Publicaciones científicas sobre los diagnósticos no invasivos de BioPredictive
Estudios revisados por pares que validan los diagnósticos por análisis de sangre de BioPredictive para enfermedades hepáticas — desde cohortes de desarrollo pioneras hasta metaanálisis a largo plazo.
328/435
Coincidencias para
“noninvasive methods”
-
Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
…noninvasive methods were mostly used for hepatitis C (63% versus 37% liver…
-
Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.
…FibroTest (FT) are established methods for the noninvasive staging of liver fibrosis…
-
Noninvasive Assessment of Liver Fibrosis.
…Noninvasive methods rely on two different but complementary approaches: a 'biological' approach…
-
Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
### Background In recent years noninvasive methods have been evaluated for the assessment…
-
Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.
### Aim To compare noninvasive methods presently used for steatosis detection and quantification…
-
Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.
…and was superior to other noninvasive methods (APRI Index, FibroMax) for staging…
-
Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis. Review
…Guidelines are now awaited for the use of noninvasive methods in clinical…
-
Comparison of transient elastography (FibroScan), FibroTest, APRI and two algorithms combining these non-invasive tests for liver fibrosis staging in HIV/HCV coinfected patients: ANRS CO13 HEPAVIH and FIBROSTIC collaboration.
### Objectives Combining noninvasive tests increases diagnostic accuracy for staging liver fibrosis in…
-
Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
…Many of its disadvantages have led to develop noninvasive methods to replace…
-
Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases.
…biopsy might be replaced by noninvasive methods and to identify factors associated…
-
Performance of noninvasive markers for liver fibrosis is reduced in chronic hepatitis C with normal transaminases.
…Few studies investigated noninvasive markers of liver fibrosis in hepatitis C virus…
-
Prospective noninvasive analysis of hepatic fibrosis in patients with Crohn's disease: correlation of transient elastography and laboratory-based markers.
…This study aimed to prospectively assess the potential of noninvasive markers for…
-
Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
…evaluate the diagnostic performance of noninvasive methods for the detection of CFLD…
-
Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.
…with chronic hepatitis B (CHB). ### Methods Consecutive patients with CHB who underwent…
-
Validation of Ten Noninvasive Diagnostic Models for Prediction of Liver Fibrosis in Patients with Chronic Hepatitis B.
…noninvasive models in a large cohort of Asian CHB patients. ### Methods The…
-
Noninvasive evaluation of NAFLD. Review
…Although noninvasive methods require further validation, they could be useful for selecting…
-
Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.
…C (CHC) patients. ### Materials And Methods Two hundred and sixteen treatment-naive…
-
Liver stiffness measurement in children using FibroScan: feasibility study and comparison with Fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy.
### Objective Transient elastography (FibroScan) is a novel, noninvasive, rapid bedside method to…
-
Noninvasive Assessment of Liver Fibrosis. Key publication Review
-
Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
…diagnostic accuracy of non-invasive methods for the assessment of liver fibrosis…
-
Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.
…Paris, France) is a novel, noninvasive, and rapid bedside method to assess…
-
Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
…we assessed the accuracy of noninvasive methods for their respective diagnosis: magnetic…
-
Current complications and challenges in nonalcoholic steatohepatitis screening and diagnosis. Review
…is liver biopsy; however, other noninvasive methods have been developed. In this…
-
Noninvasive assessment of hepatic fibrosis and necroinflammatory activity in Egyptian children with chronic hepatitis C virus infection using FibroTest and ActiTest.
…FT and AT are potential noninvasive methods for assessment of hepatic fibrosis…
-
Discordance between liver biopsy and FibroTest in assessing liver fibrosis in chronic hepatitis B.
…in Asian patients with CHB. ### Methods Consecutive patients with CHB who underwent…
-
Performance of Plasma Biomarkers and Diagnostic Panels for Nonalcoholic Steatohepatitis and Advanced Fibrosis in Patients With Type 2 Diabetes.
…However, the performance of noninvasive clinical models/scores and plasma biomarkers for…
-
Comparison of liver stiffness, fibrotest and liver biopsy for assessment of liver fibrosis in kidney-transplant patients with chronic viral hepatitis.
To assess the accuracy of the noninvasive tools, fibrotest (FT) and liver…
-
Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers.
…noninvasive staging of liver fibrosis in a multitude of studies. ### Methods A…
-
Serum bile acid levels as a predictor for the severity of liver fibrosis in patients with chronic hepatitis C.
…In addition, we assessed the accuracy of SBA levels as a noninvasive…
-
Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.
…Fibromax is a promising noninvasive diagnostic tool in family medicine for identifying…
-
[The value of noninvasive serological markers in hepatitis B]. Review
…us to conclude that noninvasive serological methods constitute a useful tool for…
-
Study on noninvasive laboratory tests for fibrosis in chronic HBV infection and their evaluation.
### Background Noninvasive laboratory tests have been widely used in the diagnosis of…
-
Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review. Review
…Currently, we observe rapid developments of non-invasive methods that are particularly…
-
A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation. Review
…patients. ### Methods More than 200 studies regarding invasive and noninvasive markers available…
-
SAFE biopsy: a validated method for large-scale staging of liver fibrosis in chronic hepatitis C.
…Although liver biopsy remains the gold standard, several noninvasive methods are under…
-
FibroScan and FibroTest to assess liver fibrosis in HCV with normal aminotransferases.
-
The non-invasive assessment of hepatic fibrosis. Review
…This narrative review presents the non-invasive investigation methods used in the…
-
Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy. Key publication
…LB) as the reference standard. ### Methods An unselected and consecutive group of…
-
Non-invasive diagnosis of hepatitis B virus-related cirrhosis. Review
…Such limitations have encouraged development of non-invasive methods for assessment of…
-
Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.
…Several methods have been proposed in patients with chronic hepatitis C (CHC…
-
Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.
