Pubblicazioni scientifiche sui diagnostici non invasivi BioPredictive
Studi sottoposti a revisione paritaria che convalidano i diagnostici ematici BioPredictive per le malattie del fegato — dalle coorti di sviluppo pionieristiche alle meta-analisi a lungo termine.
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Risultati per
“AST-to-platelet ratio index”
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Comparison of non-invasive fibrosis markers and classical liver biopsy in chronic hepatitis C.
…FIB4, AST/platelet ratio index (APRI), age-platelet (AP) index, Göteborg University…
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Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.
…the platelet count, age-platelet index, aspartate aminotransferase-platelet ratio index (APRI…
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Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores.
…methods (AST/ALT ratio (AAR), APRI, prothrombin index (PI), platelet count (PC…
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Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.
…FibroTest®, aspartate aminotransferase-to-platelet ratio index(APRI), aspartate aminotransferase and alanine…
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Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection. Review
…Due to the complex natural history of HBV infection, patients require an…
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Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.
…of Fibrotest, Forns' index and AST-to-platelet ratio (APRI) have been…
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Performance of noninvasive markers for liver fibrosis is reduced in chronic hepatitis C with normal transaminases.
…for AST-to-platelet ratio, Forns' index, AST-to-ALT ratio (AAR…
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The non-invasive assessment of hepatic fibrosis. Review
…The liver biopsy with the histopathological examination is considered to be the…
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Personalized management of cirrhosis by non-invasive tests of liver fibrosis. Review
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
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The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B.
…index was more precise than the AST-to-platelet ratio index and…
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Non-invasive biomarkers of liver fibrosis in haemophilia patients with hepatitis C: can you avoid liver biopsy?
…FT, AST-to-platelet ratio index (APRI), Forns index, age-platelet index…
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Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.
…FS, Fibrotest, FIB-4, aspartate aminotransferase to platelet ratio index (APRI), and…
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Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease. Key publication
…The primary aim was to validate ELF in detection of advanced fibrosis…
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Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis. Review
…Transient elastography also appears to be an excellent tool for early detection…
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Usefulness of acoustic radiation force impulse and fibrotest in liver fibrosis assessment after liver transplant.
…This study aimed to assess the accuracy of ARFI in discriminating liver…
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Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
…Cut-offs were determined by Youden Index or 90% predictive values. ### Results…
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Is it possible to predict HCV-related liver cirrhosis non-invasively through routine laboratory parameters? Review
…In managing subjects with HCV chronic infection, it is crucial to perform…
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Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B.
…AST-to-Platelet ratio (APRI), Fornso index, AST-to-ALT Ratio, Goteborg…
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Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. Review
…to first tier screening of patients at risk, in order to diagnose…
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Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
…M probe; aspartate aminotransferase to platelet ratio index (APRI) and FibroTest (FT…
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A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation. Review
…Different invasive and non invasive methods are applied to diagnose the disease…
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Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
…SteatoTest, Forns index, aspartate aminotransferase to platelet ratio index, ultrasound, and Fibroscan…
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The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…APRI, Forns'index, Lok index, AST-to-ALT ratio, Fib-4, platelets…
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Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
…for FibroTest and AST to platelet ratio index. Histologic steatosis significantly correlated…
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Non-invasive markers for hepatic fibrosis. Review
…Current non-invasive methods range from serum biomarker assays to advanced imaging…
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Improving estimation of liver fibrosis using combination and newer noninvasive biomarker scoring systems in hepatitis C-infected haemophilia patients.
…FT, AST-to-platelet ratio index (APRI), Forns index, hyaluronic acid and…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV. Review
Patients with HIV have a proclivity to develop liver fibrosis, especially when…
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Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.
…Hepascore, Aspartate Transaminase (AST) to platelet ratio index [APRI], Forns score, FibroTest…
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SAFE biopsy: a validated method for large-scale staging of liver fibrosis in chronic hepatitis C.
…by combining the AST-to-platelet ratio index and Fibrotest-Fibrosure, thereby…
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Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers. Review
…4 index are both cost-effective and highly sensitive tools to exclude…
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Variability in definitions of transaminase upper limit of the normal impacts the APRI performance as a biomarker of fibrosis in patients with chronic hepatitis C: "APRI c'est fini ?".
### Background The aspartate aminotransferase platelet ratio index (APRI) is a validated, non…
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Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
…acid (HA), aspartate aminotransferase platelet ratio index (APRI), FibroTest, and Fib-4…
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The predictive value of Fibrotest vs. APRI for the diagnosis of fibrosis in chronic hepatitis C.
