Pubblicazioni scientifiche sui diagnostici non invasivi BioPredictive
Studi sottoposti a revisione paritaria che convalidano i diagnostici ematici BioPredictive per le malattie del fegato — dalle coorti di sviluppo pionieristiche alle meta-analisi a lungo termine.
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Risultati per
“Liver-related mortality”
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Role of Non-hepatic Medical Comorbidity and Functional Limitations in Predicting Mortality in Patients with HCV.
### Background Medical comorbidities and functional status limitations are determinants of mortality in…
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Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
…The leading causes of mortality were cancer (31%) and cardiovascular-related death…
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
### Background And Aim Mortality of alcohol-related liver disease (ArLD) is increasing…
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Management of the patient with SVR. Review
…liver complications, hepatocellular carcinoma and mortality. Additional benefits include reduced morbidity related…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.
…with liver fibrosis had more cardiovascular events and higher mortality (Hazard ratio…
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Editorial: FibroTest to predict liver-related mortality in NAFLD. Should this change the diagnostic algorithm in NAFLD?
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Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.
…Four cases of primary liver cancer occurred in SVR [4.6% (0…
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Long-term prognostic value of the FibroTest in patients with non-alcoholic fatty liver disease, compared to chronic hepatitis C, B, and alcoholic liver disease.
…Ten year survival (95% CI) without liver-related death in patients with…
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An Invisible Early Steatosis Phenotype Defined for a Large Population-Based Cohort.
**Background:** The current definition of metabolic dysfunction-associated steatotic liver disease (MASLD…
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HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.
…Liver-related and non-liver-related outcomes were documented. Overall 213 episodes…
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Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.
### Background Non-invasive liver fibrosis scores have been proposed as alternatives to…
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Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
…Validated non-invasive tests for liver fibrosis consistently detected otherwise unrecognised liver…
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EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease.
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Noninvasive diagnosis in alcohol-related liver disease.
### Background Alcohol-related liver disease (ALD) represents a major cause of death…
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First-line assessment of patients with chronic liver disease with non-invasive techniques and without recourse to liver biopsy.
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Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers. Review
…of non-liver- and liver-related morbidity and mortality. More expensive tests…
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Cost effectiveness of fibrosis assessment prior to treatment for chronic hepatitis C patients.
### Background And Aims Chronic hepatitis C (HCV) is a liver disease affecting…
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Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease.
…liver disease (NAFLD) is independently linked to cardiometabolic morbidity and mortality. Low…
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Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).
…as prognostic markers of liver related mortality in patients with chronic hepatitis…
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Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
Even though alcohol-related liver disease (ALD) is a major cause of…
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Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: the fibrovic study--ANRS HC02.
### Background/Aims To compare non-invasive biological liver fibrosis scores, as alternatives…
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Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…development of alcohol-related liver disease (ALD). Liver biopsy may be used…
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Screening for liver disease using non-invasive biomarkers (FibroTest, SteatoTest and NashTest) in patients with hyperlipidaemia.
### Background Mortality related to complications of cirrhosis is increasing in patients with…
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Non-invasive diagnosis and follow-up of portal hypertension.
…liver-related morbidity and mortality. In patients at risk of chronic liver…
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Guidelines for the Screening, Care and Treatment of Persons with Hepatitis C Infection Key publication
These are the first guidelines dealing with hepatitis C treatment produced by…
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Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection
…most advanced liver disease and at greatest risk of mortality; and recommend…
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Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
…Progressive liver injury is a concern in HIV-infected children exposed to…
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Assessment of liver fibrosis: noninvasive means.
Liver biopsy, owing to its limitations and risks, is an imperfect gold…
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis. Review
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
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Noninvasive evaluation of NAFLD. Review
…developing complications of end-stage liver disease. Although it lacks sensitivity, ultrasonography…
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Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection. Review
…a major cause of liver morbidity and mortality worldwide. While a proportion…
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A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C. Key publication
### Background FibroTest, a noninvasive method of measuring biomarkers of liver fibrosis, is…
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Non-invasive assessment of liver fibrosis: are we ready?
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FibroTest (FT) has similar accuracy for cirrhosis in 'intention-to-diagnose' which is superior to transient elastography (TE) in chronic hepatitis B.