…and inadequate description of enrollment methods. ### Conclusion Many blood tests are moderately…
-
Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.
### Background Noninvasive methods for liver fibrosis evaluation in chronic liver diseases have…
-
FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
### Aim To compare histological endpoint assessment using noninvasive alternatives to biopsy during…
-
Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
…regardless of the noninvasive method of analysis. All methods were able to…
-
[The scope of clinical applications of noninvasive methods for the assessment of liver fibrosis results of orginial studies in a multi-field hospital].
Potential and limitations of non-invasive methods for the evaluation of hepatic…
-
Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores.
…12.5 kPa), as compared with other available methods, but cannot replace…
-
EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
-
Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.
### Background & Aims Noninvasive tests (NITs) of liver fibrosis have been suggested to…
-
Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B. Meta Analysis
…To permit more appropriate comparisons. ### Methods From an overview of articles (2002…
-
FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis. Meta Analysis
…fibrosis. ### Methods MEDLINE and EMBASE searches and hand searching methods were performed…
-
Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.
…determine the diagnostic utility of noninvasive markers of fibrosis (FibroTest), steatosis (SteatoTest…
-
Comparison of FibroTest-ActiTest with histopathology in demonstrating fibrosis and necroinflammatory activity in chronic hepatitis B and C.
### Aims FibroTest and ActiTest are noninvasive tests used in determining the level…
-
Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.
…comparison with liver stiffness (LS). ### Methods From 2008 to 2010, 194 CHB…
-
Biomarkers of liver fibrosis. Review
Liver biopsy, due to its limitations and risks, is an imperfect gold…
-
FibroSURE as a noninvasive marker of liver fibrosis and inflammation in chronic hepatitis B.
### Background Noninvasive markers of liver fibrosis have not been extensively studied in…
-
Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
…for fatty liver diagnosis, new methods have recently been developed to detect…
-
Non-invasive diagnosis and follow-up of portal hypertension.
Compensated advanced chronic liver disease (cACLD) describes the spectrum of advanced fibrosis…
-
Validation of biochemical markers for the prediction of liver fibrosis and necroinflammatory activity in hemodialysis patients with chronic hepatitis C.
…with hepatitis C virus (HCV). ### Methods The FT-AT index combining 6…
-
The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B.
…index in chronic hepatitis B. ### Methods We compared the FIB-4 index…
-
Development and validation of a nomogram based on clinical factors and standard laboratory tests for prediction of clinically significant liver fibrosis in chronic hepatitis C virus infection.
…a widely used noninvasive fibrosis score. ### Materials And Methods Nomograms are graphical…
-
Diffusion-weighted magnetic resonance imaging for the assessment of fibrosis in chronic hepatitis C.
…We evaluated a noninvasive method, so-called diffusion-weighted magnetic resonance imaging…
-
Hepatitis B: are non-invasive markers of liver fibrosis reliable? Review
…Although these non-invasive methods were initially developed and validated in patients…
-
Transient elastography alone and in combination with FibroTest® for the diagnosis of hepatic fibrosis in alcoholic liver disease.
…or in combination with TE. ### Methods We conducted a multicentre prospective study…
-
Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C.
…combining them in sequential algorithms. ### Methods One hundred and ninety patients with…
-
Performance of 11 biomarkers for liver fibrosis assessment in HIV/HBV co-infected patients.
…in HIV/HBV co-infection. ### Methods Performance was evaluated using the Receiver…
-
FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest.
…hepatitis C virus (HCV) infection, noninvasive tests to determine the degree of…
-
Liver biopsy analysis has a low level of performance for diagnosis of intermediate stages of fibrosis.
### Background & Aims There is controversy about the performance of noninvasive tests such…
-
Noninvasive assessment of portal hypertension in patients with cirrhosis. Review
…Although most of these noninvasive methods effectively identify severe portal hypertension, methods…
-
Letter: FibroTest for staging fibrosis in non-alcoholic fatty liver disease.
-
Standardization of ROC curve areas for diagnostic evaluation of liver fibrosis markers based on prevalences of fibrosis stages. Key publication
…and to elaborate simple methods of standardization. ### Methods The AUCs of FibroTest…
-
Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
A serum biomarker (FibroTest; Biopredictive, Paris, France; FibroSure; LabCorp, Burlington, USA) and…
-
Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV. Review
…Multiple non-invasive methods of liver fibrosis assessment have been developed, but…
-
Acoustic Radiation Force Impulse Imaging for Diagnosis and Monitoring of Liver Fibrosis in Patients with Hepatitis C: A Review of Diagnostic Accuracy, Clinical Effectiveness, Cost-Effectiveness, and Guidelines Review
…ideal ‘one-stop shop’ for noninvasive liver evaluation, even in patients with…
-
Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.
…severity in people with MASLD. ### Methods Adults ≥18 years of age with…
-
Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.
…Noninvasive methods such as shear wave elastography and FibroTest may allow a…
-
The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
…for antiviral therapy. ### Patients And Methods A retrospective study was carried out…
-
Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
…survival in chronic hepatitis B. ### Methods In a consecutive cohort, we prospectively…
-
Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
…in liver biopsy. ### Material And Methods Galactose and methacetin breath tests (GBT…
-
Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods. Review
…the most accurate estimating methods are FibroMeter, FIB-4, NAFLD fibrosis score…
-
Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.
### Background Recent longitudinal studies have emphasised the prognostic value of noninvasive tests…
-
Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
…with liver fibrosis. ### Material And Methods 68 children with chronic liver disease…
-
Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
…complications in patients with cirrhosis. ### Methods A total of 166 patients (109…
-
Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver.
…performance of noninvasive liver investigations in patients with NRH. ### Methods All consecutive…
-
Assessment of liver fibrosis: noninvasive means.
Liver biopsy, owing to its limitations and risks, is an imperfect gold…
-
A novel panel of blood markers to assess the degree of liver fibrosis.
The objective was to develop new blood tests to characterize different fibrosis…
-
Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study.
