Publications scientifiques sur les diagnostics non invasifs BioPredictive

Études évaluées par les pairs validant les diagnostics sanguins BioPredictive pour les maladies du foie — des cohortes pionnières aux méta-analyses à long terme.

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“Serological methods”

“Serological methods” Tout effacer
  1. Predicting significant fibrosis in hepatitis C patients in Luxembourg using serological markers.

    Mossong J et al. · Bull Soc Sci Med Grand Duche Luxemb · 2011 Score 100

    …the diagnostic performance of various serological markers and scores for predicting significant…

    FibroTest HCV

  2. Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.

    López Tórrez SM et al. · Front Nutr · 2024 Score 100

    serological biomarkers in predicting liver fibrosis severity in people with MASLD. ### Methods

    FibroTest Metabolic

  3. Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.

    Corradi F et al. · Dig Liver Dis · 2009 Score 99

    …A total of 56 patients (of which 36 with all clinico-serological

    FibroTest HCV

  4. [The value of noninvasive serological markers in hepatitis B]. Review

    García-Samaniego J et al. · Gastroenterol Hepatol · 2014 Score 98

    Bloodless methods (serological and imaging) for evaluating hepatic fibrosis constitute a good…

    FibroTest HBV

  5. The non-invasive assessment of hepatic fibrosis. Review

    Gheorghe G et al. · J Formos Med Assoc · 2021 Score 98

    …This narrative review presents the non-invasive investigation methods used in the…

    ActiTest FibroTest Alcohol HBV +2

  6. Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.

    Halfon P et al. · Antivir Ther · 2009 Score 97

    serological markers of liver fibrosis in HIV-HCV-coinfected patients. ### Methods We…

    FibroTest HCV HIV

  7. Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.

    Trnačević E et al. · Med Glas (Zenica) · 2021 Score 96

    …clinical usability in clinical practice. Methods In this prospective study, 63 CHC…

    FibroTest HCV

  8. Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.

    Crisan D et al. · Hepat Mon · 2012 Score 96

    …diagnostic accuracy of non-invasive methods for the assessment of liver fibrosis…

    FibroTest HCV

  9. Progression of liver fibrosis among injection drug users with chronic hepatitis C.

    Wilson LE et al. · Hepatology · 2006 Score 95

    …No serological test had predictive value greater than 40% for contemporaneous or…

    FibroTest

  10. Spleen stiffness measurement by transient elastography to diagnose portal hypertension in children.

    Goldschmidt I et al. · J Pediatr Gastroenterol Nutr · 2014 Score 94

    …and parameters of portal hypertension. ### Methods A total of 99 children (62…

    FibroTest Other

  11. Altered serum N-glycomics in chronic hepatitis B patients.

    Gui HL et al. · Liver Int · 2010 Score 94

    …with chronic hepatitis B infection. ### Methods Patients with hepatitis B virus (HBV…

    FibroTest HBV

  12. Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali.

    Traoré F et al. · BMC Infect Dis · 2015 Score 93

    …biochemical characteristics of HB carriers. ### Methods A group of 1466 adult volunteers…

    ActiTest FibroTest HBV

  13. EASL clinical practice guidelines: Management of chronic hepatitis B virus infection.

    European Association For The Study Of The Liver · J Hepatol · 2012 Score 92

    ActiTest FibroTest HBV

  14. Non-invasive evaluation of the liver disease severity in children with chronic viral hepatitis using FibroTest and ActiTest - comparison with histopathological assessment.

    Pokorska-Śpiewak M et al. · Clin Exp Hepatol · 2017 Score 92

    …Further studies on non-invasive methods to evaluate liver disease severity in…

    ActiTest FibroTest HBV HCV

  15. Hepatic and renal end-organ damage in the Fontan circulation: A report from the Australian and New Zealand Fontan Registry.

    Wilson TG et al. · Int J Cardiol · 2018 Score 91

    …associated factors remain poorly defined. ### Methods A total of 152 participants from…

    FibroTest Other

  16. Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.

