Pubblicazioni scientifiche sui diagnostici non invasivi BioPredictive
Studi sottoposti a revisione paritaria che convalidano i diagnostici ematici BioPredictive per le malattie del fegato — dalle coorti di sviluppo pionieristiche alle meta-analisi a lungo termine.
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Risultati per
“CHC, chronic HCV”
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Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
…in chronic hepatitis B (CHB) and chronic hepatitis C (CHC). ### Aim To…
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Prospective evaluation of FibroTest®, FibroMeter®, and HepaScore® for staging liver fibrosis in chronic hepatitis B: comparison with hepatitis C.
### Background & Aims Fibrosis blood tests have been validated in chronic hepatitis C…
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Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.
### Unlabelled The association of NAFLD with chronic hepatitis C (CHC) has been…
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Prevalence of liver fibrosis and cirrhosis in 699 Moroccan patients with chronic hepatitis C.
### Introduction chronic hepatitis C (CHC) can cause severe complications, including fibrosis and…
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Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.
…In France 470,762 subjects were investigated (subjects with HCV and other…
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Longitudinal assessment of hepatitis C fibrosis progression by collagen and smooth muscle actin morphometry in comparison to serum markers.
…study cohort included 201 chronic hepatitis C (CHC) nonresponders enrolled in a…
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An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
…of antiviral therapy in chronic hepatitis C (CHC). This study compared two…
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Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.
…C virus (HCV) infection is important cause of chronic hepatitis. Liver biopsy…
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Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.
…transient elastography (TE) in chronic hepatitis C (CHC) patients in order to…
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Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.
…liver-prognosis assessment in chronic hepatitis C (CHC). ### Methods A total of…
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Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.
…of liver fibrosis in chronic hepatitis C (CHC) patients. ### Methods We performed…
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Acoustic Radiation Force Impulse Imaging for Diagnosis and Monitoring of Liver Fibrosis in Patients with Hepatitis C: A Review of Diagnostic Accuracy, Clinical Effectiveness, Cost-Effectiveness, and Guidelines Review
Acoustic Radiation Force Imaging (ARFI) is an emerging non-invasive procedure that…
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Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?
### Background Few data are available on chronic hepatitis C (CHC) in elderly…
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B. Meta Analysis
…reference, in patients with chronic hepatitis C (CHC) or B (CHB). Investigators…
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Contribution of the ELFG test in algorithms of non-invasive markers towards the diagnosis of significant fibrosis in chronic hepatitis C.
…of significant fibrosis in chronic hepatitis C (CHC) patients using all available…
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Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores.
…oesophageal varices (OV) in chronic hepatitis C (CHC), as compared with currently…
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External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV. Key publication
…LCR2 in patients with chronic HCV (CHC) treated or not with antivirals…
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Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.
…a new score in chronic hepatitis C (CHC) by selecting blood markers…
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Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.
…Several methods have been proposed in patients with chronic hepatitis C (CHC…
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Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
### Objective Chronic viral hepatitis B and C cause liver fibrosis, leading to…
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Study of FibroTest and hyaluronic acid biological variation in healthy volunteers and comparison of serum hyaluronic acid biological variation between chronic liver diseases of different etiology and fibrotic stage using confidence intervals.
…changes in patients with progressive chronic liver disease. Our aim was to…
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Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.
…Methods A total of 1013 HCV monoinfected cases undergoing liver biopsy were…
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Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.
…liver biopsy, in untreated patients with chronic hepatitis C (CHC). ### Methods This…
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A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C.
…recommended in patients with chronic hepatitis C (CHC). Blood fibrosis tests and…
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Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
…LSM in patients with chronic hepatitis C (CHC) using acoustic radiation force…
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Evolving practices of non-invasive markers of liver fibrosis in patients with chronic hepatitis C in France: time for new guidelines?
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Performance of noninvasive markers for liver fibrosis is reduced in chronic hepatitis C with normal transaminases.
In chronic hepatitis C, biopsy is the gold standard for assessment of…
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Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.
…to virological response in chronic hepatitis C (CHC) is interferon-gamma-inducible…
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Hepatitis C virus viremia and low platelet count: a study in a hepatitis B & C endemic area in Taiwan.
### Background & Aims Hepatitis C virus (HCV) infection has been shown to be…
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Noninvasive biomarkers FibroTest and ActiTest versus liver biopsy in chronic hepatitis C patients: the Middle East experience.
…and inflammation grade in chronic hepatitis C (CHC) patients with liver biopsy…
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Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
…of liver fibrosis in chronic hepatitis C (CHC). Also, we examined whether…
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The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…APRI showed its best performance in HCV monoinfected cases, with an AdjAUROC…
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Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference. Key publication
…NAFLD) than in patients with chronic viral hepatitis. ### Aims To improve the…
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Validation of liver fibrosis biomarker (FibroTest) for assessing liver fibrosis progression: proof of concept and first application in a large population.
…770 with chronic hepatitis C, 723 with hepatitis B, 761 with non…
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication Meta Analysis
…validated in patients with chronic hepatitis C (CHC) and subsequently assessed in…
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Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.
…We prospectively assessed the performance of FibroScan in patients with chronic hepatitis…
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Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.
Transient elastography (TE) is a noninvasive technique to evaluate liver fibrosis. We…
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FibroTest and Fibroscan performances revisited in patients with chronic hepatitis C. Impact of the spectrum effect and the applicability rate.
…validated in patients with chronic hepatitis C (CHC) using the standard area…
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Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).