…for noninvasive diagnosis of steatosis in patients with chronic HCV. ### Methods This…
-
The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…the performance of fibrosis biomarkers. ### Methods A total of 2411 patients with…
-
Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C. Review
…of severe fibrosis and cirrhosis. ### Methods The accuracy for severe fibrosis or…
-
The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
…using validated non-invasive measures. ### Methods Patients with morbid obesity and NAFLD…
-
FibroMAX: towards a new universal biomarker of liver disease? Review
Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…
-
Factors to improve the management of hepatitis C in drug users: an observational study in an addiction centre.
…by a multidisciplinary team and noninvasive liver fibrosis evaluation. A total of…
-
Discordance between biochemical markers of liver activity and fibrosis (Actitest-Fibrotest) and liver biopsy in patients with chronic hepatitis C.
…patients with chronic hepatitis C. ### Methods Routine blood tests, Actitest and Fibrotest…
-
Prediction of liver histological lesions with biochemical markers in patients with chronic hepatitis B.
…of noninvasive serum markers in patients with chronic hepatitis B. ### Methods The…
-
Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.
…chronic liver disease. ### Materials And Methods This study received ethics approval, and…
-
Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.
…need of non-invasive validated methods to estimate liver fibrosis. ### Aim To…
-
Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.
### Objective Fibroscan (FS) is a reliable noninvasive method for the diagnosis of…
-
Liver fibrosis in young Egyptian beta-thalassemia major patients: relation to hepatitis C virus and compliance with chelation.
…Non invasive Liver FibroScan and Fibro-Test were reliable methods to assess…
-
FibroTest and Fibroscan performances revisited in patients with chronic hepatitis C. Impact of the spectrum effect and the applicability rate.
…into account the applicability rates. ### Methods One thousand two hundred and eighty…
-
Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
…chronic hepatitis B (CHB) patients. ### Methods Between June 2010 and November 2011…
-
Screening for liver fibrosis by using a noninvasive biomarker in patients with diabetes.
…a noninvasive fibrosis biomarker (FibroTest) in patients with diabetes. ### Methods We prospectively…
-
The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
### Importance There is a need for noninvasive tools to monitor hepatotoxicity in…
-
Letter: FibroTest for staging fibrosis in non-alcoholic fatty liver disease - authors' reply.
-
Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
…a multi-centre NAFLD cohort. ### Methods Simple (APRI, BARD) and complex (Hepascore…
-
Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
…non-HCV-related liver diseases. ### Methods And Results The optimal TE cutoff…
-
FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy. Meta Analysis
…Due to the limitations of biopsy, noninvasive alternatives including FibroTest and FibroScan…
-
Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). Key publication
…This can be achieved if three essential but neglected STARD methods (3M…
-
Biochemical and biophysical assessment of MTX-induced liver fibrosis in psoriasis patients: Fibrotest predicts the presence and Fibroscan predicts the absence of significant liver fibrosis.
…The Fibroscan and the Fibrotest are two novel, non-invasive methods that…
-
Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasive.
…We aimed to evaluate successive SAFE, successive BA, and a new, noninvasive…
-
Transient elastography and biomarkers for liver fibrosis assessment and follow-up of inactive hepatitis B carriers.
### Background Non invasive methods for fibrosis evaluation remain to be validated longitudinally…
-
Spleen stiffness measurement by transient elastography to diagnose portal hypertension in children.
…invasive procedures such as endoscopy. Noninvasive tools to diagnose the presence and…
-
Comparison of elastography, serum marker scores, and histology for the assessment of liver fibrosis in hepatitis B virus (HBV)-infected patients in Burkina Faso.
…This study shows that the results of alternative methods concord with those…
-
Pharmacotherapeutic efficacy on noninvasive fibrosis progression in nonalcoholic fatty liver disease: a systematic review and network meta-analysis. Meta Analysis
…noninvasive testing over liver biopsy for the assessment of fibrosis. ### Methods A…
-
Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference. Key publication
…metabolic liver disease (MLD) by noninvasive tests (NITs). ### Objective The primary aim…
-
Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
…SBS receiving long-term PN. ### Methods Twenty-five adult patients with SBS…
-
Prognostic value of liver fibrosis biomarkers: a meta-analysis.
### Aims And Methods Several serum biomarkers such as FibroTest, aspartate transaminase-platelet…
-
Diagnostic accuracy of the Coopscore© to predict liver fibrosis in human immunodeficiency virus/hepatitis B virus co-infection.
Background Non-invasive methods for assessing liver fibrosis are increasingly used as…
-
Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B.
…The performance of these methods and of sequential algorithms combining Fibrotest, APRI…
-
Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
…radiation force impulse (ARFI) technology. ### Methods A cohort of 127 Taiwanese patients…
-
Variability in definitions of transaminase upper limit of the normal impacts the APRI performance as a biomarker of fibrosis in patients with chronic hepatitis C: "APRI c'est fini ?".
…stage due to necroinflammatory activity. ### Methods The variability of AST-ULN was…
-
A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C. Key publication
### Background FibroTest, a noninvasive method of measuring biomarkers of liver fibrosis, is…
-
Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication Review
…of time, in the meantime, methods can be improved. The main proposals…
-
Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
…direct comparison of both markers. ### Methods In the present study, the ELF…
-
Progression of liver fibrosis among injection drug users with chronic hepatitis C.
…further work is needed to find noninvasive markers of significant liver fibrosis.
-
Impact of steatosis and inflammation definitions on the performance of NASH tests.
…of metabolic liver disease by noninvasive tests. The construction of performant tests…
-
Non-invasive diagnosis and follow-up of chronic infection with Hepatitis C Virus.
…positive patients with non-invasive methods in screening, in assessing viral disease…
-
Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard.
…TE-M and TE-XL). ### Methods Without a gold standard, the strength…
-
Changes of non-invasive markers and FibroScan values during HCV treatment.
