Publicaciones científicas sobre los diagnósticos no invasivos de BioPredictive
Estudios revisados por pares que validan los diagnósticos por análisis de sangre de BioPredictive para enfermedades hepáticas — desde cohortes de desarrollo pioneras hasta metaanálisis a largo plazo.
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Coincidencias para
“Fatty liver index”
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Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.
…the SteatoTest; the fatty liver index (FLI); regular abdominal ultrasound (AUS); and…
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The product of triglycerides and glucose as biomarker for screening simple steatosis and NASH in asymptomatic women.
…As compared versus SteatoTest, NashTest, Fatty liver index, and Algorithm, the TyG…
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Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.
The diagnostic utilities of ultrasonography (US), fatty liver index (FLI) and an…
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Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.
…CAP was significantly correlated with SteatoTest, Fatty Liver Index (FLI), percentage of…
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Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.
…APRI), fibrosis index-4 (FIB-4), non-alcoholic fatty liver disease fibrosis…
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Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
…of liver morbidity and mortality in non-alcoholic fatty liver disease (NAFLD…
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Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers. Review
…of non-alcoholic fatty liver disease (NAFLD). Since liver biopsy is invasive…
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Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods. Review
### Background Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of…
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Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population.
…Fatty liver was diagnosed with abdominal ultrasound and liver steatosis was quantified…
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European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD) and European Association for the Study of Obesity (EASO) clinical practice recommendations for the management of non-alcoholic fatty liver disease: evaluation of their application in people with Type 2 diabetes.
…Liver fat content (assessed using proton magnetic resonance spectroscopy), fatty liver index…
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Silymarin in non alcoholic fatty liver disease.
…silybum marianum on non alcoholic fatty liver disease (NAFLD). ### Methods In 72…
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Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials.
…risk factor for non-alcoholic fatty liver disease (NAFLD) occurrence and progression…
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Noninvasive Markers of Improvement of Liver Steatosis Achieved by Weight Reduction in Patients with Nonalcoholic Fatty Liver Disease.
### Unlabelled Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance…
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PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.
…mass index (BMI) and LFC were not associated with liver fibrosis. ### Conclusions…
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Prediction for steatosis in type-2 diabetes: clinico-biological markers versus 1H-MR spectroscopy.
### Objectives The SteatoTest, fatty liver index (FLI) and hepatic steatosis index (HSI…
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Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.
Nonalcoholic fatty liver disease (NAFLD) is dramatically increasing in parallel with the…
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The non-invasive assessment of hepatic fibrosis. Review
…Liver fibrosis, as the last stage of numerous chronic liver diseases, is…
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Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease.
Nonalcoholic fatty liver disease (NAFLD) is independently linked to cardiometabolic morbidity and…
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Noninvasive evaluation of NAFLD. Review
…developing complications of end-stage liver disease. Although it lacks sensitivity, ultrasonography…
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Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.
…potential contributing factor for nonalcoholic fatty liver disease (NAFLD). NAFLD severity and…
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Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus.
…those patients with non-alcoholic fatty liver disease (NAFLD) by ^1^H…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV. Review
Patients with HIV have a proclivity to develop liver fibrosis, especially when…
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Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes. Key publication
…The secondary aim was to construct an index (SpectrumF3F4-Index) to predict…
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Knowledge and practice regarding the German and the EASL-EASD-EASO NAFLD-guidelines among members of the German Obesity Society.
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The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
### Background Nonalcoholic fatty liver disease (NAFLD) is common in bariatric surgery candidates…
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Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
…factors of liver disease, such as non-alcoholic fatty liver disease, hazardous…
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Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
…index was 80%, 83%, and 69%, and for the diagnosis of liver…
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Noninvasive Assessment of Liver Fibrosis. Key publication Review
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Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
### Background HIV-monoinfected individuals are at high risk of nonalcoholic fatty liver…
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Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts. Key publication
…one hand and non-alcoholic fatty liver disease (NAFLD) on the other…
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Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease. Key publication
### Background & Aims Alcohol is the leading cause of cirrhosis and liver-related…
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Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
### Background In cardiometabolic disorders, non-alcoholic fatty liver disease is frequent and…
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Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study. Key publication
…Beyond its utility in assessing liver fibrosis, the FibroTest® could be a…
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Non-invasive markers for hepatic fibrosis. Review
…The rate of adoption of non-invasive diagnostic tests for liver fibrosis…
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Role of leisure-time physical activity in nonalcoholic fatty liver disease: a population-based study.
