Publications scientifiques sur les diagnostics non invasifs BioPredictive
Études évaluées par les pairs validant les diagnostics sanguins BioPredictive pour les maladies du foie — des cohortes pionnières aux méta-analyses à long terme.
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Résultats pour
“Aspartate aminotransferase to platelet ratio index”
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Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.
…the platelet count, age-platelet index, aspartate aminotransferase-platelet ratio index (APRI…
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Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.
…FibroTest®, aspartate aminotransferase-to-platelet ratio index(APRI), aspartate aminotransferase and alanine…
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Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.
…FS, Fibrotest, FIB-4, aspartate aminotransferase to platelet ratio index (APRI), and…
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FibroTest has better diagnostic and prognostic values than the aspartate aminotransferase-to-platelet ratio index in patients with chronic hepatitis C.
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Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
…France) M probe; aspartate aminotransferase to platelet ratio index (APRI) and FibroTest…
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Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C. Review
…73.8, 94.9%, aspartate aminotransferase to platelet ratio index (APRI): 71…
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Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection. Review
…Due to the complex natural history of HBV infection, patients require an…
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Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
…The aim of the present study was to evaluate dynamic changes of…
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The effectiveness of noninvasive biomarkers to predict hepatitis B-related significant fibrosis and cirrhosis: a systematic review and meta-analysis of diagnostic test accuracy. Meta Analysis
Noninvasive biomarkers have been developed to predict hepatitis B virus (HBV)-related…
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Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
…The aim of the study was to evaluate the selected parameters of…
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Comparison of transient elastography (FibroScan), FibroTest, APRI and two algorithms combining these non-invasive tests for liver fibrosis staging in HIV/HCV coinfected patients: ANRS CO13 HEPAVIH and FIBROSTIC collaboration.
…Fibrotest (FT), the aspartate aminotransferase-to-platelet ratio index (APRI) and two…
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The non-invasive assessment of hepatic fibrosis. Review
…The liver biopsy with the histopathological examination is considered to be the…
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Prospective noninvasive analysis of hepatic fibrosis in patients with Crohn's disease: correlation of transient elastography and laboratory-based markers.
…Established markers of fibrosis, namely, aspartate transaminase-to-platelet ratio index (APRI…
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Comparison of non-invasive fibrosis markers and classical liver biopsy in chronic hepatitis C.
…platelet ratio index (APRI), age-platelet (AP) index, Göteborg University cirrhosis index…
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The predictive value of Fibrotest vs. APRI for the diagnosis of fibrosis in chronic hepatitis C.
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Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. Review
…to first tier screening of patients at risk, in order to diagnose…
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Combination of fibrosis tests: sequential or synchronous?
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Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.
…markers (Hepascore, Aspartate Transaminase (AST) to platelet ratio index [APRI], Forns score…
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Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
…and 0.71 (aspartate aminotransferase-to-platelet ratio index), 0.80 and…
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Progression of liver fibrosis among injection drug users with chronic hepatitis C.
…Predictive values of blood markers [FibroSURE, aspartate aminotransferase-to-platelet-ratio index…
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Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
…fibrosis (FibroTest, the aspartate aminotransferase to platelet ratio index, FIB-4), and…
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Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B.
…AST-to-Platelet ratio (APRI), Fornso index, AST-to-ALT Ratio, Goteborg…
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Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.
…liver biopsy and aspartate aminotransferase-to-platelet ratio (APRI), fibrosis index-4…
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Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
…hyaluronic acid (HA), aspartate aminotransferase platelet ratio index (APRI), FibroTest, and Fib…
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Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
…Cut-offs were determined by Youden Index or 90% predictive values. ### Results…
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Variability in definitions of transaminase upper limit of the normal impacts the APRI performance as a biomarker of fibrosis in patients with chronic hepatitis C: "APRI c'est fini ?".
### Background The aspartate aminotransferase platelet ratio index (APRI) is a validated, non…
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Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.
Aim To assess concordance of eight frequently used serology-based scoring indices…
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Evaluating the accuracy and increasing the reliable diagnosis rate of blood tests for liver fibrosis in chronic hepatitis C.
…0.799, aspartate aminotransferase to platelet ratio index (APRI): 0.786 and…
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Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.