The recent advent of non-invasive methods for assessment of fibrosis allows…
-
Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness. Review
…Over the past decade, various non-invasive methods have been proposed to…
-
Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
…The aims of this study are to evaluate the feasibility of noninvasive…
-
Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.
…using non-invasive methods in elderly patients. ### Methods In a prospective two…
-
Liver fibrosis regression and progression during controlled hepatitis B virus infection among HIV-HBV patients treated with tenofovir disoproxil fumarate in France: a prospective cohort study.
…in TDF-treated coinfected patients. ### Methods In this prospective cohort study, 167…
-
Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference. Key publication
-
Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease. Key publication
…liver fibrosis (Kleiner stage ≥F3). ### Methods We performed a prospective study of…
-
Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
…imaging and fibrosis blood tests. ### Methods 106 patients with CF were prospectively…
-
Non-invasive fibrosis tests to predict complications in compensated post-hepatitis C cirrhosis.
…in noninvasive markers of fibrosis can predict liver-related complications. ### Methods This…
-
Screening for Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Advanced Fibrosis in Diabetology: A Prospective Multicenter Study.
…This study aimed to compare the performance of noninvasive tests (NITs) with…
-
Prevalence of liver fibrosis and cirrhosis in 699 Moroccan patients with chronic hepatitis C.
…complications in the Moroccan population. ### Methods the prevalence of liver fibrosis and…
-
Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.
### Background Effective antiviral treatment (direct-acting antiviral agents (DAAs)), the requirement for…
-
Evolution of Non-alcoholic Fatty Liver Disease (NAFLD) Biomarkers in Response to Weight Loss 1 Year After Bariatric Surgery-a Post Hoc Analysis of the FibroTest Prospective Study. Key publication
…year after surgery using noninvasive markers. ### Methods From November 2011 to November…
-
Non-invasive evaluation of the liver disease severity in children with chronic viral hepatitis using FibroTest and ActiTest - comparison with histopathological assessment.
…Further studies on non-invasive methods to evaluate liver disease severity in…
-
FIB-4: a simple, inexpensive and accurate marker of fibrosis in HCV-infected patients.
-
Non-invasive markers for hepatic fibrosis. Review
…The lack of accurate, reproducible and easily applied methods for fibrosis assessment…
-
Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
…and serum biomarkers (Fibrotest [FT]). ### Methods In 202 consecutive HIV-infected individuals…
-
Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection. Review
…This review outlines the methods of fibrosis assessment in chronic HBV infection…
-
Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.
…by METAVIR) and cirrhosis (F4). ### Methods A total of 1013 HCV monoinfected…
-
Longitudinal assessment of histology surrogate markers (FibroTest-ActiTest) during lamivudine therapy in patients with chronic hepatitis B infection.
### Objectives The noninvasive serum markers, FibroTest-ActiTest (FT-AT), are an alternative…
-
Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis. Review
…and steatosis is biopsy, but noninvasive alternatives are available; one of the…
-
Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
…2 diabetes and/or dyslipidaemia. ### Methods A total of 2312 patients with…
-
Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.
…in HIV-HCV-coinfected patients. ### Methods We included 114 HIV-HCV-coinfected…
-
Comparison of test performance profile for blood tests of liver fibrosis in chronic hepatitis C.
…blood tests of liver fibrosis. ### Methods Three hundred and fifty-six patients…
-
Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases.
…ALT)], fibrosis stage and surrogate noninvasive markers of fibrosis (APRI, FORNS, FibroTest…
-
Biopsy as well as FibroTest/Fibrosure is suboptimal for discriminating intermediate fibrosis stages in patients with chronic hepatitis B.
-
Analytical variability of the Fibrotest proteins.
…the FT proteins. ### Design And Methods During the FIBROPACA study, we evaluated…
-
Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics.
…The values of noninvasive markers were calculated with specific algorithms. The fibrosis…
-
Non-invasive assessment of liver fibrosis: are we ready?
-
The diagnostic performance of a simplified blood test (SteatoTest-2) for the prediction of liver steatosis. Key publication
…or hemolysis, respectively. ### Patients And Methods Five different subsets of 2997 patients…
-
Comparison of Fibrotest and PGAA for the diagnosis of fibrosis stage in patients with alcoholic liver disease.
…their diagnostic performances. ### Patients And Methods We prospectively included 200 consecutive patients…
-
Altered serum N-glycomics in chronic hepatitis B patients.
…with chronic hepatitis B infection. ### Methods Patients with hepatitis B virus (HBV…
-
Biomarkers for the prediction of liver fibrosis in patients with chronic alcoholic liver disease.
…noninvasive markers of fibrosis in patients with chronic alcoholic liver disease. ### Methods…
-
The diagnostic value of combining carbohydrate-deficient transferrin, fibrosis, and steatosis biomarkers for the prediction of excessive alcohol consumption.
…using biomarkers FibroTest and SteatoTest. ### Methods Three hundred and twenty consecutive patients…
-
The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
…We assessed the associations between histologic and noninvasive tests (NITs) for fibrosis…
-
Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.
…clinical usability in clinical practice. Methods In this prospective study, 63 CHC…
-
Validation of liver fibrosis biomarker (FibroTest) for assessing liver fibrosis progression: proof of concept and first application in a large population.
…to a large population (P2). ### Methods In P1, LFP was assessed using…
-
Impact of quality control accepted inter-laboratory variations on calculated Fibrotest/Actitest scores for the non-invasive biochemical assessment of liver fibrosis.
…and grading of liver fibrosis. ### Methods (i) Haptoglobin, ALT, gamma GT, alpha…
-
An Invisible Early Steatosis Phenotype Defined for a Large Population-Based Cohort.
…grade using large population cohorts. **Methods:** We assessed the prevalence of the…
-
Commentary: prognostication of chronic hepatitis B - are Fibrotest and Fibroscan the final answers? Authors' reply.
