Pubblicazioni scientifiche sui diagnostici non invasivi BioPredictive
Studi sottoposti a revisione paritaria che convalidano i diagnostici ematici BioPredictive per le malattie del fegato — dalle coorti di sviluppo pionieristiche alle meta-analisi a lungo termine.
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Risultati per
“decompensation of cirrhosis”
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Real-world efficacy and safety of ombitasvir, paritaprevir/r+dasabuvir+ribavirin in genotype 1b patients with hepatitis C virus cirrhosis.
…because of hepatic decompensation (1.9%), 21 stopped because of other adverse…
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Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.
…decompensation, hepatocellular carcinoma (HCC) or liver-related death. ### Results A total of…
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Management of the patient with SVR. Review
In the current era of therapy with direct-acting antiviral (DAAs) drugs…
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Evolution of biomarkers of liver fibrosis and liver insufficiency in hepatitis C virus-infected patients treated with pegylated interferon plus ribavirin and rituximab.
…To date, no study has compared the efficacy of RTX combined with…
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Non-invasive fibrosis tests to predict complications in compensated post-hepatitis C cirrhosis.
### Background And Aims Markers predicting complications of post-hepatitis C cirrhosis are…
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A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C. Key publication
…value of the FibroTest with biopsy staging for predicting cirrhosis decompensation and…
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Hepatocyte-derived biomarkers predict liver-related events at 2 years in Child-Pugh class A alcohol-related cirrhosis.
…Similar results were obtained when using decompensation of cirrhosis, defined according to…
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Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).
…as markers of critical steps defined by occurrence of cirrhosis without complications…
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Noninvasive Assessment of Liver Fibrosis. Key publication Review
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HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.
…Therefore, we aimed to study the course of liver disease after an…
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
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Non-invasive assessment of liver fibrosis: are we ready?
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
### Background And Aim Mortality of alcohol-related liver disease (ArLD) is increasing…
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Non-invasive diagnosis and follow-up of portal hypertension.
…spectrum of advanced fibrosis/cirrhosis in asymptomatic patients at risk of developing…
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Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
Even though alcohol-related liver disease (ALD) is a major cause of…
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Noninvasive diagnosis in alcohol-related liver disease.
### Background Alcohol-related liver disease (ALD) represents a major cause of death…
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Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).
…Despite virological response, the overall incidence of cirrhosis increased, with a remaining…
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Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. Review
…of disorders, ranging from simple steatosis to alcoholic steatohepatitis and cirrhosis. Fatty…
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An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load. Key publication
### Background The combination of transaminases (ALT), biopsy, HBeAg and viral load have…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
### Background & Aim Fibrosis is an independent predictor of death in nonalcoholic steatohepatitis…
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Is it possible to predict HCV-related liver cirrhosis non-invasively through routine laboratory parameters? Review
…1) the presence of cirrhosis has prognostic relevance as it entails a…
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Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
…Optimized cutoffs of ELF to maximize sum of sensitivity and specificity were…
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Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.
…cirrhosis (F = 4), areas under receiver operating characteristic curves (AUROCs) of FT…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
…prognostic value of liver stiffness, non-invasive tests of liver fibrosis, and…
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Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection
…The recommendations in these guidelines promote the use of simple, non-invasive…
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Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
### Objective To determine practices among physicians in Canada for the assessment of…
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis. Review
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
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Guidelines for the Screening, Care and Treatment of Persons with Hepatitis C Infection Key publication
…These guidelines serve as a framework that can allow the expansion of…
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EASL clinical practice guidelines: Management of chronic hepatitis B virus infection.
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Longitudinal assessment of histology surrogate markers (FibroTest-ActiTest) during lamivudine therapy in patients with chronic hepatitis B infection.
…The aim was to use these markers in a prospective study of…
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Non-invasive diagnosis and follow-up of chronic infection with Hepatitis C Virus.
Hepatitis C virus (HCV) infection is a major cause of chronic liver…
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Guidelines for the diagnosis of uncomplicated cirrhosis.
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Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication Review
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication Meta Analysis
FibroTest (FT) is a biomarker of liver fibrosis initially validated in patients…
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Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection. Review
…complications of the end-stage liver disease such as decompensated cirrhosis and…
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Late presentation of chronic viral hepatitis for medical care: a consensus definition.
…the presence of decompensated cirrhosis (at least one symptom of the following…
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The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
…We evaluated the effect of sleeve gastrectomy (SG) on NAFLD using validated…
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Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.
…Forty-four per cent of patients had cirrhosis. Sustained virological response 12…
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Validation of Ten Noninvasive Diagnostic Models for Prediction of Liver Fibrosis in Patients with Chronic Hepatitis B.
…However, the sensitivity, specificity and diagnostic accuracy in evaluating liver fibrosis of…
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Changes of non-invasive markers and FibroScan values during HCV treatment.
The recent advent of non-invasive methods for assessment of fibrosis allows…
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Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
…The AUROC for the diagnosis of liver cirrhosis was 0.92 (95…
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Efficacy and safety of tenofovir disoproxil fumarate in Asian-Americans with chronic hepatitis B in community settings.
…The percentage of patients with alanine aminotransferase in the normal range increased…
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Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
…study cohort, prevalence of advanced fibrosis or cirrhosis was low (<10%) without…
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Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
…This review updates the clinical validation of serum biomarkers and LSM in…
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Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy.
…This study assessed the prevalence, characteristics, and outcomes of antiviral therapy in…
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Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
FibroTest has been validated as a biomarker of fibrosis in patients with…
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Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores.
…25). ### Results TE had the best diagnostic accuracy for detection of cirrhosis…
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EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
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Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.
…for fibrosis and the other for cirrhosis, optimises assessment of liver-prognosis.
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Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.
…We identified profiles of liver fibrosis evolution in coinfected patients undergoing tenofovir…
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Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: the fibrovic study--ANRS HC02.
…The AUROC and the rate of well-classified patients were compared to…
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Improved inflammatory activity with peginterferon alfa-2b maintenance therapy in non-cirrhotic prior non-responders: a randomized study.
…In total, 16% of patients receiving PegIFNα-2b and 11% of observation…
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[Prognosis assessment of alcoholic liver disease: how and why?]. Review
…Most of those deaths could be prevented by an early diagnosis, which…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV. Review
…infected individuals for the exclusion of cirrhosis, but may be poorly reliable…
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Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
…In patients with chronic liver diseases, level of fibrosis predicts liver-related…
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness. Review
The assessment of the fibrotic evolution of chronic hepatitis has always been…
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Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
### Objectives To evaluate the diagnostic performance of seven non-invasive tests (NITs…
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Noninvasive evaluation of NAFLD. Review
…of NASH. Ultrasonography-based transient elastography can exclude advanced fibrosis and cirrhosis…
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Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.
…Hepatoprotective effects of an average daily intake of 100 mg or more…
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Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
### Background Excessive alcohol consumption may lead to the development of alcohol-related…
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An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
…Since the last consensus conference on the management of chronic hepatitis C…
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EASL Clinical Practice Guidelines: management of hepatitis C virus infection.
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Prise en charge des personnes infectées par les virus de l’hépatite B ou de l’hépatite C — Rapport de recommandations 2014 Key publication
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