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Non-invasive diagnosis of hepatitis B virus-related cirrhosis. Review
…Liver biopsy is the reference standard for assessment of liver fibrosis. However…
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Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.
### Aim The objective of this study was to evaluate liver fibrosis using…
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Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease.
…cause of cirrhosis and liver-related mortality, but we lack serum markers…
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Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication Review
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Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Key publication
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Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts.
…hand and non-alcoholic fatty liver disease (NAFLD) on the other hand…
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Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.
…of liver disease severity. ### Objective To compare the awareness of liver disease…
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Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
### Background Liver disease is the third leading cause of mortality in patients…
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Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
…In patients with chronic liver diseases, level of fibrosis predicts liver-related…
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Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV co-infected patients with chronic hepatitis.
…Serum levels of 25(OH)D3 were also significantly correlated with liver…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
…At 5 years, 25 patients were dead (13 liver-related deaths) and…
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Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
…Eighty-five patients died, including 42 deaths related to liver complications. The…
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Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.
…95% of patients received prednisolone; and the 2-year mortality was 63…
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Liver fibrosis regression and progression during controlled hepatitis B virus infection among HIV-HBV patients treated with tenofovir disoproxil fumarate in France: a prospective cohort study.
…Incidence of severe liver-related events was low (_n _= 4, rate = 0…
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The new paradigm of hepatitis C therapy: integration of oral therapies into best practices. Review
…Assessments of histologic damage typically are performed using liver biopsy, yet noninvasive…
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Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.
…Incident liver-related events occurred in profiles other than A (B, n…
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Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).
…and TE were predictive of liver complications (n=37; AUROC=0.83…
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Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study.
…Beyond its utility in assessing liver fibrosis, the FibroTest® could be a…
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[Prognosis assessment of alcoholic liver disease: how and why?]. Review
Alcoholic liver disease (ALD) causes more than 5000 deaths per year in…
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Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.
Transient elastography (TE) is a noninvasive technique to evaluate liver fibrosis. We…
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Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
…of liver morbidity and mortality in non-alcoholic fatty liver disease (NAFLD…
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Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers.
…Transient elastography has been evaluated for noninvasive staging of liver fibrosis in…
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Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication Review
…Several methodological issues are related to the classical methodology using biopsy, as…
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Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.
### Background Liver biopsy is considered as the gold standard for assessing nonalcoholic…
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Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).
### Background FibroTest and elastography have been validated as biomarkers of liver fibrosis…
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Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
### Background Liver fibrosis in human immunodeficiency virus (HIV)-infected individuals is mostly…
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Noninvasive Markers of Improvement of Liver Steatosis Achieved by Weight Reduction in Patients with Nonalcoholic Fatty Liver Disease.
### Unlabelled Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance…
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Real-world efficacy and safety of ombitasvir, paritaprevir/r+dasabuvir+ribavirin in genotype 1b patients with hepatitis C virus cirrhosis.
…most of them liver decompensation (1.9%), related to hepatic dysfunction, and…
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EASL Clinical Practice Guidelines: management of hepatitis C virus infection.
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Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods. Review
### Background Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of…
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American Association for the Study of the Liver
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Impact of hepatitis C and liver fibrosis on antiretroviral plasma drug concentrations in HIV-HCV co-infected patients: the HEPADOSE study.
…infected patients with liver disease documented by liver biopsy, matched with HIV…
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Performance of 11 biomarkers for liver fibrosis assessment in HIV/HBV co-infected patients.
…The Kappa index was used to study overall agreement with liver biopsy…
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Validation of liver fibrosis biomarker (FibroTest) for assessing liver fibrosis progression: proof of concept and first application in a large population.
### Background & Aims Time-dependent statistics have been used to assess liver fibrosis…
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PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.
…not selected for liver abnormalities, liver fibrosis was related to the rs738409…
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication Meta Analysis
…value of liver complications or death related to liver disease. A total…
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Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
…relevant morbidity and mortality caused by CF-related liver-disease. While transient…
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Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
…Routine assessment of liver fibrosis was requested by the surveyed physicians mostly…
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Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis.
### Background No prospective diagnostic studies have directly compared widespread non-invasive liver…
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Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. Review
…stage of alcohol-related liver injury is histology, liver biopsy is not…
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A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.