-
Diagnostic value of FibroTest with normal serum aminotransferases.
-
Biochemical markers of liver fibrosis: a comparison with historical features in patients with chronic hepatitis C.
…Several noninvasive biochemical markers are highly predictive for the discrimination of significant…
-
Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: the fibrovic study--ANRS HC02.
…HIV/HCV co-infected patients. ### Methods Two hundred and seventy-two HIV…
-
Non-invasive Investigations for the Diagnosis of Fontan-Associated Liver Disease in Pediatric and Adult Fontan Patients.
Fontan-associated liver disease (FALD) is a serious complication related to the…
-
Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases.
…Liver histology was assessed by the noninvasive tests FibroScan and FibroTest and…
-
[The prediction and validation of liver fibrosis by a noninvasive model and validation in patients with chronic hepatitis B].
### Objective To develop a simple model for the noninvasive diagnosis of liver…
-
The new paradigm of hepatitis C therapy: integration of oral therapies into best practices. Review
…Assessments of histologic damage typically are performed using liver biopsy, yet noninvasive…
-
Comparison of liver fibrosis blood tests developed for HCV with new specific tests in HIV/HCV co-infection.
…in HCV/HIV co-infection. ### Methods Four hundred and sixty-seven patients…
-
Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes. Key publication
…spectrum effect by Obuchowski measure. ### Methods Data were retrospectively compared among patients…
-
Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication
…FibroTest-ActiTest (FT-AT) as noninvasive markers of histological changes in patients…
-
Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomics.
We applied our 'clinical glycomics' technology, based on DNA sequencer/fragment analyzers…
-
The Distribution of Liver Steatosis, Fibrosis, Steatohepatitis and Inflammation Activity in Alcoholics According to FibroMax Test.
…means of FibroMax. ### Material And Methods A total of 142 consecutive alcoholics…
-
Contribution of the ELFG test in algorithms of non-invasive markers towards the diagnosis of significant fibrosis in chronic hepatitis C.
…parameters and tests. ### Patients And Methods We used the database from our…
-
Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
…with cystic fibrosis. _Material and Methods_. The study included 79 patients with…
-
The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.
…liver biopsy requirement in algorithm. ### Methods Three hundred and ninety patients with…
-
Screening studies of transient elastography and FibroTest in the general population - Authors' reply.
-
Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.
…liver biopsy, in untreated patients with chronic hepatitis C (CHC). ### Methods This…
-
FibroTest is effective in patients with normal transaminases, when accuracy is standardized on fibrosis stage prevalence.
-
Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.
…normal alanine aminotransferase (ALT) values. ### Methods LSM and liver fibrosis biochemical markers…
-
Improving estimation of liver fibrosis using combination and newer noninvasive biomarker scoring systems in hepatitis C-infected haemophilia patients.
Non-invasive biomarkers have gained popularity for estimating fibrosis stage. In our…
-
Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.
…effectiveness of treatment. ### Material And Methods We evaluated the intensity of steatosis…
-
Reproducibility of blood tests of liver fibrosis in clinical practice.
…FibroMeter, Fibrotest, APRI and their composites variables. ### Design And Methods Four studies…
-
Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.
Transient elastography (TE) is a noninvasive technique to evaluate liver fibrosis. We…
-
Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.
…transjugular biopsy before deciding treatment. ### Methods The reference was liver biopsy, performed…
-
Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.
…OSA population, including nonobese subjects. ### Methods Noninvasive blood tests (SteatoTest, NashTest, and…
-
Diagnostic accuracy of the fibrotest in hemodialysis and renal transplant patients with chronic hepatitis C virus.
…accuracy of the fibrotest (a noninvasive method to assess liver fibrosis in…
-
Is it possible to predict HCV-related liver cirrhosis non-invasively through routine laboratory parameters? Review
…evaluation and other non-invasive methods (fibroscan or fibrotest) on independent cohorts…
-
The effectiveness of noninvasive biomarkers to predict hepatitis B-related significant fibrosis and cirrhosis: a systematic review and meta-analysis of diagnostic test accuracy. Meta Analysis
Noninvasive biomarkers have been developed to predict hepatitis B virus (HBV)-related…
-
Fibrotest or Fibroscan for evaluation of liver fibrosis in haemophilia patients infected with hepatitis C.
…of fibrosis by non-invasive methods. Fifty-seven hepatitis C-infected haemophilia…
-
The predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and Forns index to noninvasively estimate fibrosis in hepatitis C and nonhepatitis C liver diseases.
-
Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?
…Biochemical markers seem particularly useful as a noninvasive alternative to liver biopsy…
-
Silymarin in non alcoholic fatty liver disease.
…alcoholic fatty liver disease (NAFLD). ### Methods In 72 patients affected by NAFLD…
-
Correlation between liver biopsy and fibrotest in the evaluation of hepatic fibrosis in patients with chronic hepatitis C.
…patients with chronic hepatitis C. ### Methods This prospective study included in 2…
-
Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. Review
Alcoholic liver disease (ALD) consists of a broad spectrum of disorders, ranging…
-
Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
…Hepascore, Forns' score and APRI). ### Methods We studied 180 chronic hepatitis C…
-
Optimized stepwise combination algorithms of non-invasive liver fibrosis scores including Hepascore in hepatitis C virus patients.
…algorithms to improve diagnostic accuracy. ### Methods The cohort included 467 patients with…
-
Relative performances of FibroTest, Fibroscan, and biopsy for the assessment of the stage of liver fibrosis in patients with chronic hepatitis C: a step toward the truth in the absence of a gold standard.
…FibroTest, LSM, and biopsy using methods without gold standard in patients with…
-
An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
Noninvasive markers that accurately follow changes in fibrosis may provide alternatives to…
-
Late presentation of chronic viral hepatitis for medical care: a consensus definition.