### Unlabelled Physical activity (PA) is commonly recommended for nonalchoholic fatty liver disease…
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Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication
…histologic lesions of non-alcoholic fatty liver disease (NAFLD). The aim was…
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Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication Review
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Liver fibrosis markers in alcoholic liver disease. Review
Alcohol is one of the main factors of liver damage. The evaluation…
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Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study.
…abdominal ultrasonography, liver biopsy, calculation of body mass index, and biomarker parameters…
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis. Review
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
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Biomarkers of liver fibrosis. Review
…C virus (HCV), hepatitis B virus (HBV), hepatitis nonalcoholic fatty liver disease…
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Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics.
…of liver fibrosis in alcoholic patients seems to be the Forns index.
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Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
Traditionally a disease of hepatologists, nonalcoholic fatty liver disease (NAFLD) has recently…
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Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. Review
…Fatty liver develops in more than 90% of heavy drinkers, however only…
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Study of FibroTest and hyaluronic acid biological variation in healthy volunteers and comparison of serum hyaluronic acid biological variation between chronic liver diseases of different etiology and fibrotic stage using confidence intervals.
…and F3 liver fibrosis stages in non-alcoholic fatty liver disease with…
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Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
### Introduction Identifying liver fibrosis is important to evaluate the severity of liver…
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Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases.
…Children present severe fatty liver disease with early cirrhosis. Before enzyme replacement…
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Assessment of liver fibrosis: noninvasive means.
…alcoholic (NAFLD) and alcoholic (ALD) fatty liver diseases. This review summarizes the…
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Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
…index, ultrasound, and Fibroscan. ### Results : Nineteen (>60%) children had signs of liver…
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EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
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The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…APRI, Forns'index, Lok index, AST-to-ALT ratio, Fib-4, platelets…
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Hepatotoxicity of tocilizumab and anakinra in rheumatoid arthritis: management decisions.
### Background Elevation of liver enzymes in rheumatoid arthritis patients treated with tocilizumab…
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Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
Changes in the liver and bile ducts observed in patients diagnosed with…
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Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference. Key publication
…ActiTest, FIB4, BARD, and nonalcoholic fatty liver disease scores. A combination of…
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Novel Biomarkers of Grade I Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease.
…and metabolic-dysfunction-associated steatotic liver disease (MASLD); however, the underlying mechanisms…
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Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
### Background Patients with diabetes are at risk for nonalcoholic fatty liver disease…
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Screening for liver fibrosis by using a noninvasive biomarker in patients with diabetes.
### Background & Aims Patients with diabetes are at risk for nonalcoholic fatty liver…
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Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.
…fatty liver disease with liver biopsy, blood fibrosis tests (Nonalcoholic Fatty Liver…
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The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
…ELF, ≥10.43; Nonalcoholic Fatty Liver Disease Fibrosis Score, ≥1.80; Fibrotest…
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Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.
…liver fibrosis (FibroScan) > or = 9.5 kPa). A body mass index greater…
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FibroMAX: towards a new universal biomarker of liver disease? Review
Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…
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FibroTest-FibroSURE: towards a universal biomarker of liver fibrosis?
Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…
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Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
…Routine assessment of liver fibrosis was requested by the surveyed physicians mostly…
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EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease.
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
### Background And Aim Mortality of alcohol-related liver disease (ArLD) is increasing…
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The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
…On univariate analysis body mass index (r = 0.40, P = .005) and…
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Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.
…CHB and its consequences on liver injury compared with CHC and NAFLD…
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Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). Key publication
…2-diabetes (T2D), obesity, and liver fibrosis (resmetirom) announce the widespread use…
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Diagnostic value of serum protein profiling by SELDI-TOF ProteinChip compared with a biochemical marker, FibroTest, for the diagnosis of advanced fibrosis in patients with chronic hepatitis C.