…of Fibrotest, Forns' index and AST-to-platelet ratio (APRI) have been…
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Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
…SteatoTest, Forns index, aspartate aminotransferase to platelet ratio index, ultrasound, and Fibroscan…
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Non-invasive assessment of liver fibrosis: are we ready?
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Prognostic value of liver fibrosis biomarkers: a meta-analysis.
…such as FibroTest, aspartate transaminase-platelet ratio index (APRI), FIB-4, and…
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Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers. Review
…4 index are both cost-effective and highly sensitive tools to exclude…
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Performance of noninvasive markers for liver fibrosis is reduced in chronic hepatitis C with normal transaminases.
…AST-to-platelet ratio, Forns' index, AST-to-ALT ratio (AAR), Fibrotest…
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Liver stiffness measurement in children using FibroScan: feasibility study and comparison with Fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy.
…to compare FibroScan, Fibrotest, and aspartate transaminase to platelets ratio index (APRI…
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Transient elastography and biomarkers for liver fibrosis assessment and follow-up of inactive hepatitis B carriers.
…TE, Fibrotest and aspartate to platelet ratio index (APRI) the same day…
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis. Review
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
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Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores.
…AST/ALT ratio (AAR), APRI, prothrombin index (PI), platelet count (PC), FibroTest…
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The predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and Forns index to noninvasively estimate fibrosis in hepatitis C and nonhepatitis C liver diseases.
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Biomarkers of liver fibrosis. Review
…FT has higher accuracy than aspartate aminotransferase/platelets ratio index (APRI), the…
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Discordance between liver biopsy and FibroTest in assessing liver fibrosis in chronic hepatitis B.
…Here, we aimed to identify predictors of discordance between FT and liver…
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Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.
…Fibrotest, the Forn's index, age-platelet ratio index, SHASTA, FIB-4…
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Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection.
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The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…APRI, Forns'index, Lok index, AST-to-ALT ratio, Fib-4, platelets…
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Study on noninvasive laboratory tests for fibrosis in chronic HBV infection and their evaluation.
…were able to exclude fibrosis with a negative likelihood ratio <0.1…
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Validation and comparison of indexes for fibrosis and cirrhosis prediction in chronic hepatitis C patients: proposal for a pragmatic approach classification without liver biopsies.
…FibroTest (FT), aspartate aminotransferase to platelet ratio index (APRI) and Forns score…
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Non-invasive markers for hepatic fibrosis. Review
…Current non-invasive methods range from serum biomarker assays to advanced imaging…
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Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease. Key publication
…The primary aim was to validate ELF in detection of advanced fibrosis…
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Usefulness of acoustic radiation force impulse and fibrotest in liver fibrosis assessment after liver transplant.
…This study aimed to assess the accuracy of ARFI in discriminating liver…
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Noninvasive Assessment of Liver Fibrosis. Key publication Review
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Diffusion-weighted magnetic resonance imaging for the assessment of fibrosis in chronic hepatitis C.
…06) for the aspartate aminotransferase to platelets ratio index (APRI), 0.86…
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The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B.
…index was more precise than the AST-to-platelet ratio index and…
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Biomarkers for liver disease in urea cycle disorders.
### Background Urea cycle disorders (UCDs) are among the most common inborn errors…
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Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.
…When subjects were divided into three groups according to quartile stratification (low…
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Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
…to platelet ratio index. Histologic steatosis significantly correlated with body mass index…
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Comparison of liver fibrosis blood tests developed for HCV with new specific tests in HIV/HCV co-infection.
### Background & Aims We compared 5 non-specific and 2 specific blood tests…
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Non-invasive diagnosis of hepatitis B virus-related cirrhosis. Review
…Twenty-three percent of patients with CHB progress naturally to liver cirrhosis…
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Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
…aim of this study was to determine the accuracy of certain biomarkers…
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Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
### Introduction Identifying liver fibrosis is important to evaluate the severity of liver…
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Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
### Objective To determine practices among physicians in Canada for the assessment of…
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Biological markers of liver fibrosis and activity as non-invasive alternatives to liver biopsy in patients with chronic hepatitis C and associated mixed cryoglobulinemia vasculitis.
