Publications scientifiques sur les diagnostics non invasifs BioPredictive

Études évaluées par les pairs validant les diagnostics sanguins BioPredictive pour les maladies du foie — des cohortes pionnières aux méta-analyses à long terme.

141/435 Résultats pour
“non-alcoholic steatohepatitis”

“non-alcoholic steatohepatitis” Tout effacer
  1. The Distribution of Liver Steatosis, Fibrosis, Steatohepatitis and Inflammation Activity in Alcoholics According to FibroMax Test.

    Gudowska M et al. · Adv Clin Exp Med · 2015 Score 100

    …94.1%--alcoholic steatohepatitis, 56.6%--non-alcoholic steatohepatitis and 33.6…

    ActiTest AshTest FibroTest NashTest +2

  2. The Higher Prevalence of Non-Alcoholic versus Alcoholic Steatohepatitis in Alcoholics.

    Gruszewska E et al. · Clin Lab · 2015 Score 100

    …Co-occurrence of alcoholic steatohepatitis and non-alcoholic steatohepatitis in alcoholic patients…

    AshTest NashTest Alcohol

  3. Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers. Review

    Vilar-Gomez E et al. · J Hepatol · 2018 Score 100

    The correct identification of patients at increased risk of non-alcoholic steatohepatitis

    FibroTest Metabolic

  4. Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods. Review

    Festi D et al. · Aliment Pharmacol Ther · 2013 Score 99

    …0.83; 0.91) for the diagnosis of non-alcoholic steatohepatitis (NASH…

    SteatoTest

  5. Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review

    Bril F et al. · Diabetes Care · 2017 Score 99

    …Diabetes appears to promote the development of nonalcoholic steatohepatitis (NASH), the more…

    FibroTest Metabolic

  6. EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease.

    European Association for the Study of the Liver (EASL) et al. · Obes Facts · 2016 Score 99

    FibroTest SteatoTest Metabolic

  7. Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.

    Lassailly G et al. · Eur J Gastroenterol Hepatol · 2011 Score 98

    …fibrosis (FibroTest), steatosis (SteatoTest), and steatohepatitis (NashTest, ActiTest) in these patients. ### Materials…

    FibroTest NashTest SteatoTest Metabolic

  8. FibroMAX: towards a new universal biomarker of liver disease? Review

    Morra R et al. · Expert Rev Mol Diagn · 2007 Score 98

    …nonalcoholic steatohepatitis; and AshTest for the quantitative assessment of alcoholic steatohepatitis (also…

    ActiTest AshTest FibroTest NashTest +7

  9. Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication Review

    Munteanu M et al. · J Gastrointestin Liver Dis · 2008 Score 98

    ActiTest AshTest FibroTest NashTest +6

  10. A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.

    Ratziu V et al. · J Hepatol · 2011 Score 97

    ### Background & Aims Nonalcoholic steatohepatitis (NASH) is a prevalent liver disease associated with…

    FibroTest Metabolic

  11. The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.

    Netanel C et al. · Am J Surg · 2021 Score 97

    …and steatohepatitis are significantly improved by SG as measured by non-invasive…

    FibroTest NashTest SteatoTest Metabolic

  12. Screening for liver disease using non-invasive biomarkers (FibroTest, SteatoTest and NashTest) in patients with hyperlipidaemia.

    Ratziu V et al. · Aliment Pharmacol Ther · 2007 Score 97

    …with steatohepatitis (non-alcoholic steatohepatitis, NASH). ### Aims To use the non-invasive…

    FibroTest NashTest SteatoTest Metabolic

  13. Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus.

    Bril F et al. · J Investig Med · 2019 Score 96

    …establish the diagnosis of non-alcoholic steatohepatitis (NASH) and to grade and…

    ActiTest FibroTest NashTest SteatoTest +1

  14. Hepatoprotective Effect of Antrodia cinnamomea Mycelium in Patients with Nonalcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial.

    Chiou YL et al. · J Am Coll Nutr · 2021 Score 96

    ### Objective Nonalcoholic steatohepatitis (NASH) has become a prominent liver disease in contemporary…

    ActiTest FibroTest SteatoTest Metabolic

  15. The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.

    Younossi ZM et al. · Gastroenterology · 2021 Score 96

    ### Background & Aim Fibrosis is an independent predictor of death in nonalcoholic steatohepatitis

    FibroTest Metabolic

  16. Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference. Key publication

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2018 Score 95

    …for the diagnosis of nonalcoholic steatohepatitis (NASH) using a simplified histological definition…

    FibroTest NashTest SteatoTest Metabolic

  17. Performance of Plasma Biomarkers and Diagnostic Panels for Nonalcoholic Steatohepatitis and Advanced Fibrosis in Patients With Type 2 Diabetes.