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Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
…The aim of the present study was to evaluate dynamic changes of…
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Transient elastography and biomarkers for liver fibrosis assessment and follow-up of inactive hepatitis B carriers.
…TE, Fibrotest and aspartate to platelet ratio index (APRI) the same day…
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FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest.
…The FIB-4 index was strongly correlated to the FibroTest results for…
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Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.
…Fibrotest, the Forn's index, age-platelet ratio index, SHASTA, FIB-4…
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Prognostic value of liver fibrosis biomarkers: a meta-analysis.
…as FibroTest, aspartate transaminase-platelet ratio index (APRI), FIB-4, and liver…
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Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.
Aim To assess concordance of eight frequently used serology-based scoring indices…
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Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.
…No patients discontinued treatment due to adverse events. Eight patients reported nine…
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Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
…aim of this study was to determine the accuracy of certain biomarkers…
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Noninvasive Assessment of Liver Fibrosis. Key publication Review
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Validation and comparison of indexes for fibrosis and cirrhosis prediction in chronic hepatitis C patients: proposal for a pragmatic approach classification without liver biopsies.
…FibroTest (FT), aspartate aminotransferase to platelet ratio index (APRI) and Forns score…
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Comparison of elastography, serum marker scores, and histology for the assessment of liver fibrosis in hepatitis B virus (HBV)-infected patients in Burkina Faso.
…for the aspartate transaminase to platelet ratio index (APRI), Fib-4, Fibrotest…
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Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.
…liver biopsy and aspartate aminotransferase-to-platelet ratio (APRI), fibrosis index-4…
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Non-invasive Investigations for the Diagnosis of Fontan-Associated Liver Disease in Pediatric and Adult Fontan Patients.
…cell and platelet counts were significantly decreased in comparison to the pediatric…
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness. Review
…suggested that the AST-to-platelet ratio index or FIB-4 test…
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External validation of FibroIndex.
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The predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and Forns index to noninvasively estimate fibrosis in hepatitis C and nonhepatitis C liver diseases.
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Progression of liver fibrosis among injection drug users with chronic hepatitis C.
…Predictive values of blood markers [FibroSURE, aspartate aminotransferase-to-platelet-ratio index…
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Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.
…Here, the authors aimed to assess the performance of the most commonly…
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Biomarkers for liver disease in urea cycle disorders.
### Background Urea cycle disorders (UCDs) are among the most common inborn errors…
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Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C. Review
…73.8, 94.9%, aspartate aminotransferase to platelet ratio index (APRI): 71…
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Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.
…FT) (Castera) or AST-to-Platelet Ratio Index (APRI) and FT (SAFE…
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Biological markers of liver fibrosis and activity as non-invasive alternatives to liver biopsy in patients with chronic hepatitis C and associated mixed cryoglobulinemia vasculitis.
…age-platelet, platelet, hyaluronic acid) as non-invasive alternatives to liver biopsy…
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Noninvasive evaluation of NAFLD. Review
A common clinical concern in patients with NAFLD is whether they have…
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Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection.
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[The prediction and validation of liver fibrosis by a noninvasive model and validation in patients with chronic hepatitis B].
…GGT and platelet is a simple and reliable index for predicting significant…
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Performance of 11 biomarkers for liver fibrosis assessment in HIV/HBV co-infected patients.
…The Kappa index was used to study overall agreement with liver biopsy…
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Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C.
…evaluated for AST to platelets ratio (APRI), Forns' index and Fibrotest at…
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Liver stiffness measurement in children using FibroScan: feasibility study and comparison with Fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy.
…to compare FibroScan, Fibrotest, and aspartate transaminase to platelets ratio index (APRI…
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Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
As of 2016, there is no evidence-based pathway to stratify the…
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Hepatitis C virus viremia and low platelet count: a study in a hepatitis B & C endemic area in Taiwan.
…This study aimed to elucidate the association between virologic status and platelet…
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Validation of biochemical markers for the prediction of liver fibrosis and necroinflammatory activity in hemodialysis patients with chronic hepatitis C.
…biopsy and the AST-to-platelet ratio index (APRI) in determining hepatic…
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
…Non-invasive tests (NITs) are increasingly used to detect fibrosis, but their…
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Biomarkers of liver fibrosis. Review
…FT has higher accuracy than aspartate aminotransferase/platelets ratio index (APRI), the…
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FibroTest has better diagnostic and prognostic values than the aspartate aminotransferase-to-platelet ratio index in patients with chronic hepatitis C.