    Dezanet LNC et al. · Liver Int · 2021 Score 90

    …coinfected patients undergoing tenofovir (TDF). ### Methods We included 169 HIV-HBV-coinfected…

    FibroTest HBV HIV

  17. Higher serum testosterone is associated with increased risk of advanced hepatitis C-related liver disease in males.

    White DL et al. · Hepatology · 2012 Score 90

    …g., body mass index), and serological tests (e.g., viral load). The…

    ActiTest FibroTest HCV

  18. A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation. Review

    Ahmad W et al. · Virol J · 2011 Score 89

    …Different invasive and non invasive methods are applied to diagnose the disease…

    FibroTest HCV

  19. Serum bile acid levels as a predictor for the severity of liver fibrosis in patients with chronic hepatitis C.

    Shlomai A et al. · J Viral Hepat · 2013 Score 88

    Serum bile acids (SBAs) are commonly elevated in cholestatic liver diseases, but…

    FibroTest HCV

  20. Guidelines for the Screening, Care and Treatment of Persons with Hepatitis C Infection Key publication

    · 2014 Score 88

    These are the first guidelines dealing with hepatitis C treatment produced by…

    FibroTest HCV

  21. Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.

    Fierbinteanu-Braticevici C et al. · World J Gastroenterol · 2009 Score 87

    …chronic hepatitis C (CHC) patients. ### Methods We performed a prospective blind comparison…

    FibroTest HCV

  22. Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.

    Stibbe KJ et al. · Scand J Gastroenterol · 2011 Score 86

    …in liver biopsy. ### Material And Methods Galactose and methacetin breath tests (GBT…

    FibroTest HBV HCV

  23. Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.

    Gangadharan B et al. · PLoS One · 2012 Score 86

    …Therefore suitable serological biomarkers of liver fibrosis are urgently needed. We used…

    FibroTest HCV

  24. Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients.

    Myers RP et al. · AIDS · 2003 Score 85

    …for markers of liver fibrosis. ### Methods An index incorporating age, sex, alpha…

    FibroTest HCV HIV

  25. Comparison of FibroTest-ActiTest with histopathology in demonstrating fibrosis and necroinflammatory activity in chronic hepatitis B and C.

    Uyar C et al. · Indian J Pathol Microbiol · 2010 Score 84

    …to liver biopsy. ### Materials And Methods Fifty patients were included in the…

    ActiTest FibroTest HBV HCV

  26. Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers. Review

    Vilar-Gomez E et al. · J Hepatol · 2018 Score 84

    The correct identification of patients at increased risk of non-alcoholic steatohepatitis…

    FibroTest Metabolic

  27. PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.

    Petit JM et al. · Liver Int · 2011 Score 83

    ### Context Recently, it has been shown that an allele in the adiponutrin…

    FibroTest Metabolic

  28. Comparison of liver stiffness, fibrotest and liver biopsy for assessment of liver fibrosis in kidney-transplant patients with chronic viral hepatitis.

    Alric L et al. · Transpl Int · 2009 Score 82

    To assess the accuracy of the noninvasive tools, fibrotest (FT) and liver…

    FibroTest HBV HCV

  29. Correlation between liver biopsy and fibrotest in the evaluation of hepatic fibrosis in patients with chronic hepatitis C.

    Said Y et al. · Tunis Med · 2010 Score 82

    …patients with chronic hepatitis C. ### Methods This prospective study included in 2…

    FibroTest HCV

  30. Finasteride and methadone use and risk of advanced hepatitis C related liver disease.

    White DL et al. · Dig Dis Sci · 2012 Score 81

    …hepatitis C virus (HCV) infection. ### Methods In a cross-sectional study in…

    ActiTest FibroTest HCV

  31. Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.

    Kucharska M et al. · Pol Arch Intern Med · 2017 Score 80

    …Noninvasive methods such as shear wave elastography and FibroTest may allow a…

    FibroTest HCV

  32. Study on noninvasive laboratory tests for fibrosis in chronic HBV infection and their evaluation.

    Chen J et al. · J Clin Lab Anal · 2013 Score 80

    …B (CHB) related liver fibrosis. ### Methods A JETLIA-962 chemiluminescence analyzer was…

    FibroTest HBV

  33. The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.

    Grigorescu M et al. · J Gastrointestin Liver Dis · 2007 Score 79

    …for antiviral therapy. ### Patients And Methods A retrospective study was carried out…

    FibroTest HCV

  34. Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.

    Crisan D et al. · Indian J Med Res · 2017 Score 78

    …resistance (IR) and liver histology. ### Methods Two hundred and three consecutive biopsy…

    ActiTest FibroTest SteatoTest HCV

  35. Biochemical markers of liver fibrosis: a comparison with historical features in patients with chronic hepatitis C.

    Myers RP et al. · Am J Gastroenterol · 2002 Score 78

    …the prediction of significant fibrosis. ### Methods Untreated patients with chronic hepatitis C…

    FibroTest HCV

  36. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.

    Terrault NA et al. · Hepatology · 2018 Score 77

    ActiTest FibroTest HBV

  37. Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C.