    Bril F et al. · Diabetes Care · 2020 Score 95

    …for the diagnosis of nonalcoholic steatohepatitis (NASH) and advanced fibrosis has not…

    FibroTest NashTest-2 Metabolic

  18. Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials.

    Jullian-Desayes I et al. · Respirology · 2016 Score 94

    …displayed borderline or possible non-alcoholic steatohepatitis (NASH). Six to twelve weeks…

    NashTest SteatoTest Metabolic

  19. Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients.

    Bedossa P et al. · Hepatology · 2012 Score 94

    …An algorithm for segregating lesions into normal liver, NAFLD, or nonalcoholic steatohepatitis

    Metabolic

  20. Noninvasive Testing for Nonalcoholic Steatohepatitis and Hepatic Fibrosis in Patients With Psoriasis Receiving Long-term Methotrexate Sodium Therapy.

    Bauer B et al. · JAMA Dermatol · 2017 Score 94

    …a noninvasive test for nonalcoholic steatohepatitis (NASH) and hepatic fibrosis, can be…

    FibroTest NashTest Other

  21. Noninvasive evaluation of NAFLD. Review

    Castera L et al. · Nat Rev Gastroenterol Hepatol · 2013 Score 93

    A common clinical concern in patients with NAFLD is whether they have…

    ActiTest FibroTest NashTest SteatoTest +1

  22. [The diagnostic value of non-invasive biochemical biomarkers in alcohol abuse].

    Supronowicz Ł et al. · Pol Merkur Lekarski · 2013 Score 93

    …and alcoholic steatohepatitis, can be evaluated by means of non-invasive biochemical…

    AshTest FibroTest SteatoTest Alcohol

  23. Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.

    Grattagliano I et al. · Ann Hepatol · 2013 Score 93

    …of patients at risk for steatohepatitis. With a sensitivity of 50% and…

    ActiTest FibroTest NashTest SteatoTest +1

  24. Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population.

    Zelber-Sagi S et al. · Transl Res · 2015 Score 92

    Retrospective studies suggest that coffee consumption may exert beneficial effects in patients…

    FibroTest SteatoTest Metabolic

  25. Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.

    Pais R et al. · Eur J Intern Med · 2015 Score 92

    ### Unlabelled The association of NAFLD with chronic hepatitis C (CHC) has been…

    FibroTest SteatoTest HBV HCV +1

  26. Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.

    Minville C et al. · Chest · 2014 Score 92

    …used to evaluate steatosis, nonalcoholic steatohepatitis (NASH), and fibrosis in a large…

    FibroTest NashTest SteatoTest Metabolic

  27. Non-invasive evaluation of response to obeticholic acid in patients with NASH: Results from the REGENERATE study.

    Rinella ME et al. · J Hepatol · 2022 Score 91

    ### Background & Aims Non-alcoholic steatohepatitis (NASH) is a chronic, progressive fibrotic liver…

    FibroTest Metabolic

  28. Fibromax-based nonalcoholic fatty liver disease in chronic obstructive pulmonary disease patients with obstructive sleep apnea: Methodological considerations.

    Monneret D · F1000Res · 2017 Score 91

    …liver fibrosis, steatosis and nonalcoholic steatohepatitis (NASH) in COPD patients, some of…

    FibroTest NashTest SteatoTest Metabolic

  29. The product of triglycerides and glucose as biomarker for screening simple steatosis and NASH in asymptomatic women.

    Simental-Mendía LE et al. · Ann Hepatol · 2016 Score 91

    …screening simple steatosis and non-alcoholic steatohepatitis (NASH) in asymptomatic women, and…

    NashTest SteatoTest Metabolic

  30. Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.

    Rudler M et al. · PLoS One · 2015 Score 90

    ### Background/Aims According to guidelines, the histological diagnosis of severe alcoholic steatohepatitis

    AshTest Alcohol

  31. Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.

