ther · 2014 Score 53

    …0.751-0.868)] with a significant increase for FIB4: 0.879…

    FibroTest HCV

  43. Prise en charge des personnes infectées par les virus de l’hépatite B ou de l’hépatite C — Rapport de recommandations 2014 Key publication

    Score 52

    FibroTest HBV HCV

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