    Sebastiani G et al. · J Hepatol · 2006 Score 76

    …combining them in sequential algorithms. ### Methods One hundred and ninety patients with…

    FibroTest HCV

  38. Prevalence of liver cirrhosis in individuals with hepatitis B virus infection in sub-Saharan Africa: Systematic review and meta-analysis. Meta Analysis

    Surial B et al. · Liver Int · 2021 Score 75

    …chronic HBV infection in SSA. ### Methods We performed a systematic review of…

    FibroTest HBV

  39. Liver fibrosis in young Egyptian beta-thalassemia major patients: relation to hepatitis C virus and compliance with chelation.

    Elalfy MS et al. · Ann Hepatol · 2013 Score 75

    …Non invasive Liver FibroScan and Fibro-Test were reliable methods to assess…

    ActiTest FibroTest HCV

  40. Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.

    Myers RP et al. · Dig Dis Sci · 2003 Score 74

    As an alternative to liver biopsy, an index of five biochemical markers…

    FibroTest HCV

  41. Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.

    Park MS et al. · Liver Int · 2015 Score 73

    …with chronic hepatitis B (CHB). ### Methods Consecutive patients with CHB who underwent…

    FibroTest HBV

  42. Liver stiffness measurement in children using FibroScan: feasibility study and comparison with Fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy.

    de Lédinghen V et al. · J Pediatr Gastroenterol Nutr · 2007 Score 73

    …chronic liver diseases. ### Patients And Methods Between February 2004 and October 2005…

    FibroTest HBV HCV Other

  43. Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.

    Adams LA et al. · J Gastroenterol Hepatol · 2011 Score 72

    …a multi-centre NAFLD cohort. ### Methods Simple (APRI, BARD) and complex (Hepascore…

    FibroTest Metabolic

  44. Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.

    Friedrich-Rust M et al. · BMC Gastroenterol · 2010 Score 71

    …direct comparison of both markers. ### Methods In the present study, the ELF…

    FibroTest HBV HCV Other

  45. Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.

    Friedrich-Rust M et al. · Ultraschall Med · 2009 Score 71

    …the FibroTest (FT) are established methods for the noninvasive staging of liver…

    FibroTest Alcohol HBV HCV +2

  46. Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Key publication

    Imbert-Bismut F et al. · Lancet · 2001 Score 70

    …significant fibrosis (including early stages). ### Methods We assessed liver-biopsy patients with…

    FibroTest HCV

  47. Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases.

    Coco B et al. · J Viral Hepat · 2007 Score 69

    Liver stiffness was measured by transient elastography (FibroScan) in 228 consecutive patients…

    FibroTest Alcohol HBV HCV +1

  48. Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy.

    Anastasiou J et al. · Eur J Gastroenterol Hepatol · 2010 Score 69

    …LB) as the reference standard. ### Methods An unselected and consecutive group of…

    ActiTest FibroTest Alcohol HBV +3

  49. Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.

    Sadler MD et al. · Can J Gastroenterol Hepatol · 2015 Score 68

    …the diagnostic performance of noninvasive methods for the detection of CFLD with…

    FibroTest Other

  50. Prospective noninvasive analysis of hepatic fibrosis in patients with Crohn's disease: correlation of transient elastography and laboratory-based markers.

    Brühl J et al. · Eur J Gastroenterol Hepatol · 2011 Score 67

    …patients with Crohn's disease. ### Methods A total of 114 patients were…

    FibroTest Other

  51. Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.

    Zarski JP et al. · J Hepatol · 2012 Score 67

    …liver biopsy, in untreated patients with chronic hepatitis C (CHC). ### Methods This…

    FibroTest HCV

  52. Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?

    Thabut D et al. · Am J Gastroenterol · 2006 Score 66

    …FT-AT]) in aged patients. ### Methods This was a retrospective study with…

    FibroTest HCV

  53. Performance of 11 biomarkers for liver fibrosis assessment in HIV/HBV co-infected patients.

    Bottero J et al. · J Hepatol · 2009 Score 65

    …in HIV/HBV co-infection. ### Methods Performance was evaluated using the Receiver…

    FibroTest HBV HIV

  54. An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication

    Myers RP et al. · Can J Gastroenterol · 2012 Score 65

    Chronic hepatitis C remains a significant medical and economic burden in Canada…

    FibroTest HCV

  55. Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.