    Lemoine M et al. · J Acquir Immune Defic Syndr · 2019 Score 90

    …Noninvasive tests of steatosis, nonalcoholic steatohepatitis (NASH), and fibrosis have been poorly…

    FibroTest NashTest SteatoTest HIV

  32. Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy. Key publication

    Anastasiou J et al. · Eur J Gastroenterol Hepatol · 2010 Score 90

    …as autoimmune hepatitis, alcoholic liver disease and nonalcoholic steatohepatitis. In this study…

    ActiTest FibroTest Alcohol HBV +3

  33. Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review

    Moreno C et al. · J Hepatol · 2019 Score 89

    …During the last decade, non-invasive tests have been developed to estimate…

    FibroTest Alcohol

  34. Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis. Key publication

    Poynard T et al. · Aliment Pharmacol Ther · 2023 Score 89

    ### Background No prospective diagnostic studies have directly compared widespread non-invasive liver…

    FibroTest-T2D NashTest-T2D SteatoTest-T2D Metabolic

  35. Silymarin in non alcoholic fatty liver disease.

    Cacciapuoti F et al. · World J Hepatol · 2013 Score 88

    …effects of silybum marianum on non alcoholic fatty liver disease (NAFLD). ### Methods…

    SteatoTest Metabolic

  36. Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.

    Viglino D et al. · Sci Rep · 2018 Score 88

    …used to evaluate steatosis, non-alcoholic steatohepatitis (NASH) and liver fibrosis. Univariate…

    FibroTest NashTest SteatoTest Metabolic

  37. Editorial: FibroTest to predict liver-related mortality in NAFLD. Should this change the diagnostic algorithm in NAFLD?

    Bush AM et al. · Aliment Pharmacol Ther · 2018 Score 88

    FibroTest Metabolic

  38. Current complications and challenges in nonalcoholic steatohepatitis screening and diagnosis. Review

    Golabi P et al. · Expert Rev Gastroenterol Hepatol · 2016 Score 87

    Nonalcoholic steatohepatitis (NASH) can lead to complications such as liver failure, cirrhosis…

    FibroTest Metabolic

  39. Dietary vitamin E and C intake is inversely associated with the severity of nonalcoholic fatty liver disease.

    Ivancovsky-Wajcman D et al. · Dig Liver Dis · 2019 Score 87

    …fatty liver disease (NAFLD) and steatohepatitis (NASH), there is limited evidence regarding…

    FibroTest NashTest SteatoTest Metabolic

  40. Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.

    Friedrich-Rust M et al. · J Clin Gastroenterol · 2010 Score 87

    ### Background In recent years noninvasive methods have been evaluated for the assessment…

    FibroTest SteatoTest Other

  41. Screening for Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Advanced Fibrosis in Diabetology: A Prospective Multicenter Study.

    Caussy C et al. · Diabetes Care · 2025 Score 86

    ### Objective Screening for advanced fibrosis (AF) resulting from metabolic dysfunction-associated steatotic…

    FibroTest Metabolic

  42. Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease.

    Viglino D et al. · Eur Respir J · 2017 Score 86

    …SteatoTest, NashTest and FibroTest) were used to assess steatosis, nonalcoholic steatohepatitis (NASH…

    FibroTest NashTest SteatoTest Metabolic

  43. Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication

    Poynard T et al. · BMC Gastroenterol · 2006 Score 86

    …with non-alcoholic fatty liver disease, NashTest, a simple and non-invasive…

    NashTest Metabolic

  44. Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes. Key publication

    Poynard T et al. · Aliment Pharmacol Ther · 2021 Score 85

    …main histological features, fibrosis, non-alcoholic steatohepatitis (NASH) and steatosis. ### Aims To…

    FibroTest NashTest-2 SteatoTest Metabolic

  45. EASL clinical practical guidelines: management of alcoholic liver disease.

    European Association for the Study of Liver · J Hepatol · 2012 Score 85

    FibroTest Alcohol

  46. Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. Review

    Lombardi R et al. · World J Gastroenterol · 2015 Score 85

    …ranging from simple steatosis to alcoholic steatohepatitis and cirrhosis. Fatty liver develops…

    FibroTest Alcohol

  47. The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.

    Lynch M et al. · JAMA Dermatol · 2014 Score 84

    …pattern of fibrosis attributed to steatohepatitis. ### Conclusions And Relevance Transient elastography and…

    FibroTest Other

  48. Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication

    Ratziu V et al. · BMC Gastroenterol · 2006 Score 84

    …the gold standard for assessing non-alcoholic fatty liver disease (NAFLD) histologic…

    FibroTest Metabolic

  49. The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication

    Poynard T et al. · Comp Hepatol · 2005 Score 83

    …C and B, alcoholic liver disease, and non-alcoholic fatty liver disease…

    SteatoTest Alcohol HBV HCV +1

  50. Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19. Key publication

    Deckmyn O et al. · Biomedicines · 2022 Score 83

    In patients with non-alcoholic fatty liver disease (NAFLD) with or without…

    FibroTest Metabolic

  51. Noninvasive Markers of Improvement of Liver Steatosis Achieved by Weight Reduction in Patients with Nonalcoholic Fatty Liver Disease.