…a prevalent liver disease associated with increased morbidity and mortality. Ursodeoxycholic acid…
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Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.
### Introduction Hepatitis C virus (HCV) is the major cause of chronic liver…
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Non-invasive markers for hepatic fibrosis. Review
…The rate of adoption of non-invasive diagnostic tests for liver fibrosis…
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Performance of serum apolipoprotein-A1 as a sentinel of Covid-19. Key publication
…followed for a risk of liver fibrosis risk in the USA (212…
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Liver fibrosis markers in alcoholic liver disease. Review
Alcohol is one of the main factors of liver damage. The evaluation…
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Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.
…Eight patients reported nine serious adverse events; none was considered related to…
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Biochemical markers of liver fibrosis: a comparison with historical features in patients with chronic hepatitis C.
### Objectives Liver fibrosis in chronic hepatitis C is related to sex, age…
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
In Egypt, as elsewhere, liver biopsy (LB) remains the gold standard to…
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Liver biopsy: the best standard...when everything else fails.
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Prevalence of liver cirrhosis in individuals with hepatitis B virus infection in sub-Saharan Africa: Systematic review and meta-analysis. Meta Analysis
…Since HBV-related cirrhosis is an indication for immediate antiviral therapy and…
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Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.
As an alternative to liver biopsy, an index of five biochemical markers…
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Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.
…The optimal cut-off values of liver stiffness (LS) for predicting METAVIR…
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Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients.
…Further studies are needed to guide strategies for surveillance of liver disease…
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Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
Traditionally a disease of hepatologists, nonalcoholic fatty liver disease (NAFLD) has recently…
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Severity of Fontan-Associated Liver Disease Correlates with Fontan Hemodynamics.
…Severe liver cirrhosis was detectable in 20 patients (17.1%). Median liver…
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EASL clinical practice guidelines: Management of chronic hepatitis B virus infection.
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Role of genotype G hepatitis B virus mixed infection on the progression of hepatic fibrosis in HIV positive patients over 5 years of follow-up.
…The dynamic of liver disease in co-infected patients is important to…
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Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.
…these findings in women and in people with other chronic liver diseases.
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Performances of Elasto-FibroTest(®), a combination between FibroTest(®) and liver stiffness measurements for assessing the stage of liver fibrosis in patients with chronic hepatitis C.
### Background FibroTest(®) (FT), and liver stiffness measurement (LSM) are the most validated…
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Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19.
In patients with non-alcoholic fatty liver disease (NAFLD) with or without…
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Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
### Objective Chronic viral hepatitis B and C cause liver fibrosis, leading to…
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Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?
…Among the 2,169 patients who underwent liver biopsy, bridging fibrosis (F2…
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Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
Changes in the liver and bile ducts observed in patients diagnosed with…
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Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.
…Evaluation of liver fat was performed using four noninvasive methods: the SteatoTest…
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EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
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Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.
…In CHB, IR was related to host and not viral factors. CHB…
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An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
Chronic hepatitis C remains a significant medical and economic burden in Canada…
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The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease.
…The use of AshTest may reduce the need for liver biopsy, and…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV. Review
Patients with HIV have a proclivity to develop liver fibrosis, especially when…
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Noninvasive assessment of portal hypertension in patients with cirrhosis. Review
…Certain methods evaluate elements related to the pathogenesis of portal hypertension through…
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Factors to improve the management of hepatitis C in drug users: an observational study in an addiction centre.
Barriers to management of HCV in injection drug users are related to…
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Biomarkers as a first-line estimate of injury in chronic liver diseases: time for a moratorium on liver biopsy?
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Screening for liver fibrosis by using a noninvasive biomarker in patients with diabetes.
### Background & Aims Patients with diabetes are at risk for nonalcoholic fatty liver…
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Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
### Introduction Identifying liver fibrosis is important to evaluate the severity of liver…
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Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies. Meta Analysis
### Background Liver biopsy and virological end points are standard references for assessing…
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Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis. Review
### Background Liver fibrosis is a sign of advanced liver disease and is…
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Biomarkers of liver fibrosis. Review
Liver biopsy, due to its limitations and risks, is an imperfect gold…
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An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load. Key publication
…The main endpoint was the absence of liver-related complications, transplantation or…
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An evaluation of the potential cost-effectiveness of non-invasive testing strategies in the diagnosis of significant liver fibrosis.