### Background FibroTest has been validated for the diagnosis of liver fibrosis in…
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Dietary vitamin E and C intake is inversely associated with the severity of nonalcoholic fatty liver disease.
### Background & Aims Although antioxidants have a protective potential in nonalcoholic fatty liver…
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Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients.
### Unlabelled Nonalcoholic fatty liver disease (NAFLD) is highly prevalent and being overweight…
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Acoustic Radiation Force Impulse Imaging for Diagnosis and Monitoring of Liver Fibrosis in Patients with Hepatitis C: A Review of Diagnostic Accuracy, Clinical Effectiveness, Cost-Effectiveness, and Guidelines Review
…This also allows for a sonographic evaluation of the liver to be…
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Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis. Key publication
### Background No prospective diagnostic studies have directly compared widespread non-invasive liver…
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Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis. Review
…B virus, nonalcoholic fatty liver disease, alcoholic liver disease, or cholestatic diseases…
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Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication Review
…of non-invasive biomarkers in liver fibrosis. A scoring system has been…
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Screening for Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Advanced Fibrosis in Diabetology: A Prospective Multicenter Study.
…AF risk stratification was determined by a composite criterion of liver biopsy…
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Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.
…Histologic staging of liver fibrosis served as the reference standard. ### Results Liver…
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Screening for liver disease using non-invasive biomarkers (FibroTest, SteatoTest and NashTest) in patients with hyperlipidaemia.
…It is impossible to perform liver biopsy in such a large number…
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Noninvasive Testing for Nonalcoholic Steatohepatitis and Hepatic Fibrosis in Patients With Psoriasis Receiving Long-term Methotrexate Sodium Therapy.
…All patients in the cohort except 1 were managed without a liver…
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Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).
…were both alcoholic and nonalcoholic fatty liver disease (NAFLD) in 66%, NAFLD…
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Noninvasive Assessment of Liver Fibrosis.
### Background The prognosis and management of chronic liver diseases greatly depend on…
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Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
…standard for assessing non-alcoholic fatty liver disease (NAFLD) histologic lesions. The…
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The diagnostic performance of a simplified blood test (SteatoTest-2) for the prediction of liver steatosis. Key publication
### Background Serum biomarkers of steatosis such as the SteatoTest are recommended for…
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Pharmacotherapeutic efficacy on noninvasive fibrosis progression in nonalcoholic fatty liver disease: a systematic review and network meta-analysis. Meta Analysis
### Background Fibrosis impacts long-term outcomes among patients with nonalcoholic fatty liver…
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Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.
Chronic Obstructive Pulmonary Disease (COPD) and Non-Alcoholic Fatty Liver Disease (NAFLD…
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The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.
### Background And Aims Blood tests and liver stiffness evaluation (LSE) by ultrasonographic…
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A Single Test Combining Blood Markers and Elastography is More Accurate Than Other Fibrosis Tests in the Main Causes of Chronic Liver Diseases.
…liver fibrosis in chronic hepatitis C (CHC) and non-alcoholic fatty liver…
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An Invisible Early Steatosis Phenotype Defined for a Large Population-Based Cohort.
**Background:** The current definition of metabolic dysfunction-associated steatotic liver disease (MASLD…
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The predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and Forns index to noninvasively estimate fibrosis in hepatitis C and nonhepatitis C liver diseases.
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Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by FibroScan in non-alcoholic fatty liver disease.
…the liver-related prognosis in patients with non-alcoholic fatty liver disease…
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Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.
…FS, Fibrotest, FIB-4, aspartate aminotransferase to platelet ratio index (APRI), and…
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Editorial: FibroTest to predict liver-related mortality in NAFLD. Should this change the diagnostic algorithm in NAFLD?
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Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes. Key publication
…the prediction of non-alcoholic liver disease by non-invasive blood tests…
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The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication
…B, alcoholic liver disease, and non-alcoholic fatty liver disease, and were…
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Letter: FibroTest for staging fibrosis in non-alcoholic fatty liver disease - authors' reply.
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Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
…markers of liver fibrosis were the body mass index >28 kg/m…
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Noninvasive diagnosis in alcohol-related liver disease.