    Copaci I et al. · Rom J Intern Med · 2015 Score 83

    ### Unlabelled Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance…

    SteatoTest Metabolic

  52. Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.

    Cassinotto C et al. · Radiology · 2013 Score 82

    …viral hepatitis (n = 136), alcoholic or nonalcoholic steatohepatitis disorders (n = 113), or…

    FibroTest Alcohol HBV HCV +2

  53. Biomarkers of liver fibrosis. Review

    Poynard T et al. · Adv Clin Chem · 2008 Score 82

    …disease, hepatitis C, hepatitis B, alcoholic or nonalcoholic fatty liver disease. High…

    ActiTest FibroTest SteatoTest Alcohol +5

  54. Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication Review

    Poynard T et al. · Gastroenterol Clin Biol · 2008 Score 82

    This review summarizes the methodological aspects of the interpretation of non-invasive…

    ActiTest FibroTest SteatoTest Alcohol +5

  55. Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.

    Meritsi A et al. · Clin Diabetes · 2022 Score 81

    Nonalcoholic fatty liver disease (NAFLD) is dramatically increasing in parallel with the…

    ActiTest FibroTest NashTest-2 Metabolic

  56. Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.

    Fernandez M et al. · Eur J Gastroenterol Hepatol · 2015 Score 81

    …off values for use in alcoholic liver disease (ALD). The aims of…

    FibroTest Alcohol

  57. Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study.

    Fouad A et al. · Int J Gen Med · 2013 Score 81

    ### Background Steatosis is common in patients with hepatitis C virus (HCV) infection…

    HCV

  58. Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). Key publication

    Poynard T et al. · Diagnostics (Basel) · 2025 Score 80

    **Background/Objectives:** Bariatric surgery (BS), drugs approved for type-2-diabetes (T2D…

    FibroTest-T2D Metabolic

  59. Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases.

    Poinsot P et al. · J Clin Lipidol · 2017 Score 80

    ### Background The childhood/adult-onset lysosomal acid lipase deficiency (LALD; late-onset…

    FibroTest Metabolic

  60. Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics.

    Chrostek L et al. · Biomed Res Int · 2019 Score 80

    …The best marker of liver fibrosis in alcoholic patients seems to be…

    FibroTest Alcohol

  61. Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts. Key publication

    Denimal D et al. · Cardiovasc Diabetol · 2024 Score 79

    …calcification on one hand and non-alcoholic fatty liver disease (NAFLD) on…

    ActiTest FibroTest NashTest SteatoTest +1

  62. Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.

    de Lédinghen V et al. · Liver Int · 2012 Score 79

    …simultaneously, enlarging the spectrum of non-invasive techniques for the management of…

    SteatoTest Metabolic

  63. Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.

    Vermehren J et al. · BMC Gastroenterol · 2012 Score 79

    …HIV-infected individuals based on non-invasive fibrosis assessment using transient elastography…

    FibroTest HCV HIV

  64. EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication

    European Association for Study of Liver et al. · J Hepatol · 2015 Score 78

    FibroTest Alcohol HBV HCV +3

  65. Role of leisure-time physical activity in nonalcoholic fatty liver disease: a population-based study.

    Zelber-Sagi S et al. · Hepatology · 2008 Score 78

    ### Unlabelled Physical activity (PA) is commonly recommended for nonalchoholic fatty liver disease…

    SteatoTest Metabolic

  66. The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.

    Sebastiani G et al. · Aliment Pharmacol Ther · 2011 Score 77

    …In HBV and non-alcoholic steatohepatitis (NASH) patients, its performance was poor…

    FibroTest HBV HCV HIV +1

  67. [The prevalence of liver and gallbladder pathologies in overweight and obese patients].

    Popova IR et al. · Klin Med (Mosk) · 2012 Score 77

    Non-alcoholic steatohepatitis was foumnd in 6.74% of the overweight patients…

    ActiTest FibroTest NashTest SteatoTest +1

  68. Novel Biomarkers of Grade I Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease.

    Braha A et al. · J Clin Med · 2024 Score 77

    …Although the underlying mechanisms remain unclear, innovative non-invasive biomarkers, such as…

    FibroTest Metabolic

  69. Evolution of Non-alcoholic Fatty Liver Disease (NAFLD) Biomarkers in Response to Weight Loss 1 Year After Bariatric Surgery-a Post Hoc Analysis of the FibroTest Prospective Study. Key publication

    Codjia T et al. · Obes Surg · 2021 Score 76

    ### Background Bariatric surgery is among the therapeutic options for non-alcoholic fatty…

    FibroTest NashTest SteatoTest Metabolic

  70. Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.