…related mortality in patients with chronic hepatitis C. The aim was to…
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Improved inflammatory activity with peginterferon alfa-2b maintenance therapy in non-cirrhotic prior non-responders: a randomized study.
### Background & Aims Therapeutic options for patients failing hepatitis C retreatment are limited…
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
…assess liver fibrosis in chronic hepatitis C (CHC) and is required to…
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Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
…have been extensively validated in chronic hepatitis C. This review updates the…
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FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC³ program.
…506 patients (35%) had undetectable HCV-RNA at TW12 (TW12neg), with 58…
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Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy. Key publication
…chronic hepatitis C (n=27), chronic hepatitis B (n=8), alcoholic liver…
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Liver biopsy analysis has a low level of performance for diagnosis of intermediate stages of fibrosis.
…from 20 consecutive patients with chronic liver disease or normal liver tissue…
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Validation of Ten Noninvasive Diagnostic Models for Prediction of Liver Fibrosis in Patients with Chronic Hepatitis B.
…fibrosis assessment in patients with chronic hepatitis B. However, the sensitivity, specificity…
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Non-invasive diagnosis of hepatitis B virus-related cirrhosis. Review
Chronic hepatitis B (CHB) infection is a major public health problem associated…
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Optimized stepwise combination algorithms of non-invasive liver fibrosis scores including Hepascore in hepatitis C virus patients.
…biopsy in hepatitis C virus (HCV)-infected patients. ### Aim To validate HS…
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Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.
### Background & Aims Chronic hepatitis C is both a virologic and fibrotic disease…
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Comparison of non-invasive fibrosis markers and classical liver biopsy in chronic hepatitis C.
…HCV-RNA-positive, HCV genotype 1, treatment-naive patients with chronic HCV…
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Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases.
…in 228 consecutive patients with chronic viral hepatitis, with (115) or without…
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Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.
…rarely been assessed in Asian chronic hepatitis B (CHB) patients. We aimed…
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LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis. Key publication
…cirrhosis). ### Conclusions In patients with chronic liver disease the LCR1 and LCR2…
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Relative performances of FibroTest, Fibroscan, and biopsy for the assessment of the stage of liver fibrosis in patients with chronic hepatitis C: a step toward the truth in the absence of a gold standard.
…standard in patients with chronic hepatitis C (CHC) and controls. ### Methods A…
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Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.
…events (LREs) in patients with chronic hepatitis B (CHB). ### Methods Consecutive patients…
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Prise en charge des personnes infectées par les virus de l’hépatite B ou de l’hépatite C — Rapport de recommandations 2014 Key publication
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Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.
### Background And Aims Despite the high prevalence of chronic hepatitis B (CHB…
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Diagnostic accuracy of the Coopscore© to predict liver fibrosis in human immunodeficiency virus/hepatitis B virus co-infection.
Background Non-invasive methods for assessing liver fibrosis are increasingly used as…
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness. Review
The assessment of the fibrotic evolution of chronic hepatitis has always been…
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Variability in definitions of transaminase upper limit of the normal impacts the APRI performance as a biomarker of fibrosis in patients with chronic hepatitis C: "APRI c'est fini ?".
…When this AST-ULN variability was applied to the chronic hepatitis group…
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Performances of Elasto-FibroTest(®), a combination between FibroTest(®) and liver stiffness measurements for assessing the stage of liver fibrosis in patients with chronic hepatitis C.
…fibrosis in patients with chronic hepatitis C (CHC). The combination between FibroTest…
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Liver fibrosis markers in alcoholic liver disease. Review
Alcohol is one of the main factors of liver damage. The evaluation…
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Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).
…F4.3) in patients with chronic hepatitis B (CHB). The second aim…
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Biomarkers as a first-line estimate of injury in chronic liver diseases: time for a moratorium on liver biopsy?
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis. Review
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
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Peta V, Ziol M, Imbert-Bismut F, et al., for the FibroFrance-GHPS-HECAM group
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Meta-analyses of FibroTest diagnostic value in chronic liver disease. Key publication Meta Analysis
…validated in patients with chronic hepatitis C (CHC). The aim was to…
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Editorial: FibroTest to predict liver-related mortality in NAFLD. Should this change the diagnostic algorithm in NAFLD?
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Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver.
### Background The only way to diagnose nodular regenerative hyperplasia (NRH) is liver…
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Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
…LSM and FT in Asian chronic hepatitis B (CHB) patients. ### Methods Between…
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FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis. Meta Analysis
…need for active treatment in chronic hepatitis B (CHB). Noninvasive alternatives such…
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Input of serum haptoglobin fucosylation profile in the diagnosis of hepatocellular carcinoma in patients with non-cirrhotic liver disease. Key publication
…of HCC in patients with chronic liver disease including those without cirrhosis…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV. Review
…with other conditions such as HCV, HBV, and NAFLD. Identifying HIV-infected…
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Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.
…As HCV clearance may improve liver outcomes, we assessed hepatic fibrosis and…
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Diagnostic value of serum protein profiling by SELDI-TOF ProteinChip compared with a biochemical marker, FibroTest, for the diagnosis of advanced fibrosis in patients with chronic hepatitis C.
…liver fibrosis in patients with chronic hepatitis C. ### Aim To compare FibroTest…
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Assessment of liver fibrosis: noninvasive means.
…most frequent chronic liver diseases chronic hepatitis C (HCV), B (HBV) non…
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
…value as prognostic tests in chronic liver disease, and in particular in…
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Biomarkers of liver fibrosis. Review
…four more common chronic liver diseases: C virus (HCV), hepatitis B virus…
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