Scientific publications for BioPredictive non-invasive diagnostics
Peer-reviewed studies validating BioPredictive blood-test diagnostics for liver disease — from first-in-class development cohorts to long-term meta-analyses.
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“Hepatitis B virus (HBV) genotype”
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Role of genotype G hepatitis B virus mixed infection on the progression of hepatic fibrosis in HIV positive patients over 5 years of follow-up.
…Conflicting data surround the role played by genotype-G HBV (HBV-G…
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[Hepatitis B virus genotypes and evolutionary markers in chronic HBsAG patients in Bujumbura].
### Introduction Hepatitis B virus infection (VHB) is a serious condition which can…
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Hepatitis B virus genotype G and liver fibrosis progression in chronic hepatitis B and human immunodeficiency virus coinfection.
### Introduction Infection with hepatitis B virus (HBV) genotype G has been associated…
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Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.
### Introduction Hepatitis C virus (HCV) is the major cause of chronic liver…
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Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali.
### Background Hepatitis B (HB) infection is common in Mali. However, there is…
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EASL Clinical Practice Guidelines: management of hepatitis C virus infection.
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Guidelines for the Screening, Care and Treatment of Persons with Hepatitis C Infection Key publication
These are the first guidelines dealing with hepatitis C treatment produced by…
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Efficacy and safety of tenofovir disoproxil fumarate in Asian-Americans with chronic hepatitis B in community settings.
…The primary efficacy endpoint was hepatitis B virus (HBV) DNA <400 copies…
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Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.
…about its coexistence with chronic hepatitis B (CHB). ### Aims To investigate the…
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
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Real-world efficacy and safety of ombitasvir, paritaprevir/r+dasabuvir+ribavirin in genotype 1b patients with hepatitis C virus cirrhosis.
…2016, approx.5800 patients with virus C cirrhosis received fully reimbursed DAA…
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Non-invasive evaluation of the liver disease severity in children with chronic viral hepatitis using FibroTest and ActiTest - comparison with histopathological assessment.
…hepatitis C virus (HCV), and 1 with hepatitis B virus (HBV)] who…
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Longitudinal assessment of histology surrogate markers (FibroTest-ActiTest) during lamivudine therapy in patients with chronic hepatitis B infection.
…in patients with chronic hepatitis C and B. The aim was to…
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Prise en charge des personnes infectées par les virus de l’hépatite B ou de l’hépatite C — Rapport de recommandations 2014 Key publication
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Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
…LSM in patients with chronic hepatitis B (CHB). One meta-analysis combined…
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Is it possible to predict HCV-related liver cirrhosis non-invasively through routine laboratory parameters? Review
It is estimated that hepatitis C virus (HCV) infects chronically about 160…
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HCV-GenoFibrotest: a combination of viral, liver and genomic (IL28b, ITPA, UGT1A1) biomarkers for predicting treatment response in patients with chronic hepatitis C.
…predictive factors (HCV genotype 2/3, IL28B genotype, FibroTest, ActiTest and viral…
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Discordance between biochemical markers of liver activity and fibrosis (Actitest-Fibrotest) and liver biopsy in patients with chronic hepatitis C.
…the patients had genotype 1 hepatitis C virus infection. Treatment status was…
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EASL clinical practice guidelines: Management of chronic hepatitis B virus infection.
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
…Patients with hepatitis B virus co-infection were excluded. Three hundred and…
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Management of the patient with SVR. Review
…is achievable in ⩾90% of hepatitis C-infected patients. SVR benefits are…
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Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?
…prospective cohort including all hepatitis C virus patients from our institution (N…
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External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV. Key publication
…age, sex, geographical origin, HCV genotype 3, alcohol consumption, and type 2…
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Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.
…human immunodeficiency virus (HIV) and hepatitis B virus (HBV) co-infection during…
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Progression of liver fibrosis among injection drug users with chronic hepatitis C.
Although most hepatitis C virus (HCV) infections are acquired by injection drug…
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Prospective evaluation of FibroTest®, FibroMeter®, and HepaScore® for staging liver fibrosis in chronic hepatitis B: comparison with hepatitis C.
…Optimal cut-offs were consistently lower in hepatitis B compared to hepatitis…
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Role of Non-hepatic Medical Comorbidity and Functional Limitations in Predicting Mortality in Patients with HCV.