…situation on a population basis. ### Methods A working group including viral hepatitis…
-
Prediction for steatosis in type-2 diabetes: clinico-biological markers versus 1H-MR spectroscopy.
…type-2 diabetic (T2D) patients. ### Methods We enrolled 220 consecutive T2D patients…
-
Meta-analyses of FibroTest diagnostic value in chronic liver disease. Key publication Meta Analysis
…intermediate and extreme fibrosis stages. ### Methods The main end points were the…
-
[SWE elastography in assessment of liver fibrosis]. Review
…less or even non-invasive methods are being developed, e.g. using…
-
First-line assessment of patients with chronic liver disease with non-invasive techniques and without recourse to liver biopsy.
-
The risks of changing the rules for previously validated biomarkers and using the same patients several times. Response letter to Calès et al. Gastroenterol Clin Biol 2008;32:1050-60: "Evaluation and improvement of a reliable diagnosis of cirrhosis by blood tests".
-
Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data. Meta Analysis
…NashTest, ActiTest) in these patients. ### Methods 494 patients with interpretable biopsy and…
-
Noninvasive diagnosis in alcohol-related liver disease.
…Among the noninvasive surrogate markers and techniques used to detect liver fibrosis…
-
Biological markers of liver fibrosis and activity as non-invasive alternatives to liver biopsy in patients with chronic hepatitis C and associated mixed cryoglobulinemia vasculitis.
### Objective And Methods We assessed the reliability of non-invasive biological scoring…
-
An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load. Key publication
…of the inactive carrier status. ### Methods And Findings 1,300 consecutive CHB…
-
Biomarkers as a first-line estimate of injury in chronic liver diseases: time for a moratorium on liver biopsy?
-
Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
…invasive methods, and to evaluate factors associated with severe fibrosis. ### Methods Consecutive…
-
Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.
…coinfected patients undergoing tenofovir (TDF). ### Methods We included 169 HIV-HBV-coinfected…
-
Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).
…patients with sustained virological response. ### Methods The 10-year updated individual data…
-
Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
…FibroScan, and FibroTest) in ArLD. ### Methods Applying systematic review methodology, we searched…
-
Hepatitis B virus genotype G and liver fibrosis progression in chronic hepatitis B and human immunodeficiency virus coinfection.
…evolution remains to be established. ### Methods In this prospective cohort study, 158…
-
Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication Review
-
Successful treatment with telaprevir-based regimens for chronic hepatitis C results in significant improvements to serum markers of liver fibrosis.
…However, not all correlations observed between noninvasive markers and fibrosis stage at…
-
Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.
…compensated cirrhosis or advanced fibrosis. ### Methods This retrospective analysis included 501 patients…
-
An evaluation of the potential cost-effectiveness of non-invasive testing strategies in the diagnosis of significant liver fibrosis.
…2) compared with liver biopsy. ### Methods We developed a decision analytic model…
-
FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication Meta Analysis
FibroTest (FT) is a biomarker of liver fibrosis initially validated in patients…
-
Evaluating the accuracy and increasing the reliable diagnosis rate of blood tests for liver fibrosis in chronic hepatitis C.
…tests for significant liver fibrosis. ### Methods Five blood tests were compared with…
-
[Biomarkers for liver fibrosis: advances, advantages and disadvantages]. Review
…methods such as ultrasound and magnetic resonance elastography; some of the methods…
-
Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
FibroTest has been validated as a biomarker of fibrosis in patients with…
-
Noninvasive Testing for Nonalcoholic Steatohepatitis and Hepatic Fibrosis in Patients With Psoriasis Receiving Long-term Methotrexate Sodium Therapy.
…method is needed for the noninvasive monitoring of the development and progression…
-
Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C. Key publication
### Background The FibroTest and ActiTest are noninvasive biochemical markers of liver injury…
-
Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers. Review
The correct identification of patients at increased risk of non-alcoholic steatohepatitis…
-
Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients.
…advanced hepatic fibrosis or cirrhosis. ### Methods Subjects who had liver biopsy and…
-
Validation and comparison of indexes for fibrosis and cirrhosis prediction in chronic hepatitis C patients: proposal for a pragmatic approach classification without liver biopsies.
Noninvasive indexes have been developed to predict fibrosis staging. The aim of…
-
FibroTest-FibroSURE: towards a universal biomarker of liver fibrosis?
Among the noninvasive alternatives to liver biopsy, several studies have demonstrated the…
-
Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
…Non-invasive methods for the diagnosis of liver fibrosis, such as transient…
-
Liver fibrosis in adults with Fontan palliation: Do common screening studies predict disease severity?
-
Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.
…with 5-year follow-up. Noninvasive algorithms combining biological parameters (FibroMax^®^) were…
-
Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes. Key publication
…NASH grades and steatosis grades. ### Methods We prospectively analysed 272 patients with…
-
Hepatitis C virus viremia and low platelet count: a study in a hepatitis B & C endemic area in Taiwan.
…in individuals with HCV infection. ### Methods A large-scale survey, enrolling 11…
-
Independent prospective multicenter validation of biochemical markers (fibrotest-actitest) for the prediction of liver fibrosis and activity in patients with chronic hepatitis C: the fibropaca study. Key publication
…patients with chronic hepatitis C. ### Methods A total of 519 consecutive patients…
-
The Diagnostic Value of FibroTest and Hepascore as Non-Invasive Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC).
The aim of this study was to evaluate the diagnostic usefulness of…
-
Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis. Key publication
…would exclude non-evaluable participants METHODS: Biopsy was used as the reference…
-
Evaluation of FibroTest-ActiTest in children with chronic hepatitis C virus infection. Key publication
…virus (HCV) infection as a noninvasive alternative to liver biopsy (LB), but…
-
Noninvasive Markers of Improvement of Liver Steatosis Achieved by Weight Reduction in Patients with Nonalcoholic Fatty Liver Disease.