…age-platelet, platelet, hyaluronic acid) as non-invasive alternatives to liver biopsy…
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Optimized stepwise combination algorithms of non-invasive liver fibrosis scores including Hepascore in hepatitis C virus patients.
…AUCs of aspartate aminotransferase (AST) to Platelets Ratio Index (APRI) and Forns…
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Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
…METAVIR F stages, body mass index, and platelet count were also independently…
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Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis. Review
…Transient elastography also appears to be an excellent tool for early detection…
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Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication Review
…A scoring system has been updated to better compare the quality of…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
…In multivariate analysis, FibroTest and liver stiffness had the highest hazard ratio…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV. Review
Patients with HIV have a proclivity to develop liver fibrosis, especially when…
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Comparison of test performance profile for blood tests of liver fibrosis in chronic hepatitis C.
…This has to be considered during the interpretation process. Moreover, the performance…
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A Single Test Combining Blood Markers and Elastography is More Accurate Than Other Fibrosis Tests in the Main Causes of Chronic Liver Diseases.
…0.750, aspartate aminotransferase platelet ratio index: 0.742, Fib-4: 0…
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A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation. Review
…Different invasive and non invasive methods are applied to diagnose the disease…
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Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.
…FT) (Castera) or AST-to-Platelet Ratio Index (APRI) and FT (SAFE…
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Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.
As an alternative to liver biopsy, an index of five biochemical markers…
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Assessment of liver fibrosis: noninvasive means.
Liver biopsy, owing to its limitations and risks, is an imperfect gold…
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Validation of Ten Noninvasive Diagnostic Models for Prediction of Liver Fibrosis in Patients with Chronic Hepatitis B.
…The aim of this study was to verify the diagnostic performance and…
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Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.
…Biopredictive; and the aspartate transaminase to platelets ratio index [APRI]); a liver…
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Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: the fibrovic study--ANRS HC02.
…Fib-4, APRI and the Forn's index were only able to…
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Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy.
…The study population was subdivided according to baseline FibroSURE test results into…
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Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.
…We aimed to validate its diagnostic performances in comparison with liver stiffness…
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Diagnostic algorithms for liver fibrosis in hepatitis C: are they ready to avoid liver biopsy?
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FIB-4: a simple, inexpensive and accurate marker of fibrosis in HCV-infected patients.
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Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasive.
…FibroTest with the aspartate aminotransferase-to-platelet ratio index (APRI) or FibroScan…
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Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
As of 2016, there is no evidence-based pathway to stratify the…
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An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
…Lower index scores at baseline that continue to decline likely reflect reduced…
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Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.
…leading to special need of non-invasive validated methods to estimate liver…
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External validation of FibroIndex.
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Hepatitis B: are non-invasive markers of liver fibrosis reliable? Review
Liver biopsy, which was traditionally considered to be the gold standard for…
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
…Non-invasive tests (NITs) are increasingly used to detect fibrosis, but their…
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Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
…However, to date, diagnostic performances of Enhanced Liver Fibrosis (ELF) test, which…
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FibroSURE as a noninvasive marker of liver fibrosis and inflammation in chronic hepatitis B.
…When we combined the fibrosis score determined by FibroSURE with aspartate aminotransferase…
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SAFE biopsy: a validated method for large-scale staging of liver fibrosis in chronic hepatitis C.
…to-platelet ratio index and Fibrotest-Fibrosure, thereby limiting liver biopsy to…
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Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers.
…Therefore, early detection of fibrosis is essential to identify patients at risk…
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness. Review
…suggested that the AST-to-platelet ratio index or FIB-4 test…
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Development and validation of a nomogram based on clinical factors and standard laboratory tests for prediction of clinically significant liver fibrosis in chronic hepatitis C virus infection.
…Age at biopsy, aspartate aminotransferase, γ-glutamyl transpeptidase, albumin, platelet count, and…
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Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.
…4 index (FIB-4), aspartate-aminotransferase-to-platelet-ratio index] and AFP…
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Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.
### Purpose To compare the diagnostic performance of acoustic radiation force impulse (ARFI…
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Predicting significant fibrosis in hepatitis C patients in Luxembourg using serological markers.