    Adams LA et al. · J Gastroenterol Hepatol · 2011 Score 76

    non-alcoholic fatty liver disease (NAFLD); however, it remains unclear whether non

    FibroTest Metabolic

  71. Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes. Key publication

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2020 Score 76

    ### Objective There is a controversy about the performance of blood tests for…

    FibroTest NashTest-2 SteatoTest-2 Metabolic

  72. Noninvasive Assessment of Liver Fibrosis. Key publication Review

    Castera L et al. · N Engl J Med · 2025 Score 75

    FibroTest Metabolic

  73. HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.

    Steininger K et al. · J Viral Hepat · 2017 Score 75

    …Liver-related and non-liver-related outcomes were documented. Overall 213 episodes…

    FibroTest HCV HIV

  74. Real-world efficacy and safety of ombitasvir, paritaprevir/r+dasabuvir+ribavirin in genotype 1b patients with hepatitis C virus cirrhosis.

    Preda CM et al. · Liver Int · 2018 Score 75

    ### Background Direct antiviral agents (DAA) showed very good results in terms of…

    FibroTest HCV

  75. An Invisible Early Steatosis Phenotype Defined for a Large Population-Based Cohort.

    Poynard T et al. · Biomedicines · 2025 Score 74

    **Background:** The current definition of metabolic dysfunction-associated steatotic liver disease (MASLD…

    FibroTest NashTest-2 SteatoTest-2 Metabolic

  76. Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.

    López Tórrez SM et al. · Front Nutr · 2024 Score 74

    …fibrosis index-4 (FIB-4), non-alcoholic fatty liver disease fibrosis score…

    FibroTest Metabolic

  77. Diagnostic value of serum protein profiling by SELDI-TOF ProteinChip compared with a biochemical marker, FibroTest, for the diagnosis of advanced fibrosis in patients with chronic hepatitis C.

    Morra R et al. · Aliment Pharmacol Ther · 2007 Score 74

    ### Background FibroTest has been validated for the diagnosis of liver fibrosis in…

    FibroTest Alcohol HBV HCV +1

  78. Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.

    Zelber-Sagi S et al. · World J Gastroenterol · 2013 Score 73

    ### Aim To compare noninvasive methods presently used for steatosis detection and quantification…

    SteatoTest Metabolic

  79. PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.

    Petit JM et al. · Liver Int · 2011 Score 73

    …fibrosis was measured using the non-invasive FibroTest(®). ### Results Advanced liver fibrosis…

    FibroTest Metabolic

  80. Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.

    Sebastiani G et al. · Can J Gastroenterol Hepatol · 2014 Score 72

    ### Objective To determine practices among physicians in Canada for the assessment of…

    FibroTest Alcohol HBV HCV +3

  81. The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B.

    Mallet V et al. · Aliment Pharmacol Ther · 2009 Score 72

    ### Background The Fib-4 index is a simple and inexpensive biomarker to…

    FibroTest HBV

  82. Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.

    Perazzo H et al. · Aliment Pharmacol Ther · 2014 Score 72

    ### Background In cardiometabolic disorders, non-alcoholic fatty liver disease is frequent and…

    FibroTest SteatoTest Metabolic

  83. Non-invasive markers for hepatic fibrosis. Review

    Baranova A et al. · BMC Gastroenterol · 2011 Score 71

    …However, the problem of the development of biomarkers capable of non-invasive…

    FibroTest Alcohol HBV HCV +3

  84. Contribution of the ELFG test in algorithms of non-invasive markers towards the diagnosis of significant fibrosis in chronic hepatitis C.

    Zarski JP et al. · PLoS One · 2013 Score 71

    ### Background And Aims We aimed to determine the best algorithms for the…

    FibroTest HCV

  85. The diagnostic performance of a simplified blood test (SteatoTest-2) for the prediction of liver steatosis. Key publication

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2019 Score 71

    ### Background Serum biomarkers of steatosis such as the SteatoTest are recommended for…

    NashTest-2 SteatoTest-2 Metabolic

  86. Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference. Key publication

    Munteanu M et al. · Aliment Pharmacol Ther · 2016 Score 70

    …are less well validated in non-alcoholic fatty liver disease (NAFLD) than…

    ActiTest FibroTest SteatoTest Metabolic

  87. Response to: Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications, by Jerome Boursier et al.

    Poynard T et al. · Clin Gastroenterol Hepatol · 2023 Score 70

    FibroTest Metabolic

  88. Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.