…lead to improvement of steatosis. ### Methods In a prospective observational study 86…
-
Concordance in a world without a gold standard: a new non-invasive methodology for improving accuracy of fibrosis markers.
…invasive endpoint and vice versa. ### Methods The proof of concept was taken…
-
Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference. Key publication
…ActiTest for inflammation activity grading. ### Methods We pre-included new NAFLD patients…
-
Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus.
Fibromax is a diagnostic tool composed of the combination of 4 non…
-
Screening studies of transient elastography and FibroTest in the general population.
-
Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease.
…Validated noninvasive tests (FibroMax: SteatoTest, NashTest and FibroTest) were used to assess…
-
Systematic review and meta-analysis of the diagnostic accuracy of fibrosis marker panels in patients with HIV/hepatitis C coinfection. Meta Analysis
### Background Accurately staging hepatitis C virus (HCV)-related fibrosis is crucial for…
-
Poynard T, Imbert-Bismut F, Ratziu V, Myers RP, Di Martino V, Thabut D, Moussalli J, Benhamou Y
-
Evolving practices of non-invasive markers of liver fibrosis in patients with chronic hepatitis C in France: time for new guidelines?
-
A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.
…UDCA) in patients with NASH. ### Methods We conducted a 12-month, randomized…
-
LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis. Key publication
…limited to patients with cirrhosis. ### Methods We performed a retrospective analysis in…
-
Longitudinal assessment of hepatitis C fibrosis progression by collagen and smooth muscle actin morphometry in comparison to serum markers.
…in fibrosis on paired biopsies. ### Methods The study cohort included 201 chronic…
-
Predicting significant fibrosis in hepatitis C patients in Luxembourg using serological markers.
…chronic hepatitis C. ### Materials And Methods Stored serum obtained from 186 patients…
-
Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.
…of the most commonly used noninvasive, blood-based biomarkers for liver fibrosis…
-
Severity of Fontan-Associated Liver Disease Correlates with Fontan Hemodynamics.
Fontan-palliated patients are at risk for the development of Fontan-associated…
-
Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests.
…seven non-invasive laboratory tests. ### Methods One hundred and three alcoholic patients…
-
Input of serum haptoglobin fucosylation profile in the diagnosis of hepatocellular carcinoma in patients with non-cirrhotic liver disease. Key publication
…Cancer-Risk-test (LCR1-test). ### Methods We retrospectively selected patients, 102 with…
-
Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis C.
…The secondary aim was to validate these accuracies in independent populations. ### Methods…
-
Evolution of biomarkers of liver fibrosis and liver insufficiency in hepatitis C virus-infected patients treated with pegylated interferon plus ribavirin and rituximab.
Therapeutic options in hepatitis C virus (HCV)-related vasculitis may target the…
-
Long-term prognostic value of the FibroTest in patients with non-alcoholic fatty liver disease, compared to chronic hepatitis C, B, and alcoholic liver disease. Key publication
### Background Although the FibroTest has been validated as a biomarker to determine…
-
Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
…biopsy or using non-invasive methods, might be different in chronic hepatitis…
-
Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication
Liver fibrosis is a common pathway leading to cirrhosis, which is the…
-
Noninvasive biomarkers FibroTest and ActiTest versus liver biopsy in chronic hepatitis C patients: the Middle East experience.
### Background The aim of this study was to compare noninvasive biomarkers, FibroTest…
-
Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population.
Retrospective studies suggest that coffee consumption may exert beneficial effects in patients…
-
Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
-
An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
Chronic hepatitis C remains a significant medical and economic burden in Canada…
-
Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).
…strategies in the general population. ### Methods We prospectively studied 7,463 consecutive…
-
Biomarkers for liver disease in urea cycle disorders.
…for liver fibrosis in UCDs. ### Methods We evaluated grey-scale ultrasonography, liver…
-
European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD) and European Association for the Study of Obesity (EASO) clinical practice recommendations for the management of non-alcoholic fatty liver disease: evaluation of their application in people with Type 2 diabetes.
…people with Type 2 diabetes. ### Methods A total of 179 people with…
-
Applicability and variability of liver stiffness measurements according to probe position.
…the region of liver biopsy. ### Methods The applicability for LSM was defined…
-
Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study. Key publication
…calcification in patients with T2D. ### Methods The lower limb arterial calcification score…
-
A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C.
…combining non-invasive fibrosis tests. ### Methods In all, 729 patients with CHC…
-
Finasteride and methadone use and risk of advanced hepatitis C related liver disease.
…hepatitis C virus (HCV) infection. ### Methods In a cross-sectional study in…
-
Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Key publication
…significant fibrosis (including early stages). ### Methods We assessed liver-biopsy patients with…
-
Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials.
…three randomized sham controlled studies. ### Methods The FibroMax test was performed in…
-
Intra-laboratory analytical variability of biochemical markers of fibrosis (Fibrotest) and activity (Actitest) and reference ranges in healthy blood donors.
Combinations of tests comprising alpha2-macroglobulin, haptoglobin, apolipoprotein Al, gamma-glutamyltransferase, total…
-
Optimization and robustness of blood tests for liver fibrosis and cirrhosis.
…evaluate their robustness. ### Design And Methods The derivation population included 1056 HCV…
-
Diagnostic value of serum protein profiling by SELDI-TOF ProteinChip compared with a biochemical marker, FibroTest, for the diagnosis of advanced fibrosis in patients with chronic hepatitis C.
…prediction of advanced liver fibrosis. ### Methods Sera from 191 consecutive patients with…
-
Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts. Key publication
…calcification in patients with T2D. ### Methods A total of 157 and 460…
-
Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
As of 2016, there is no evidence-based pathway to stratify the…
-
Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.
…of fibrosis presumed by FibroTest™. ### Methods In a prospective cohort, the main…
-
Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication
…NT) in patients with NAFLD. ### Methods 160 patients with NAFLD were prospectively…
-
Screening for liver disease using non-invasive biomarkers (FibroTest, SteatoTest and NashTest) in patients with hyperlipidaemia.