### Objective The aim of our study was to assess the diagnostic performance…
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Changes of non-invasive markers and FibroScan values during HCV treatment.
…The aim of this prospective study was to evaluate changes in liver…
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Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
…performance to detect advanced fibrosis and cirrhosis. However, aspartate aminotransferase levels must…
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Non-invasive biomarkers of liver fibrosis in haemophilia patients with hepatitis C: can you avoid liver biopsy?
…FT, AST-to-platelet ratio index (APRI), Forns index, age-platelet index…
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Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference. Key publication
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Successful treatment with telaprevir-based regimens for chronic hepatitis C results in significant improvements to serum markers of liver fibrosis.
…We sought to quantify whether liver health improves following successful treatment with…
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Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
…The aim of the study was to compare the diagnostic and prognostic…
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Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests.
…Aims To assess Fibroscan for non-invasive diagnosis of asymptomatic liver fibrosis…
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Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
…nonalcoholic fatty liver disease leading to cirrhosis. Existing guidelines do not advocate…
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Validation of biochemical markers for the prediction of liver fibrosis and necroinflammatory activity in hemodialysis patients with chronic hepatitis C.
…biopsy and the AST-to-platelet ratio index (APRI) in determining hepatic…
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Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication
Liver fibrosis is a common pathway leading to cirrhosis, which is the…
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Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C.
…evaluated for AST to platelets ratio (APRI), Forns' index and Fibrotest at…
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Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts. Key publication
…The primary objective of the present study was to investigate whether the…
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Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.
…The aim of this study was to prospectively evaluate the performance of…
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Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection
…These recommendations provide opportunities to save lives, improve clinical outcomes of persons…
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A novel panel of blood markers to assess the degree of liver fibrosis.
…test combining platelets, prothrombin index, aspartate aminotransferase, alpha2-macroglobulin (A2M), hyaluronate, urea…
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Noninvasive evaluation of NAFLD. Review
A common clinical concern in patients with NAFLD is whether they have…
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EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
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Improving estimation of liver fibrosis using combination and newer noninvasive biomarker scoring systems in hepatitis C-infected haemophilia patients.
…FT, AST-to-platelet ratio index (APRI), Forns index, hyaluronic acid and…
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Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Key publication
…We aimed, in our prospective study, to assess the predictive value of…
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B. Meta Analysis
…accuracy of FibroTest, aspartate aminotransferase-platelet ratio index (APRI), FIB4 or TE…
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Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
…to 0.78)], with very low specificity. Regarding NASH, alanine aminotransferase ≥36…
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Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
…mortality and cardiovascular risk. ### Aim To evaluate the prognostic value of non…
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Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.
…In this study, we aimed to design a new score in chronic…
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Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by FibroScan in non-alcoholic fatty liver disease.
…score, FibroMeter(NAFLD), aspartate aminotransferase to platelet ratio index (APRI), FIB4, FibroTest…
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Altered serum N-glycomics in chronic hepatitis B patients.
…Our present study aimed to evaluate the use of serum glycan markers…
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Transient elastography alone and in combination with FibroTest® for the diagnosis of hepatic fibrosis in alcoholic liver disease.
### Background & Aims The reliability of transient elastography (TE) to assess liver fibrosis…
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Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study. Key publication
…This study aimed to investigate whether the biomarkers of MASLD included in…
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An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
…In addition, recommendations are made regarding approaches to reducing the burden of…
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Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
…The aim of this study was to determine the diagnostic utility of…
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Commentary: prognostication of chronic hepatitis B--are Fibrotest and Fibroscan the final answers?
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Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.
…Hepascore®) to 0.83 (FIB-4) for cirrhosis. ### Conclusions Contrarily to blood…
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Guidelines for the Screening, Care and Treatment of Persons with Hepatitis C Infection Key publication
…the expansion of clinical services to patients with HCV infection, as they…
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Fibrotest or Fibroscan for evaluation of liver fibrosis in haemophilia patients infected with hepatitis C.
Non-invasive modalities to estimate fibrosis stage are desirable in hepatitis C…
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
In Egypt, as elsewhere, liver biopsy (LB) remains the gold standard to…
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Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
### Objectives To evaluate the diagnostic performance of seven non-invasive tests (NITs…
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Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
…The aim of this case-control study was to determine factors associated…
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The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
### Aim To assess the diagnostic value of FibroTest to discriminate between insignificant…
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The risk of multiplying diagnostic combinations in the absence of a perfect gold standard for a fibrosis test.