    Sebastiani G et al. · Can J Gastroenterol Hepatol · 2014 Score 64

    …noninvasive methods were mostly used for hepatitis C (63% versus 37% liver…

    FibroTest Alcohol HBV HCV +3

  56. Development and validation of a nomogram based on clinical factors and standard laboratory tests for prediction of clinically significant liver fibrosis in chronic hepatitis C virus infection.

    Sagrini E et al. · Eur J Gastroenterol Hepatol · 2013 Score 63

    …noninvasive fibrosis score. ### Materials And Methods Nomograms are graphical representations of a…

    FibroTest HCV

  57. Personalized management of cirrhosis by non-invasive tests of liver fibrosis. Review

    Wong GL et al. · Clin Mol Hepatol · 2015 Score 63

    Owing to the high prevalence of various chronic liver diseases, cirrhosis is…

    FibroTest Alcohol HBV HCV +1

  58. Non-invasive assessment of liver fibrosis progression in hepatitis C patients retreated for 96 weeks with antiviral therapy: a randomized study.

    Zarski JP et al. · Liver Int · 2010 Score 62

    ### Background The efficacy of a maintenance therapy in non-responder patients with…

    ActiTest FibroTest HCV

  59. Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. Review

    Lombardi R et al. · World J Gastroenterol · 2015 Score 61

    Alcoholic liver disease (ALD) consists of a broad spectrum of disorders, ranging…

    FibroTest Alcohol

  60. EASL Clinical Practice Guidelines: management of hepatitis C virus infection.

    European Association for the Study of the Liver · J Hepatol · 2011 Score 61

    ActiTest FibroTest HCV

  61. Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV. Review

    Matta B et al. · Curr HIV/AIDS Rep · 2016 Score 60

    …Multiple non-invasive methods of liver fibrosis assessment have been developed, but…

    FibroTest HBV HCV HIV

  62. Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).

    Poynard T et al. · J Hepatol · 2014 Score 59

    …primary liver cancer, variceal bleeding, or decompensation (ascites, encephalopathy, or jaundice). ### Methods

    FibroTest HCV

  63. Management of the patient with SVR. Review

    Terrault NA et al. · J Hepatol · 2016 Score 59

    In the current era of therapy with direct-acting antiviral (DAAs) drugs…

    FibroTest HCV

  64. Longitudinal assessment of histology surrogate markers (FibroTest-ActiTest) during lamivudine therapy in patients with chronic hepatitis B infection.

    Poynard T et al. · Am J Gastroenterol · 2005 Score 58

    …factors associated with fibrosis progression. ### Methods Two hundred and ninety-eight patients…

    ActiTest FibroTest HBV

  65. Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.

    Vergniol J et al. · Gastroenterology · 2011 Score 57

    …All methods were able to predict shorter survival times in this large…

    FibroTest HCV HIV

  66. Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.

    Sebastiani G et al. · Aliment Pharmacol Ther · 2012 Score 57

    …by METAVIR) and cirrhosis (F4). ### Methods A total of 1013 HCV monoinfected…

    FibroTest HCV

  67. Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness. Review

    Stasi C et al. · World J Gastroenterol · 2016 Score 56

    …Over the past decade, various non-invasive methods have been proposed to…

    FibroTest HCV

  68. Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection

    · 2015 Score 55

    These are the first World Health Organization (WHO) guidelines for the prevention…

    FibroTest HBV

  69. Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).

    Poynard T et al. · Diagnostics (Basel) · 2025 Score 55

    …This can be achieved if three essential but neglected STARD methods (3M…

    FibroTest-T2D Metabolic

  70. Liver fibrosis regression and progression during controlled hepatitis B virus infection among HIV-HBV patients treated with tenofovir disoproxil fumarate in France: a prospective cohort study.

    Boyd A et al. · J Int AIDS Soc · 2017 Score 54

    …in TDF-treated coinfected patients. ### Methods In this prospective cohort study, 167…

    FibroTest HBV HIV

  71. An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load. Key publication

    Ngo Y et al. · PLoS One · 2008 Score 53

    …of the inactive carrier status. ### Methods And Findings 1,300 consecutive CHB…

    ActiTest FibroTest HCV

  72. Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes.

    Poynard T et al. · Aliment Pharmacol Ther · 2021 Score 53

    …NASH grades and steatosis grades. ### Methods We prospectively analysed 272 patients with…

    FibroTest NashTest-2 SteatoTest Metabolic

  73. EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication

    European Association for Study of Liver et al. · J Hepatol · 2015 Score 52

    FibroTest Alcohol HBV HCV +3

  74. Ministère des Affaires Sociales et de la Santé Key publication

    Score 51

    FibroTest HBV HCV

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