…chronic liver diseases such as viral hepatitis and nonalcoholic fatty liver disease…
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Biochemical and biophysical assessment of MTX-induced liver fibrosis in psoriasis patients: Fibrotest predicts the presence and Fibroscan predicts the absence of significant liver fibrosis.
…To monitor this serial liver biopsies were performed. The Fibroscan and the…
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Non-invasive assessment of liver fibrosis: are we ready?
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Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.
…Liver biopsy is considered as the gold standard for assessing nonalcoholic fatty…
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Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference. Key publication
…liver injury are less well validated in non-alcoholic fatty liver disease…
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Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
…risk for intestinal failure-associated liver disease (IFALD). The aim of the…
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[The prevalence of liver and gallbladder pathologies in overweight and obese patients].
…Nonalcoholic fatty liver disease was diagnosed using hepatic elastography and senrum markers…
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Impact of steatosis and inflammation definitions on the performance of NASH tests.
…the limitations of similar European (Fatty Liver Inhibition of Progression) and USA…
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Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
### Background Liver disease is the third leading cause of mortality in patients…
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Fibromax-based nonalcoholic fatty liver disease in chronic obstructive pulmonary disease patients with obstructive sleep apnea: Methodological considerations.
The relationship between nonalcoholic fatty liver disease (NAFLD) and obstructive sleep apnea…
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The diagnostic value of combining carbohydrate-deficient transferrin, fibrosis, and steatosis biomarkers for the prediction of excessive alcohol consumption.
…transferrin (CDT%), is confounded by liver disease severity. The aim was to…
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Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
### Background Liver fibrosis, now assessed by liver biopsy or using non-invasive…
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Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.
### Introduction Nonalcoholic fatty liver disease (NAFLD) is one of the most common…
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The risk of multiplying diagnostic combinations in the absence of a perfect gold standard for a fibrosis test.
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Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
…infection or non-HCV-related liver diseases. ### Methods And Results The optimal…
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Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV co-infected patients with chronic hepatitis.
…Serum levels of 25(OH)D3 were also significantly correlated with liver…
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Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection. Review
Chronic hepatitis B virus (HBV) infection is a major cause of liver…
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The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
…in order to avoid the liver biopsy currently used for selection of…
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Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
### Background And Aims Liver stiffness measurement (LSM) and FibroTest (FT) are frequently…
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Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.
…Histological features were assessed invasively by liver biopsy and noninvasively using FibroTest…
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Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…Liver biopsy may be used in patients with suspected ALD to confirm…
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Transient elastography alone and in combination with FibroTest® for the diagnosis of hepatic fibrosis in alcoholic liver disease.
### Background & Aims The reliability of transient elastography (TE) to assess liver fibrosis…
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Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy. Key publication
### Background The efficiency of transient elastography for the assessment of liver fibrosis…
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Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
### Background/Aims Non-invasive markers of liver fibrosis have recently been developed…
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Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.
As an alternative to liver biopsy, an index of five biochemical markers…
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A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation. Review
…Although, liver biopsy is still considered as gold standard to identify liver…
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Real-Time Shear Wave versus Transient Elastography for Predicting Fibrosis: Applicability, and Impact of Inflammation and Steatosis. A Non-Invasive Comparison.
…Other criteria, elasticity CV, body mass index and depth of measures were…
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Non-invasive diagnosis of hepatitis B virus-related cirrhosis. Review
…Liver biopsy is the reference standard for assessment of liver fibrosis. However…
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The Distribution of Liver Steatosis, Fibrosis, Steatohepatitis and Inflammation Activity in Alcoholics According to FibroMax Test.
### Background The diagnosis of alcoholic liver diseases is based on the history…
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Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis. Review
The limitations of liver biopsy (invasive procedure, sampling errors, inter-observer variability…
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Biomarkers as a first-line estimate of injury in chronic liver diseases: time for a moratorium on liver biopsy?
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Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
…Although ultrasound is still accepted as an initial screen for fatty liver…
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Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests.
### Background Systematic screening for liver fibrosis in heavy-drinking patients is a…
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Biomarkers for liver disease in urea cycle disorders.