    Salles N et al. · Gastroenterol Clin Biol · 2009 Score 70

    …to evaluate liver fibrosis using non-invasive methods in elderly patients. ### Methods…

    FibroTest Metabolic

  89. Prediction for steatosis in type-2 diabetes: clinico-biological markers versus 1H-MR spectroscopy.

    Guiu B et al. · Eur Radiol · 2012 Score 69

    ### Objectives The SteatoTest, fatty liver index (FLI) and hepatic steatosis index (HSI…

    SteatoTest Metabolic

  90. Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.

    Fierbinteanu-Braticevici C et al. · World J Gastroenterol · 2009 Score 69

    ### Aim To investigate the diagnostic accuracy of acoustic radiation force impulse (ARFI…

    FibroTest HCV

  91. Altered serum N-glycomics in chronic hepatitis B patients.

    Gui HL et al. · Liver Int · 2010 Score 69

    …advanced fibrosis (F3-F6) from non- or mild fibrosis (F0-F2). However…

    FibroTest HBV

  92. Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.

    de Lédinghen V et al. · Dig Liver Dis · 2012 Score 68

    …hospitalized for their diabetes, using non-invasive methods, and to evaluate factors…

    FibroTest Metabolic

  93. Impact of quality control accepted inter-laboratory variations on calculated Fibrotest/Actitest scores for the non-invasive biochemical assessment of liver fibrosis.

    Gressner OA et al. · Clin Chim Acta · 2009 Score 68

    ### Introduction Non-invasive, i.e. serum-based assessment of liver fibrosis is…

    ActiTest FibroTest HCV

  94. Impact of steatosis and inflammation definitions on the performance of NASH tests.

    Poynard T et al. · Eur J Gastroenterol Hepatol · 2018 Score 68

    …a simpler histological definition of non-alcoholo steato-hepatitis (NASH), which does…

    ActiTest FibroTest NashTest NashTest-2 +3

  95. Long-term prognostic value of the FibroTest in patients with non-alcoholic fatty liver disease, compared to chronic hepatitis C, B, and alcoholic liver disease. Key publication

    Munteanu M et al. · Aliment Pharmacol Ther · 2018 Score 67

    …the stage of fibrosis in non-alcoholic fatty liver disease (NAFLD) with…

    FibroTest Alcohol HBV HCV +1

  96. Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.

    Rubio A et al. · J Pediatr Gastroenterol Nutr · 2009 Score 67

    …nucleoside reverse transcriptase inhibitor and non-nucleoside reverse transcriptase inhibitor drugs were…

    FibroTest HIV

  97. Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests.

    Nguyen-Khac E et al. · Aliment Pharmacol Ther · 2008 Score 66

    …seven non-invasive laboratory tests. ### Methods One hundred and three alcoholic patients…

    FibroTest Alcohol

  98. Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease. Key publication

    Thiele M et al. · Gastroenterology · 2018 Score 66

    …advanced fibrosis in patients with alcoholic liver disease recruited from primary and…

    FibroTest Alcohol

  99. The non-invasive assessment of hepatic fibrosis. Review

    Gheorghe G et al. · J Formos Med Assoc · 2021 Score 66

    …Research studies conducted in the last few years focused on identifying non

    ActiTest FibroTest Alcohol HBV +2

  100. [Prognosis assessment of alcoholic liver disease: how and why?]. Review

    Trabut JB et al. · Presse Med · 2014 Score 65

    …A validation of non-invasive methods for ALD could allow a large…

    FibroTest Alcohol

  101. Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV. Review

    Matta B et al. · Curr HIV/AIDS Rep · 2016 Score 65

    …Multiple non-invasive methods of liver fibrosis assessment have been developed, but…

    FibroTest HBV HCV HIV

  102. Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference. Key publication

    Peta V et al. · World J Hepatol · 2025 Score 65

    ActiTest FibroTest Autoimmune hepatitis

  103. Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.

    Ciećko-Michalska I et al. · Arch Med Sci Atheroscler Dis · 2018 Score 64

    …in abdominal ultrasound examination), using non-invasive tests: SteatoTest, ActiTest and FibroTest…

    ActiTest FibroTest SteatoTest Metabolic

  104. Noninvasive diagnosis in alcohol-related liver disease.

    Hadefi A et al. · Health Sci Rep · 2020 Score 64

    ### Background Alcohol-related liver disease (ALD) represents a major cause of death…

    FibroTest Alcohol

  105. Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study. Key publication

    Denimal D et al. · Cardiovasc Diabetol · 2025 Score 64

    …an independent relationship between a non-invasive liver fibrosis test and the…

    ActiTest FibroTest NashTest SteatoTest +1

  106. European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD) and European Association for the Study of Obesity (EASO) clinical practice recommendations for the management of non-alcoholic fatty liver disease: evaluation of their application in people with Type 2 diabetes.