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Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
### Introduction Identifying liver fibrosis is important to evaluate the severity of liver…
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Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
…0.71 (aspartate aminotransferase-to-platelet ratio index), 0.80 and 0…
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Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: the fibrovic study--ANRS HC02.
…Fib-4, APRI and the Forn's index were only able to…
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Systematic review and meta-analysis of the diagnostic accuracy of fibrosis marker panels in patients with HIV/hepatitis C coinfection. Meta Analysis
…Our objective was to systematically review studies describing the accuracy of serum…
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An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
…Lower index scores at baseline that continue to decline likely reflect reduced…
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The effectiveness of noninvasive biomarkers to predict hepatitis B-related significant fibrosis and cirrhosis: a systematic review and meta-analysis of diagnostic test accuracy. Meta Analysis
Noninvasive biomarkers have been developed to predict hepatitis B virus (HBV)-related…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
…In multivariate analysis, FibroTest and liver stiffness had the highest hazard ratio…
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Predicting significant fibrosis in hepatitis C patients in Luxembourg using serological markers.
### Objective The aim of our study was to assess the diagnostic performance…
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Serum bile acid levels as a predictor for the severity of liver fibrosis in patients with chronic hepatitis C.
…acids, age, body mass index, serum AST, glucose and cholesterol levels suggested…
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Assessment of liver fibrosis: noninvasive means.
Liver biopsy, owing to its limitations and risks, is an imperfect gold…
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FIB-4: a simple, inexpensive and accurate marker of fibrosis in HCV-infected patients.
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Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.
…leading to special need of non-invasive validated methods to estimate liver…
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Optimized stepwise combination algorithms of non-invasive liver fibrosis scores including Hepascore in hepatitis C virus patients.
…AUCs of aspartate aminotransferase (AST) to Platelets Ratio Index (APRI) and Forns…
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Evaluating the accuracy and increasing the reliable diagnosis rate of blood tests for liver fibrosis in chronic hepatitis C.
…0.799, aspartate aminotransferase to platelet ratio index (APRI): 0.786 and…
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Comparison of liver fibrosis blood tests developed for HCV with new specific tests in HIV/HCV co-infection.
### Background & Aims We compared 5 non-specific and 2 specific blood tests…
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Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
…The aim of the study was to evaluate the selected parameters of…
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Discordance between liver biopsy and FibroTest in assessing liver fibrosis in chronic hepatitis B.
…Here, we aimed to identify predictors of discordance between FT and liver…
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Validation of Ten Noninvasive Diagnostic Models for Prediction of Liver Fibrosis in Patients with Chronic Hepatitis B.
…The aim of this study was to verify the diagnostic performance and…
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EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
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Combination of fibrosis tests: sequential or synchronous?
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Comparison of transient elastography (FibroScan), FibroTest, APRI and two algorithms combining these non-invasive tests for liver fibrosis staging in HIV/HCV coinfected patients: ANRS CO13 HEPAVIH and FIBROSTIC collaboration.
…FT), the aspartate aminotransferase-to-platelet ratio index (APRI) and two algorithms…
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Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication
Liver fibrosis is a common pathway leading to cirrhosis, which is the…
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Reproducibility of blood tests of liver fibrosis in clinical practice.
### Objectives To evaluate the inter-laboratory reproducibility of blood test for liver…
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Non-invasive diagnosis of hepatitis B virus-related cirrhosis. Review
…Twenty-three percent of patients with CHB progress naturally to liver cirrhosis…
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Liver fibrosis markers in alcoholic liver disease. Review
…Staging of liver fibrosis is essential to define prognosis and management of…
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Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
…0.96 to 1.00) and 0.88 (0.76 to 0…
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Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
…FibroTest, the aspartate aminotransferase to platelet ratio index, FIB-4), and analyzed…
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Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy.
…The study population was subdivided according to baseline FibroSURE test results into…
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Prospective noninvasive analysis of hepatic fibrosis in patients with Crohn's disease: correlation of transient elastography and laboratory-based markers.
…Established markers of fibrosis, namely, aspartate transaminase-to-platelet ratio index (APRI…
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Fibrotest or Fibroscan for evaluation of liver fibrosis in haemophilia patients infected with hepatitis C.
Non-invasive modalities to estimate fibrosis stage are desirable in hepatitis C…
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Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.
…We aimed to validate its diagnostic performances in comparison with liver stiffness…
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Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
…However, to date, diagnostic performances of Enhanced Liver Fibrosis (ELF) test, which…
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Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.
As an alternative to liver biopsy, an index of five biochemical markers…
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Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.
…The aim of this study was to prospectively evaluate the performance of…
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Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.