…Liver disease in UCDs may be associated with hepatic inflammation, hepatic fibrosis…
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Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication
Liver fibrosis is a common pathway leading to cirrhosis, which is the…
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Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.
### Background Progression of recurrent hepatitis C is accelerated in liver transplant recipients…
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Glycogenic hepatopathy. Review
…GH or for differentiation of this situation from nonalcoholic fatty liver disease.
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication Meta Analysis
…CHB), alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD…
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Serum bile acid levels as a predictor for the severity of liver fibrosis in patients with chronic hepatitis C.
Serum bile acids (SBAs) are commonly elevated in cholestatic liver diseases, but…
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Response to: Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications, by Jerome Boursier et al.
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[Biomarkers for liver fibrosis: advances, advantages and disadvantages]. Review
Liver cirrhosis in Mexico is one of the most important causes of…
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Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.
…AshTest is an appropriate non-invasive alternative to transjugular liver biopsy.
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Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
…54 ± 11 years) with chronic liver disease and established cirrhosis were included…
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Prognostic value of liver fibrosis biomarkers: a meta-analysis.
…transaminase-platelet ratio index (APRI), FIB-4, and liver stiffness measurement by…
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Performance of Plasma Biomarkers and Diagnostic Panels for Nonalcoholic Steatohepatitis and Advanced Fibrosis in Patients With Type 2 Diabetes.
…nonalcoholic fatty liver disease (NAFLD) should be evaluated for liver fibrosis. However…
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Prospective noninvasive analysis of hepatic fibrosis in patients with Crohn's disease: correlation of transient elastography and laboratory-based markers.
…Established markers of fibrosis, namely, aspartate transaminase-to-platelet ratio index (APRI…
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
…mass index and co-infection with schistosomiasis may interfere with liver fibrosis…
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B. Meta Analysis
…FibroTest, aspartate aminotransferase-platelet ratio index (APRI), FIB4 or TE, with biopsy…
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Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C. Key publication
### Background The FibroTest and ActiTest are noninvasive biochemical markers of liver injury…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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Hepatoprotective Effect of Antrodia cinnamomea Mycelium in Patients with Nonalcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial.
### Objective Nonalcoholic steatohepatitis (NASH) has become a prominent liver disease in contemporary…
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Management of the patient with SVR. Review
…SVR benefits are well-recognized with reductions in rates of liver complications…
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Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
…management of patients with chronic liver disease. Non-invasive tests (NITs) have…
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A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.
### Background & Aims Nonalcoholic steatohepatitis (NASH) is a prevalent liver disease associated with…
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The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease. Key publication
…The use of AshTest may reduce the need for liver biopsy, and…
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Intra-individual fasting versus postprandial variation of biochemical markers of liver fibrosis (FibroTest) and activity (ActiTest).
…These consisted of 29 healthy volunteers and 35 patients with chronic liver…
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Progression of liver fibrosis among injection drug users with chronic hepatitis C.
…Baseline liver biopsies were obtained (1996-1998) on a random sample of…
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Clinical and genetic definition of serum bilirubin levels for the diagnosis of Gilbert syndrome and hypobilirubinemia.
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Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.
### Introduction Hepatitis C virus (HCV) is the major cause of chronic liver…
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness. Review
…In this case, liver biopsy is still required to properly assess liver…
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American Association for the Study of the Liver
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Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases.
…We aimed to verify whether monitoring by liver biopsy might be replaced…
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Racial differences in the association between adiposity measures and the risk of hepatitis C-related liver disease.
…To evaluate the association between anthropometric measurements and advanced liver disease in…
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First-line assessment of patients with chronic liver disease with non-invasive techniques and without recourse to liver biopsy.
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Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.
…of liver disease severity. ### Objective To compare the awareness of liver disease…
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Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference. Key publication
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Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication
…The impact of treatment with ADV vs placebo was assessed on liver…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
### Background Liver stiffness and non-invasive tests predict overall survival in chronic…
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Non-invasive Investigations for the Diagnosis of Fontan-Associated Liver Disease in Pediatric and Adult Fontan Patients.