    Sberna AL et al. · Diabet Med · 2018 Score 63

    …treatment and follow-up of non-alcoholic fatty liver disease in people…

    FibroTest NashTest Metabolic

  107. [Biomarkers for liver fibrosis: advances, advantages and disadvantages]. Review

    Cequera A et al. · Rev Gastroenterol Mex · 2014 Score 63

    …There is great interest in determining non-invasive markers for the diagnosis…

    FibroTest HCV

  108. Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.

    Laharie D et al. · J Hepatol · 2010 Score 63

    …the risk of liver fibrosis. Non-invasive methods for the diagnosis of…

    FibroTest Other

  109. Noninvasive Assessment of Liver Fibrosis.

    Castera L · Dig Dis · 2015 Score 62

    ### Background The prognosis and management of chronic liver diseases greatly depend on…

    FibroTest HBV HCV

  110. Liver fibrosis markers in alcoholic liver disease. Review

    Chrostek L et al. · World J Gastroenterol · 2014 Score 62

    …The assessment of the degree of liver fibrosis in alcoholic liver disease…

    FibroTest Alcohol

  111. Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.

    Vermehren J et al. · Liver Int · 2012 Score 61

    ### Background Acoustic radiation force impulse (ARFI) imaging is a new non-invasive…

    FibroTest Alcohol HBV HCV +3

  112. ActiTest accuracy for the assessment of histological activity grades in patients with chronic hepatitis C, an overview using Obuchowski measure. Meta Analysis

    Poynard T et al. · Gastroenterol Clin Biol · 2010 Score 61

    …73-0.85) and in non independent studies AUROC=0.74 (95…

    ActiTest HCV

  113. Liver stiffness measurement in children using FibroScan: feasibility study and comparison with Fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy.

    de Lédinghen V et al. · J Pediatr Gastroenterol Nutr · 2007 Score 61

    ### Objective Transient elastography (FibroScan) is a novel, noninvasive, rapid bedside method to…

    FibroTest HBV HCV Other

  114. HCV-GenoFibrotest: a combination of viral, liver and genomic (IL28b, ITPA, UGT1A1) biomarkers for predicting treatment response in patients with chronic hepatitis C.

    Costa JM et al. · Clin Res Hepatol Gastroenterol · 2011 Score 60

    ### Background And Aim Three gene polymorphisms, interferon-lambda-3 (IL28B), inosinetriphosphatase (ITPA…

    ActiTest FibroTest HCV-GenoFibroTest SteatoTest +1

  115. Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.

    Friedrich-Rust M et al. · Ultraschall Med · 2009 Score 60

    ### Purpose Transient elastography (FibroScan, [TE]) and serum fibrosis markers such as the…

    FibroTest Alcohol HBV HCV +2

  116. Intra-individual fasting versus postprandial variation of biochemical markers of liver fibrosis (FibroTest) and activity (ActiTest).

    Munteanu M et al. · Comp Hepatol · 2004 Score 60

    BACKGROUND: Biochemical marker combinations, including alpha2-macroglobulin, haptoglobin, apolipoprotein A1, gamma-glutamyl…

    ActiTest FibroTest Alcohol HBV +3

  117. Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data. Meta Analysis

    Poynard T et al. · PLoS One · 2012 Score 59

    …the gold standard for assessing non-alcoholic fatty liver disease (NAFLD) histologic…

    ActiTest FibroTest NashTest SteatoTest +1

  118. Concordance in a world without a gold standard: a new non-invasive methodology for improving accuracy of fibrosis markers.

    Poynard T et al. · PLoS One · 2008 Score 59

    …biopsy, an imperfect gold standard. Non-invasive techniques, liver stiffness measurements (LSM…

    FibroTest Alcohol HBV HCV +3

  119. Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.

    Więcek S et al. · Mediators Inflamm · 2020 Score 59

    Changes in the liver and bile ducts observed in patients diagnosed with…

    ActiTest FibroTest Other

  120. The diagnostic value of combining carbohydrate-deficient transferrin, fibrosis, and steatosis biomarkers for the prediction of excessive alcohol consumption.

    Imbert-Bismut F et al. · Eur J Gastroenterol Hepatol · 2009 Score 58

    …97 with alcoholic liver disease (ALD), and 223 non-ALD, were included…

    FibroTest SteatoTest Alcohol

  121. Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.