### Background/Aims According to guidelines, the histological diagnosis of severe alcoholic steatohepatitis…
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Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.
…and was superior to other noninvasive methods (APRI Index, FibroMax) for staging…
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Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
…mortality and cardiovascular risk. ### Aim To evaluate the prognostic value of non…
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Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
…METAVIR F stages, body mass index, and platelet count were also independently…
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Hepatitis B: are non-invasive markers of liver fibrosis reliable? Review
Liver biopsy, which was traditionally considered to be the gold standard for…
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Evaluation of liver stiffness measurement by fibroscan as compared to liver biopsy for assessment of hepatic fibrosis in children with chronic hepatitis C.
…Fibrotest, Actitest, AST-to-platelet ratio index, Forns index and hyaluronic acid…
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Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
In Egypt, as elsewhere, liver biopsy (LB) remains the gold standard to…
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Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.
…and the aspartate transaminase to platelets ratio index [APRI]); a liver biopsy…
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Prevalence of liver cirrhosis in individuals with hepatitis B virus infection in sub-Saharan Africa: Systematic review and meta-analysis. Meta Analysis
…and cancer surveillance, we aimed to estimate the prevalence of cirrhosis among…
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Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection
…These recommendations provide opportunities to save lives, improve clinical outcomes of persons…
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Noninvasive diagnosis in alcohol-related liver disease.
…Among the noninvasive surrogate markers and techniques used to detect liver fibrosis…
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Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.
…In this study, we aimed to design a new score in chronic…
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B. Meta Analysis
…of FibroTest, aspartate aminotransferase-platelet ratio index (APRI), FIB4 or TE, with…
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An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
…In addition, recommendations are made regarding approaches to reducing the burden of…
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Development and validation of a nomogram based on clinical factors and standard laboratory tests for prediction of clinically significant liver fibrosis in chronic hepatitis C virus infection.
…The aim of this study was to develop a nomogram, on the…
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FibroSURE as a noninvasive marker of liver fibrosis and inflammation in chronic hepatitis B.
…with AST levels has an excellent capacity to identify moderate to high…
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Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
…During the last decade, non-invasive tests have been developed to estimate…
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Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
…Hepatic stellate cell activation index was also higher in CHC than in…
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Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
…nonalcoholic fatty liver disease leading to cirrhosis. Existing guidelines do not advocate…
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Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review. Review
…Until recently, in order to assess its severity, it was necessary to…
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Changes of non-invasive markers and FibroScan values during HCV treatment.
…The aim of this prospective study was to evaluate changes in liver…
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Successful treatment with telaprevir-based regimens for chronic hepatitis C results in significant improvements to serum markers of liver fibrosis.
…We sought to quantify whether liver health improves following successful treatment with…
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Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
…The aim of this study was to compare the diagnostic performance of…
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Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication Review
…A scoring system has been updated to better compare the quality of…
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A novel panel of blood markers to assess the degree of liver fibrosis.
The objective was to develop new blood tests to characterize different fibrosis…
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Non-invasive diagnosis and follow-up of portal hypertension.
…20 kPa or platelet count ≤50 G/l). Platelet count and liver…
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Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasive.
…with the aspartate aminotransferase-to-platelet ratio index (APRI) or FibroScan, are…
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Liver fibrosis in adults with Fontan palliation: Do common screening studies predict disease severity?
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Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
…The aim of the study was to compare the diagnostic and prognostic…
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Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
…The impact of other risk factors, including prolonged exposure to combined antiretroviral…
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Independent prospective multicenter validation of biochemical markers (fibrotest-actitest) for the prediction of liver fibrosis and activity in patients with chronic hepatitis C: the fibropaca study. Key publication
…The aim of this study was to perform an external validation of…
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Guidelines for the Screening, Care and Treatment of Persons with Hepatitis C Infection Key publication
…the expansion of clinical services to patients with HCV infection, as they…
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The risk of multiplying diagnostic combinations in the absence of a perfect gold standard for a fibrosis test.
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Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Key publication
…We aimed, in our prospective study, to assess the predictive value of…
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Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts. Key publication
…The primary objective of the present study was to investigate whether the…
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Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
### Objectives To evaluate the diagnostic performance of seven non-invasive tests (NITs…
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Liver fibrosis regression and progression during controlled hepatitis B virus infection among HIV-HBV patients treated with tenofovir disoproxil fumarate in France: a prospective cohort study.
…The aim of this study was to evaluate the evolution of liver…
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Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference. Key publication
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Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
…The aim of this study was to determine the diagnostic utility of…
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Altered serum N-glycomics in chronic hepatitis B patients.
