Scientific publications for BioPredictive non-invasive diagnostics

Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.

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  1. Pilon A, Vaubourdolle M, Peta V, Valla D, Castera L, Bedossa P, Ratziu V, Deckmyn O, Poynard T; the QuidNash Consortium Key publication

    Match 100

    FibroTest Metabolic

  2. Screening studies of transient elastography and FibroTest in the general population.

    Poynard T et al. · Lancet Gastroenterol Hepatol · 2017 Match 99

    FibroTest Other

  3. Screening studies of transient elastography and FibroTest in the general population - Authors' reply.

    Ginès P et al. · Lancet Gastroenterol Hepatol · 2017 Match 97

    FibroTest Other

  4. Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis. Key publication

    Poynard T et al. · Aliment Pharmacol Ther · 2023 Match 95

    …NashTest-T2D was compared to aspartate aminotransferase. SteatoTest-T2D was compared to…

    FibroTest-T2D NashTest-T2D SteatoTest-T2D Metabolic

  5. Performance of Plasma Biomarkers and Diagnostic Panels for Nonalcoholic Steatohepatitis and Advanced Fibrosis in Patients With Type 2 Diabetes.

    Bril F et al. · Diabetes Care · 2020 Match 93

    …Several noninvasive clinical models/scores and plasma biomarkers were measured to identify…

    FibroTest NashTest-2 Metabolic

  6. Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease. Key publication

    Thiele M et al. · Gastroenterology · 2018 Match 92

    …004 for comparison with ELF). Adding a serum marker to transient elastography…

    FibroTest Alcohol

  7. Knowledge and practice regarding the German and the EASL-EASD-EASO NAFLD-guidelines among members of the German Obesity Society.

    Petroff D et al. · Dig Liver Dis · 2018 Match 90

    FibroTest Metabolic

  8. Screening for Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Advanced Fibrosis in Diabetology: A Prospective Multicenter Study.

    Caussy C et al. · Diabetes Care · 2025 Match 88

    …This study aimed to compare the performance of noninvasive tests (NITs) with…

    FibroTest Metabolic

  9. Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). Key publication

    Poynard T et al. · Diagnostics (Basel) · 2025 Match 86

    …We applied 3M to FibroTest-T2D to demonstrate this reduction of uncertainty…

    FibroTest-T2D Metabolic

  10. Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B. Meta Analysis

    Houot M et al. · Aliment Pharmacol Ther · 2016 Match 84

    ### Background Blood tests and transient elastography (TE), proposed as alternatives to biopsy…

    FibroTest HBV HCV

  11. Noninvasive diagnosis in alcohol-related liver disease.

    Hadefi A et al. · Health Sci Rep · 2020 Match 83

    …Among the noninvasive surrogate markers and techniques used to detect liver fibrosis…

    FibroTest Alcohol

  12. Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.

    Chen SH et al. · BMC Gastroenterol · 2012 Match 81

    …This prospective study attempts to identify explanatory factors for LSM in patients…

    FibroTest HCV

  13. Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.

    Schmid P et al. · PLoS One · 2015 Match 79

    ### Objectives To evaluate the diagnostic performance of seven non-invasive tests (NITs…

    FibroTest HCV HIV

  14. Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.

    Fierbinteanu-Braticevici C et al. · World J Gastroenterol · 2009 Match 77

    ### Aim To investigate the diagnostic accuracy of acoustic radiation force impulse (ARFI…

    FibroTest HCV

  15. Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers.

    Friedrich-Rust M et al. · J Thorac Cardiovasc Surg · 2008 Match 75

    …Therefore, early detection of fibrosis is essential to identify patients at risk…

    ActiTest FibroTest Other

  16. Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods. Review

    Festi D et al. · Aliment Pharmacol Ther · 2013 Match 74

    …The articles cited were selected based on their relevancy to the objective…

    SteatoTest

  17. Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.

    Chou R et al. · Ann Intern Med · 2013 Match 72

    ### Background Many blood tests have been proposed as alternatives to liver biopsy…

    FibroTest HCV

  18. Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference. Key publication

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2018 Match 70

    …The combination of 11 parameters permitted to construct a test (NIT-NASHs…

    FibroTest NashTest SteatoTest Metabolic

  19. The non-invasive assessment of hepatic fibrosis. Review

    Gheorghe G et al. · J Formos Med Assoc · 2021 Match 68

    …The liver biopsy with the histopathological examination is considered to be the…

    ActiTest FibroTest Alcohol HBV +2

  20. Non-invasive diagnosis of hepatitis B virus-related cirrhosis. Review

    Lee S et al. · World J Gastroenterol · 2014 Match 67

    …Twenty-three percent of patients with CHB progress naturally to liver cirrhosis…

    FibroTest HBV

  21. Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.

    Stevenson M et al. · Health Technol Assess · 2012 Match 65

    ### Background Excessive alcohol consumption may lead to the development of alcohol-related…

    FibroTest Alcohol

  22. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.

    Terrault NA et al. · Hepatology · 2018 Match 63

    ActiTest FibroTest HBV

  23. Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver.

    Laharie D et al. · Eur J Gastroenterol Hepatol · 2010 Match 61

    ### Background The only way to diagnose nodular regenerative hyperplasia (NRH) is liver…

    FibroTest Other

  24. Noninvasive Markers of Improvement of Liver Steatosis Achieved by Weight Reduction in Patients with Nonalcoholic Fatty Liver Disease.

    Copaci I et al. · Rom J Intern Med · 2015 Match 59

    …The aim of the study was to assess if weight reduction through…

    SteatoTest Metabolic

  25. Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.

    Perazzo H et al. · Aliment Pharmacol Ther · 2014 Match 58

    …mortality and cardiovascular risk. ### Aim To evaluate the prognostic value of non…

    FibroTest SteatoTest Metabolic

  26. EASL clinical practice guidelines: Management of chronic hepatitis B virus infection.

    European Association For The Study Of The Liver · J Hepatol · 2012 Match 56

    ActiTest FibroTest HBV

  27. EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication

    European Association for Study of Liver et al. · J Hepatol · 2015 Match 54

    FibroTest Alcohol HBV HCV +3

  28. Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection

    · 2015 Match 52

    …These recommendations provide opportunities to save lives, improve clinical outcomes of persons…

    FibroTest HBV

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