    Boursier J et al. · Aliment Pharmacol Ther · 2014 Score 58

    ### Background Recent longitudinal studies have emphasised the prognostic value of noninvasive tests…

    FibroTest HCV

  122. The Diagnostic Value of FibroTest and Hepascore as Non-Invasive Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC).

    Cylwik B et al. · J Clin Med · 2023 Score 58

    …the diagnostic usefulness of two non-invasive, validated, and patented markers of…

    FibroTest Other

  123. Personalized management of cirrhosis by non-invasive tests of liver fibrosis. Review

    Wong GL et al. · Clin Mol Hepatol · 2015 Score 57

    …In recent years, the development of non-invasive tests of fibrosis allows…

    FibroTest Alcohol HBV HCV +1

  124. The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease. Key publication

    Thabut D et al. · J Hepatol · 2006 Score 57

    …a simple and non-invasive quantitative estimate of alcoholic hepatitis. The use…

    AshTest Alcohol

  125. LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis. Key publication

    Poynard T et al. · Aliment Pharmacol Ther · 2019 Score 57

    ### Background No blood test has been shown to be effective in the…

    LCR1 LCR2 Alcohol HBV +4

  126. Meta-analyses of FibroTest diagnostic value in chronic liver disease. Key publication Meta Analysis

    Poynard T et al. · BMC Gastroenterol · 2007 Score 56

    …chronic hepatitis B (CHB), alcoholic liver disease (ALD) and non-alcoholic fatty…

    FibroTest Alcohol HBV HCV +1

  127. FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC³ program.

    Poynard T et al. · J Hepatol · 2011 Score 56

    …assess FibroTest (FT), a validated non-invasive marker of fibrosis in treatment…

    FibroTest HCV

  128. Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.

    Beckebaum S et al. · Transplantation · 2010 Score 55

    …AUROCs for diagnosis of F> or =3 in HCV patients and non

    FibroTest Alcohol HBV HCV +2

  129. Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication

    Shiha G et al. · Hepatol Int · 2009 Score 55

    Liver fibrosis is a common pathway leading to cirrhosis, which is the…

    FibroTest SteatoTest HBV HCV +1

  130. Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.

    Boursier J et al. · Clin Gastroenterol Hepatol · 2023 Score 55

    ### Background & Aims Noninvasive tests (NITs) of liver fibrosis have been suggested to…

    FibroTest Metabolic

  131. Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C. Key publication

    Poynard T et al. · Clin Chem · 2004 Score 54

    ### Background The FibroTest and ActiTest are noninvasive biochemical markers of liver injury…

    ActiTest FibroTest HCV

  132. Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).

    Poynard T et al. · BMC Gastroenterol · 2010 Score 54

    …The attributable causes for confirmed fibrosis were both alcoholic and nonalcoholic fatty…

    FibroTest Alcohol HBV HCV +3

  133. Biomarkers for liver disease in urea cycle disorders.

    Nagamani SCS et al. · Mol Genet Metab · 2021 Score 54

    …Thus, we systematically evaluated the potential utility of several non-invasive biomarkers…

    ActiTest FibroTest Other

  134. Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.

    Stevenson M et al. · Health Technol Assess · 2012 Score 53

    …MEDLINE (from 1950 to January 2010), MEDLINE In-Process & Other Non-Indexed…

    FibroTest Alcohol

  135. Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.

    Khalaf N et al. · Clin Gastroenterol Hepatol · 2015 Score 53

    …more of caffeinated tea by non-coffee drinkers (adjusted odds ratio, 0…

    FibroTest HCV

  136. A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation. Review

    Ahmad W et al. · Virol J · 2011 Score 53

    …Different invasive and non invasive methods are applied to diagnose the disease…

    FibroTest HCV

  137. Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis. Review

    Brener S · Ont Health Technol Assess Ser · 2015 Score 52

    …virus, nonalcoholic fatty liver disease, alcoholic liver disease, or cholestatic diseases. The…

    Elasto-FibroTest FibroTest Alcohol HBV +3

  138. Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication

    AASLD/IDSA HCV Guidance Panel · Hepatology · 2015 Score 52

    ActiTest FibroTest HCV

  139. EASL Clinical Practice Guidelines: management of hepatitis C virus infection.

    European Association for the Study of the Liver · J Hepatol · 2011 Score 52

    ActiTest FibroTest HCV

  140. EASL clinical practice guidelines: Management of chronic hepatitis B virus infection.

    European Association For The Study Of The Liver · J Hepatol · 2012 Score 51

    ActiTest FibroTest HBV

  141. Prise en charge des personnes infectées par les virus de l’hépatite B ou de l’hépatite C — Rapport de recommandations 2014 Key publication

    Score 51

    FibroTest HBV HCV

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