…Our present study aimed to evaluate the use of serum glycan markers…
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Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study. Key publication
…This study aimed to investigate whether the biomarkers of MASLD included in…
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Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.
The diagnostic utilities of ultrasonography (US), fatty liver index (FLI) and an…
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Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin.
…The aim was to validate their usefulness as surrogate markers of histologic…
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Implementing non-invasive markers for liver fibrosis in clinical practice.
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Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests.
…Aims To assess Fibroscan for non-invasive diagnosis of asymptomatic liver fibrosis…
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[Biomarkers for liver fibrosis: advances, advantages and disadvantages]. Review
Liver cirrhosis in Mexico is one of the most important causes of…
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Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.
### Background & Objectives One of the multiple factors contributing to virological response in…
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The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
### Aim To assess the diagnostic value of FibroTest to discriminate between insignificant…
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Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods. Review
…The articles cited were selected based on their relevancy to the objective…
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Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
…Although the increasing prevalence of NAFLD is frequently attributed to the epidemic…
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Transient elastography alone and in combination with FibroTest® for the diagnosis of hepatic fibrosis in alcoholic liver disease.
### Background & Aims The reliability of transient elastography (TE) to assess liver fibrosis…
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Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.
…The aim of the present study was to validate real-time elastography…
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FibroMAX: towards a new universal biomarker of liver disease? Review
…and a better benefit-to-risk ratio than biopsy of five combinations…
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Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.
…Hepascore®) to 0.83 (FIB-4) for cirrhosis. ### Conclusions Contrarily to blood…
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Biomarkers for the prediction of liver fibrosis in patients with chronic alcoholic liver disease.
### Background & Aims The aim of this study was to determine the diagnostic…
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Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus.
…The purpose of this study was to assess the performance of these…
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Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
…liver fibrosis and cirrhosis. ### Aim To determine the diagnostic accuracy of ARFI…
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The new paradigm of hepatitis C therapy: integration of oral therapies into best practices. Review
…In replacing interferon-based therapies, all-oral regimens are expected to be…
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The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
…Of those with baseline F3 disease, 16.7% experienced disease progression to…
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Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver.
### Background The only way to diagnose nodular regenerative hyperplasia (NRH) is liver…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
…The aim of this case-control study was to determine factors associated…
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Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes. Key publication
…steatohepatitis (NASH) and steatosis. ### Aims To validate externally the performances of a…
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Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
…Histology was classified according to METAVIR and the Ludwig's classification (F0…
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Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C. Key publication
…The aims of this study were to assess the quality of biopsy…
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Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference. Key publication
…We used nonbinary-ROC (NonBinAUROC) as the main endpoint to prevent spectrum…
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Intra-individual fasting versus postprandial variation of biochemical markers of liver fibrosis (FibroTest) and activity (ActiTest).
…Considering this premise, the primary aim of this study was to assess…
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Clinical and genetic definition of serum bilirubin levels for the diagnosis of Gilbert syndrome and hypobilirubinemia.
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Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
…The aim of the present study was to evaluate the prevalence of…
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Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication
The aim was to assess the utility of FibroTest-ActiTest (FT-AT…
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Real-world efficacy and safety of ombitasvir, paritaprevir/r+dasabuvir+ribavirin in genotype 1b patients with hepatitis C virus cirrhosis.
…liver decompensation (1.9%), related to hepatic dysfunction, and lower platelet count.
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FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy. Meta Analysis
…Due to the limitations of biopsy, noninvasive alternatives including FibroTest and FibroScan…
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EASL Clinical Practice Guidelines: management of hepatitis C virus infection.
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FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC³ program.
…The aim of the present study was to assess FibroTest (FT), a…
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The Diagnostic Value of FibroTest and Hepascore as Non-Invasive Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC).
The aim of this study was to evaluate the diagnostic usefulness of…
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Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
A serum biomarker (FibroTest; Biopredictive, Paris, France; FibroSure; LabCorp, Burlington, USA) and…
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
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Non-invasive assessment of liver fibrosis progression in hepatitis C patients retreated for 96 weeks with antiviral therapy: a randomized study.
…Blood tests could be useful to assess liver fibrosis changes in clinical…
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication Meta Analysis
…The primary aim of the present study was to update a previous…
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Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…Database (from 1995 to January 2010), Cumulative Index to Nursing and Allied…
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Prospective evaluation of FibroTest®, FibroMeter®, and HepaScore® for staging liver fibrosis in chronic hepatitis B: comparison with hepatitis C.
…The aim of this study was to describe the diagnostic performance of…
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