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Noninvasive diagnosis in alcohol-related liver disease.
…Among the noninvasive surrogate markers and techniques used to detect liver fibrosis…
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Reproducibility of blood tests of liver fibrosis in clinical practice.
### Objectives To evaluate the inter-laboratory reproducibility of blood test for liver…
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Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies. Meta Analysis
…We aimed to review evidence-based published data of biomarkers that have…
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Performance of 11 biomarkers for liver fibrosis assessment in HIV/HBV co-infected patients.
…The Kappa index was used to study overall agreement with liver biopsy…
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External Validation of LCR1-LCR2, a Multivariable Hepatocellular Carcinoma Risk Calculator, in a Multiethnic Cohort of Patients With Chronic Hepatitis B. Key publication
…The aim was to externally validate LCR1-LCR2 in hepatitis B. ### Methods…
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Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
…liver fibrosis and cirrhosis. ### Aim To determine the diagnostic accuracy of ARFI…
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American Association for the Study of the Liver
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The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
…Of those with baseline F3 disease, 16.7% experienced disease progression to…
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FibroMAX: towards a new universal biomarker of liver disease? Review
…and a better benefit-to-risk ratio than biopsy of five combinations…
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Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.
…and was superior to other noninvasive methods (APRI Index, FibroMax) for staging…
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Guidelines for the diagnosis of uncomplicated cirrhosis.
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Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
…The impact of other risk factors, including prolonged exposure to combined antiretroviral…
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Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C. Key publication
…The aims of this study were to assess the quality of biopsy…
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Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
…Although the increasing prevalence of NAFLD is frequently attributed to the epidemic…
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Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus.
…The purpose of this study was to assess the performance of these…
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Noninvasive Assessment of Liver Fibrosis.
…TE appears to be an excellent tool for the early detection of…
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FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
### Aim To compare histological endpoint assessment using noninvasive alternatives to biopsy during…
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Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods. Review
…The articles cited were selected based on their relevancy to the objective…
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Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.
The diagnostic utilities of ultrasonography (US), fatty liver index (FLI) and an…
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Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
…Hepatic stellate cell activation index was also higher in CHC than in…
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Clinical and genetic definition of serum bilirubin levels for the diagnosis of Gilbert syndrome and hypobilirubinemia.
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Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.
### Background/Aims According to guidelines, the histological diagnosis of severe alcoholic steatohepatitis…
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Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis. Review
…The analysis also aimed to compare the diagnostic accuracy of transient elastography…
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[Biomarkers for liver fibrosis: advances, advantages and disadvantages]. Review
Liver cirrhosis in Mexico is one of the most important causes of…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.
…lead to an increased awareness of liver disease severity. ### Objective To compare…
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Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
…The aim of the present study was to evaluate the prevalence of…
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Liver fibrosis regression and progression during controlled hepatitis B virus infection among HIV-HBV patients treated with tenofovir disoproxil fumarate in France: a prospective cohort study.
…The aim of this study was to evaluate the evolution of liver…
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The Diagnostic Value of FibroTest and Hepascore as Non-Invasive Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC).
The aim of this study was to evaluate the diagnostic usefulness of…
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FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC³ program.
…The aim of the present study was to assess FibroTest (FT), a…
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication Meta Analysis
…The primary aim of the present study was to update a previous…
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Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
…status, viral load, and alanine aminotransferase value. Only two biomarkers had several…
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Management of the patient with SVR. Review
…Additional benefits include reduced morbidity related to extrahepatic and systemic manifestations of…
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The new paradigm of hepatitis C therapy: integration of oral therapies into best practices. Review
…In replacing interferon-based therapies, all-oral regimens are expected to be…
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Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…Database (from 1995 to January 2010), Cumulative Index to Nursing and Allied…
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
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Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes. Key publication
…steatohepatitis (NASH) and steatosis. ### Aims To validate externally the performances of a…
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EASL Clinical Practice Guidelines: management of hepatitis C virus infection.
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Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication
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