…In comparison with liver biopsy alone, there was a cost savings of…
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European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD) and European Association for the Study of Obesity (EASO) clinical practice recommendations for the management of non-alcoholic fatty liver disease: evaluation of their application in people with Type 2 diabetes.
…Liver fat content (assessed using proton magnetic resonance spectroscopy), fatty liver index…
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Comparison of liver stiffness, fibrotest and liver biopsy for assessment of liver fibrosis in kidney-transplant patients with chronic viral hepatitis.
To assess the accuracy of the noninvasive tools, fibrotest (FT) and liver…
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The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B.
…of the liver biopsy (up to 0.94 for liver biopsies >or…
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Retracted: Executive functions in chronic hepatitis C virus infected elderly patients.
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A prospective assessment of the inter-laboratory variability of biochemical markers of fibrosis (FibroTest) and activity (ActiTest) in patients with chronic liver disease.
…Biochemical markers for liver fibrosis (FibroTest) and necroinflammatory features (ActiTest) are an…
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Systematic review and meta-analysis of the diagnostic accuracy of fibrosis marker panels in patients with HIV/hepatitis C coinfection. Meta Analysis
### Background Accurately staging hepatitis C virus (HCV)-related fibrosis is crucial for…
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Usefulness of acoustic radiation force impulse and fibrotest in liver fibrosis assessment after liver transplant.
…This study aimed to assess the accuracy of ARFI in discriminating liver…
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The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
…in order to avoid the liver biopsy currently used for selection of…
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Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review. Review
…the infection, have developed advanced liver disease. Until recently, in order to…
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A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation. Review
…Although, liver biopsy is still considered as gold standard to identify liver…
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FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis. Meta Analysis
### Objectives Extent of liver fibrosis is one of the most important factors…
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Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.
…Histological features were assessed invasively by liver biopsy and noninvasively using FibroTest…
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The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
### Background Nonalcoholic fatty liver disease (NAFLD) is common in bariatric surgery candidates…
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The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
…Liver biopsy samples, NIT results, and PROs (Short Form-36, Chronic Liver…
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Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study.
…Investigations included assessment of abdominal ultrasonography, liver biopsy, calculation of body mass…
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Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials.
…liver injury. ### Conclusion A number of non-invasive markers of liver damage…
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Non-invasive diagnosis of large oesophageal varices with FibroTest in patients with cirrhosis: a preliminary retrospective study.
…As portal hypertension is related to liver fibrosis, this study aimed to…
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Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population.
…Fatty liver was diagnosed with abdominal ultrasound and liver steatosis was quantified…
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Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics.
…The best marker of liver fibrosis in alcoholic patients seems to be…
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Prognostic value of liver fibrosis biomarkers: a meta-analysis.
…For the prediction of survival without liver-related death, the areas under…
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Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.
…from liver biopsies. ### Results Data from 182 patients with baseline liver biopsy…
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Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
…evaluated for the assessment of liver fibrosis predominantly in patients with viral…
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Spleen stiffness measurement by transient elastography to diagnose portal hypertension in children.
…Fibrotest was determined in 37 children, 45 children had an additional liver…
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Applicability and variability of liver stiffness measurements according to probe position.
### Aim To investigate the liver stiffness measurement (LSM) applicability and variability with…
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Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
…The Enhanced Liver Fibrosis (ELF) test consists of an algorithm of three…
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HCV-GenoFibrotest: a combination of viral, liver and genomic (IL28b, ITPA, UGT1A1) biomarkers for predicting treatment response in patients with chronic hepatitis C.
### Background And Aim Three gene polymorphisms, interferon-lambda-3 (IL28B), inosinetriphosphatase (ITPA…
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Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy.
### Background The efficiency of transient elastography for the assessment of liver fibrosis…
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Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
…Existing guidelines do not advocate screening for liver related complications amongst persons…
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Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data. Meta Analysis
### Background Liver biopsy is considered as the gold standard for assessing non…
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Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.
### Background Progression of recurrent hepatitis C is accelerated in liver transplant recipients…
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Efficacy and safety of tenofovir disoproxil fumarate in Asian-Americans with chronic hepatitis B in community settings.