…large population of hyperlipidaemic patients. ### Methods A consecutive cohort of hyperlipidaemic patients…
-
Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.
…chronic liver disease. ### Patients And Methods Consecutive patients with chronic liver disease…
-
EASL clinical practical guidelines: management of alcoholic liver disease.
-
Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.
As an alternative to liver biopsy, an index of five biochemical markers…
-
Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.
### Background Liver biopsy is the reference standard for assessing liver fibrosis and…
-
FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC³ program.
…SVR) in previously treated patients. ### Methods Of 2312 patients enrolled, 1459 had…
-
Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy.
…thrombocytopenia not associated with cirrhosis. ### Methods The study included 1268 patients with…
-
Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
Traditionally a disease of hepatologists, nonalcoholic fatty liver disease (NAFLD) has recently…
-
Toward non-invasive assessment strategies in autoimmune hepatitis.
In this article, we comment on the article by Peta _et al…
-
Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).
…primary liver cancer, variceal bleeding, or decompensation (ascites, encephalopathy, or jaundice). ### Methods…
-
Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
…HIV/HCV co-infected patients. ### Methods Transient elastography (TE) and six blood…
-
Cost effectiveness of fibrosis assessment prior to treatment for chronic hepatitis C patients.
…a screening alternative to biopsy. ### Methods We assessed the cost-effectiveness of…
-
Intra-individual fasting versus postprandial variation of biochemical markers of liver fibrosis (FibroTest) and activity (ActiTest).
BACKGROUND: Biochemical marker combinations, including alpha2-macroglobulin, haptoglobin, apolipoprotein A1, gamma-glutamyl…
-
Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.
…compared with CHC and NAFLD. ### Methods Patients with CHB (N=110), CHC…
-
Role of genotype G hepatitis B virus mixed infection on the progression of hepatic fibrosis in HIV positive patients over 5 years of follow-up.
…to assess, using non-invasive methods, liver disease progression in HIV-HBV…
-
Twenty-year protocol liver biopsies: Invasive but useful for the management of liver recipients.
…This study aimed to examine the usefulness of 20-year LBs. ### Methods…
-
Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin.
Liver fibrosis and activity indexes were validated in patients infected by hepatitis…
-
Usefulness of acoustic radiation force impulse and fibrotest in liver fibrosis assessment after liver transplant.
### Unlabelled Background and rationale. Acoustic radiation force impulse (ARFI) is a non…
-
A prospective assessment of an 'a la carte' regimen of PEG-interferon alpha2b and ribavirin combination in patients with chronic hepatitis C using biochemical markers.
In therapy with standard interferon and ribavirin, five independent risk factors (RF…
-
The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease. Key publication
…with chronic alcoholic liver disease. ### Methods Biomarkers were assessed in patients with…
-
Evaluation and improvement of a reliable diagnosis of cirrhosis by blood tests.
…by two usual blood tests. ### Methods Reliable diagnosis was mainly evaluated by…
-
Prospective evaluation of FibroTest®, FibroMeter®, and HepaScore® for staging liver fibrosis in chronic hepatitis B: comparison with hepatitis C.
…B compared to hepatitis C. ### Methods 510 patients mono-infected with hepatitis…
-
Hepatoprotective Effect of Antrodia cinnamomea Mycelium in Patients with Nonalcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial.
### Objective Nonalcoholic steatohepatitis (NASH) has become a prominent liver disease in contemporary…
-
Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication
-
Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19. Key publication
In patients with non-alcoholic fatty liver disease (NAFLD) with or without…
-
Comparison of non-invasive fibrosis markers and classical liver biopsy in chronic hepatitis C.
The aim of this study was to compare the results of nine…
-
Performance of serum apolipoprotein-A1 as a sentinel of Covid-19. Key publication
…performance for the Covid-19. ### Methods We compared the daily mean serum…
-
Personalized management of cirrhosis by non-invasive tests of liver fibrosis. Review
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
-
Improved inflammatory activity with peginterferon alfa-2b maintenance therapy in non-cirrhotic prior non-responders: a randomized study.
…previously failed hepatitis C retreatment. ### Methods Patients with F2/F3 MFS who…
-
Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies. Meta Analysis
…HBV and HCV infection trials. ### Methods Studies were included if there were…
-
Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…1969 to January 2010). ### Review Methods Study quality was assessed using the…
-
Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.
…hepatitis C virus (HCV) infection. ### Methods We conducted a cross-sectional study…
-
Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
…FT), in patients with NAFLD. ### Methods 170 patients with suspected NAFLD were…
-
Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients.
### Unlabelled Nonalcoholic fatty liver disease (NAFLD) is highly prevalent and being overweight…
-
PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.
### Context Recently, it has been shown that an allele in the adiponutrin…
-
Role of leisure-time physical activity in nonalcoholic fatty liver disease: a population-based study.
…adiponectin, and resistin; and the noninvasive biomarker SteatoTest and anthropometric evaluations. A…
-
Clinical and genetic definition of serum bilirubin levels for the diagnosis of Gilbert syndrome and hypobilirubinemia.
-
Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection
These are the first World Health Organization (WHO) guidelines for the prevention…
-
Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C.
SUMMARY: BACKGROUND: Recent studies strongly suggest that due to the limitations and…
-
EASL Clinical Practice Guidelines: management of hepatitis C virus infection.
-
The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication
### Background Biopsy is the usual gold standard for liver steatosis assessment. The…
-
Guidelines for the Screening, Care and Treatment of Persons with Hepatitis C Infection Key publication
These are the first guidelines dealing with hepatitis C treatment produced by…
-
Prise en charge des personnes infectées par les virus de l’hépatite B ou de l’hépatite C — Rapport de recommandations 2014 Key publication
Mostrando la lista completa de resultados. La página se renderiza en el servidor y no está paginada.