Fontan-associated liver disease (FALD) is a serious complication related to the…
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Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
…The Enhanced Liver Fibrosis (ELF) test consists of an algorithm of three…
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Higher serum testosterone is associated with increased risk of advanced hepatitis C-related liver disease in males.
### Unlabelled Males have strikingly increased risk of advanced liver disease. However, the…
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Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
…to platelet ratio index, FIB-4), and analyzed liver biopsy samples. We…
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Reproducibility of blood tests of liver fibrosis in clinical practice.
### Objectives To evaluate the inter-laboratory reproducibility of blood test for liver…
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Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
…METAVIR F stages, body mass index, and platelet count were also independently…
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Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients.
…Further studies are needed to guide strategies for surveillance of liver disease…
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Correlation between liver biopsy and fibrotest in the evaluation of hepatic fibrosis in patients with chronic hepatitis C.
### Aim To assess the diagnostic value of Fibrotest in comparison with liver…
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Liver biopsy analysis has a low level of performance for diagnosis of intermediate stages of fibrosis.
…patients with chronic liver disease or normal liver tissue that surrounded tumors…
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Noninvasive assessment of hepatic fibrosis and necroinflammatory activity in Egyptian children with chronic hepatitis C virus infection using FibroTest and ActiTest.
…Liver biopsy, because of its limitations and risks, might be considered an…
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Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
### Background Liver fibrosis in human immunodeficiency virus (HIV)-infected individuals is mostly…
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[Alpha 2 macroglobulin immunoturbidimetric assays (DakoCytomation reagents) on Roche Diagnostic analysers (Modular P, Cobas Integra). Application to FibroTest-Actic-Test].
### Background Alpha2Macroglobulin (A2M) measure showed a revival since it was introduced into…
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Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver.
### Background The only way to diagnose nodular regenerative hyperplasia (NRH) is liver…
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Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.
### Background & Aims Data on liver fibrosis evolution and its involvement in liver…
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Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection
…to assess the stage of liver disease and eligibility for treatment; prioritize…
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External Validation of LCR1-LCR2, a Multivariable Hepatocellular Carcinoma Risk Calculator, in a Multiethnic Cohort of Patients With Chronic Hepatitis B. Key publication
### Background And Aims The liver cancer risk test (LCR1-LCR2) is a…
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Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.
…with chronic liver disease and either histological assessment of liver fibrosis (n…
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Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19. Key publication
In patients with non-alcoholic fatty liver disease (NAFLD) with or without…
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
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Performance of serum apolipoprotein-A1 as a sentinel of Covid-19. Key publication
…followed for a risk of liver fibrosis risk in the USA (212…
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FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis. Meta Analysis
### Objectives Extent of liver fibrosis is one of the most important factors…
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Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy.
…a Model for End-Stage Liver Disease score ≥ 10 (24% [14-37…
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Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
…Prevalence of significant liver-fibrosis assessed by TE, ARFI-right-liver-lobe…
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Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.
…these findings in women and in people with other chronic liver diseases.
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Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication
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An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
Chronic hepatitis C remains a significant medical and economic burden in Canada…
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FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC³ program.
### Background & Aims EPIC-3 is a prospective, international study that has demonstrated…
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Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.
### Background Liver biopsy is the reference standard for assessing liver fibrosis and…
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Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard.
…compared with FibroTest (FT) and liver stiffness measurement (LSM) by transient elastography…
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The Diagnostic Value of FibroTest and Hepascore as Non-Invasive Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC).
…All patients had a liver biopsy. The Hepascore and FibroTest were calculated…
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Validation of the Performance of A1HPV6, a Triage Blood Test for the Early Diagnosis and Prognosis of SARS-CoV-2 Infection.
### Background And Aims Apolipoprotein A1 (A1) and haptoglobin (HP) serum levels are…
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Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.
…better biomarkers of drug-induced-liver-injury (DILI). ### Aims We aimed to…
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External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV. Key publication
### Background & Aims The Liver Cancer Risk test algorithm (LCR1-LCR2) is a…
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Prise en charge des personnes infectées par les virus de l’hépatite B ou de l’hépatite C — Rapport de recommandations 2014 Key publication
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