…Secondary endpoints were safety and tolerability, serologic and biochemical responses, liver fibrosis…
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Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
…risk for intestinal failure-associated liver disease (IFALD). The aim of the…
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Relationship between the Fibrotest and portal hypertension in patients with liver disease.
…of PHT in patients with liver disease, and to determine if the…
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Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali.
…to severe liver fibrosis and 60% have detectable aflatoxin-related TP53 R249S…
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Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.
…liver disease (NAFLD). NAFLD severity and its implication in OSA-related endothelial…
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The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
…Steatosis was demonstrated in all 5 patients who received liver biopsies during…
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Validation of the Performance of A1HPV6, a Triage Blood Test for the Early Diagnosis and Prognosis of SARS-CoV-2 Infection.
### Background And Aims Apolipoprotein A1 (A1) and haptoglobin (HP) serum levels are…
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Progression of liver fibrosis among injection drug users with chronic hepatitis C.
…Baseline liver biopsies were obtained (1996-1998) on a random sample of…
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Diagnostic value of serum protein profiling by SELDI-TOF ProteinChip compared with a biochemical marker, FibroTest, for the diagnosis of advanced fibrosis in patients with chronic hepatitis C.
### Background FibroTest has been validated for the diagnosis of liver fibrosis in…
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Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.
### Background Many blood tests have been proposed as alternatives to liver biopsy…
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A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C.
### Objectives Precise evaluation of the level of liver fibrosis is recommended in…
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Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication
…The impact of treatment with ADV vs placebo was assessed on liver…
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Ministère des Affaires Sociales et de la Santé Key publication
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Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.
…Significant liver-related events (SLRE) and liver-related deaths were recorded during…
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Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups.
### Background Our aim was to assess the natural history of liver fibrosis…
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Twenty-year protocol liver biopsies: Invasive but useful for the management of liver recipients.
### Background & Aims Most liver transplant centres have discontinued the practice of protocol…
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Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
### Background Liver fibrosis, now assessed by liver biopsy or using non-invasive…
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Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests.
### Background Systematic screening for liver fibrosis in heavy-drinking patients is a…
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
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Improved inflammatory activity with peginterferon alfa-2b maintenance therapy in non-cirrhotic prior non-responders: a randomized study.
…Blinded liver biopsies obtained before retreatment and after maintenance therapy were evaluated…
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The non-invasive assessment of hepatic fibrosis. Review
…Liver fibrosis, as the last stage of numerous chronic liver diseases, is…
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Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin.
…Three hundred fifty-two patients who had had 2 interpretable liver biopsies…
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LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis. Key publication
…in the prediction of primary liver cancer in patients without cirrhosis. ### Aim…
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Meta-analyses of FibroTest diagnostic value in chronic liver disease. Meta Analysis
### Background FibroTest (FT) is a biomarker of liver fibrosis initially validated in…
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Intra-laboratory analytical variability of biochemical markers of fibrosis (Fibrotest) and activity (Actitest) and reference ranges in healthy blood donors.
…being developed as alternatives to liver biopsy in patients with chronic hepatitis…
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The diagnostic performance of a simplified blood test (SteatoTest-2) for the prediction of liver steatosis. Key publication
### Background Serum biomarkers of steatosis such as the SteatoTest are recommended for…
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Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication
Liver fibrosis is a common pathway leading to cirrhosis, which is the…
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Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C.
### Background The FibroTest and ActiTest are noninvasive biochemical markers of liver injury…
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Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference.
…enrolled 103 patients for whom liver biopsy, hepatic elastography results, and laboratory…
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Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
### Background Liver biopsy is considered as the gold standard for assessing non…
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B. Meta Analysis
### Background Blood tests and transient elastography (TE), proposed as alternatives to biopsy…
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The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…However, liver biopsy is not replaceable, especially to diagnose ≥F2 and in…
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Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication
### Background Liver biopsy is considered the gold standard for assessing histologic lesions…
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The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication
### Background Biopsy is the usual gold standard for liver steatosis assessment. The…
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[Biomarkers for liver fibrosis: advances, advantages and disadvantages]. Review
Liver cirrhosis in Mexico is one of the most important causes of…
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