### Background Medical comorbidities and functional status limitations are determinants of mortality in…
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Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C.
### Background/Aims In chronic hepatitis C, biopsy is the gold standard for…
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Non-invasive diagnosis and follow-up of chronic infection with Hepatitis C Virus.
Hepatitis C virus (HCV) infection is a major cause of chronic liver…
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Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection
…of persons living with chronic hepatitis B (CHB) infection, and complement similar…
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Higher serum testosterone is associated with increased risk of advanced hepatitis C-related liver disease in males.
…However, the association between testosterone and risk of hepatitis C virus (HCV…
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Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C. Key publication
…biopsy in patients with chronic hepatitis C. The aims of this study…
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Hepatitis C virus viremia and low platelet count: a study in a hepatitis B & C endemic area in Taiwan.
### Background & Aims Hepatitis C virus (HCV) infection has been shown to be…
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The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…In HBV and non-alcoholic steatohepatitis (NASH) patients, its performance was poor…
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Racial differences in the association between adiposity measures and the risk of hepatitis C-related liver disease.
### Background African Americans have lower reported likelihood of hepatitis C virus-related…
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Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.
…Several methods have been proposed in patients with chronic hepatitis C (CHC…
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Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
…LSM in patients with chronic hepatitis C (CHC) using acoustic radiation force…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
…However, in patients chronically infected with hepatitis B virus (HBV), only the…
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Noninvasive assessment of hepatic fibrosis and necroinflammatory activity in Egyptian children with chronic hepatitis C virus infection using FibroTest and ActiTest.
### Background Hepatitis C virus (HCV) is a major cause of chronic hepatitis…
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A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C. Key publication
…the severity of chronic hepatitis C virus (HCV) infection. We compared the…
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Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.
…to hepatitis C virus (HCV) and hepatitis B virus (HBV) treatments, similar…
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Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
…for hepatitis C (63% versus 37% liver biopsy) and hepatitis B (62…
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FibroMAX: towards a new universal biomarker of liver disease? Review
…activity in chronic viral hepatitis C and B; NashTest (BioPredictive) for the…
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Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
…Methods We studied 180 chronic hepatitis C patients. Liver fibrosis was staged…
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Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies. Meta Analysis
…chronic hepatitis C (11 populations) and 772 with chronic hepatitis B (6…
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An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load. Key publication
…status of carriers of chronic hepatitis B. The use of FibroTest (FT…
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The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication
…consecutive patients with chronic hepatitis C and B, alcoholic liver disease, and…
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Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
…virus (HIV)-infected individuals is mostly attributable to co-infection with hepatitis…
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Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.
…markers for liver fibrosis in hepatitis C may improve when combined. Three…
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FibroTest-FibroSURE: towards a universal biomarker of liver fibrosis?
…patients infected with hepatitis B and C virus. These include FibroTest (BioPredictive…
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Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
…different in chronic hepatitis B (CHB) and chronic hepatitis C (CHC). ### Aim…
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Diagnostic value of serum protein profiling by SELDI-TOF ProteinChip compared with a biochemical marker, FibroTest, for the diagnosis of advanced fibrosis in patients with chronic hepatitis C.
…fibrosis in patients with chronic hepatitis C. ### Aim To compare FibroTest with…
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The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
…used for selection of chronic hepatitis C patients eligible for antiviral therapy…
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Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.
### Background & Aims Chronic hepatitis C is both a virologic and fibrotic disease…
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Intra-individual fasting versus postprandial variation of biochemical markers of liver fibrosis (FibroTest) and activity (ActiTest).
…biopsy in patients with chronic hepatitis C and other various chronic liver…
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FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy. Meta Analysis
### Background The accurate diagnosis of hepatitis C virus (HCV)-related fibrosis is…
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Biological markers of liver fibrosis and activity as non-invasive alternatives to liver biopsy in patients with chronic hepatitis C and associated mixed cryoglobulinemia vasculitis.
### Objective And Methods We assessed the reliability of non-invasive biological scoring…
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EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
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Acoustic Radiation Force Impulse Imaging for Diagnosis and Monitoring of Liver Fibrosis in Patients with Hepatitis C: A Review of Diagnostic Accuracy, Clinical Effectiveness, Cost-Effectiveness, and Guidelines Review
…liver fibrosis in patients with hepatitis C. This report represents an update…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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