Publications scientifiques sur les diagnostics non invasifs BioPredictive
Études évaluées par les pairs validant les diagnostics sanguins BioPredictive pour les maladies du foie — des cohortes pionnières aux méta-analyses à long terme.
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“FibroTest”
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Relationship between the Fibrotest and portal hypertension in patients with liver disease.
…The same day, blood samples for Fibrotest were performed. ### Results A total…
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Performances of Elasto-FibroTest(®), a combination between FibroTest(®) and liver stiffness measurements for assessing the stage of liver fibrosis in patients with chronic hepatitis C.
### Background FibroTest(®) (FT), and liver stiffness measurement (LSM) are the most validated…
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Correlation between liver biopsy and fibrotest in the evaluation of hepatic fibrosis in patients with chronic hepatitis C.
### Aim To assess the diagnostic value of Fibrotest in comparison with liver…
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Comparison of Fibrotest and PGAA for the diagnosis of fibrosis stage in patients with alcoholic liver disease.
…The Fibrotest score was computed using the Biopredictive website. The overall diagnostic…
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Intra-laboratory analytical variability of biochemical markers of fibrosis (Fibrotest) and activity (Actitest) and reference ranges in healthy blood donors.
…The impact of parameter analytical variability on Fibrotest and Actitest results was…
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Cost effectiveness of fibrosis assessment prior to treatment for chronic hepatitis C patients.
…FibroTest only; FibroTest with liver biopsy for ambiguous results; FibroTest followed by…
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Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease. Key publication
…In multivariate analysis the most significant was FibroTest (P = 0.001), without…
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FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy. Meta Analysis
…Due to the limitations of biopsy, noninvasive alternatives including FibroTest and FibroScan…
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The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
…Transient elastography and FibroTest were performed, and patients with abnormal results were…
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Non-invasive diagnosis of large oesophageal varices with FibroTest in patients with cirrhosis: a preliminary retrospective study.
…assess the predictive value of FibroTest, a non-invasive marker of liver…
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Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). Key publication
…We applied 3M to FibroTest-T2D to demonstrate this reduction of uncertainty…
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Prognostic value of liver fibrosis biomarkers: a meta-analysis.
### Aims And Methods Several serum biomarkers such as FibroTest, aspartate transaminase-platelet…
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Optimal correlation between different instruments for Fibrotest-Actitest protein measurement in patients with chronic hepatitis C.
…We evaluated Fibrotest-Actitest results obtained with the two nephelemeters. ### Results Optimal…
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Validation of the FibroTest biochemical markers score in assessing liver fibrosis in hepatitis C patients.
…We investigated the predictive value of the proprietary FibroTest score to accurately…
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Biomarkers of liver injury for hepatitis clinical trials: a meta-analysis of longitudinal studies. Meta Analysis
…In a comparison of HCV patients with controls, the FibroTest pFPy was…
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The FibroTest value in discriminating between insignificant and significant fibrosis in chronic hepatitis C patients. The Romanian experience.
### Aim To assess the diagnostic value of FibroTest to discriminate between insignificant…
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Noninvasive Markers of Hepatic Fibrosis in Chronic Hepatitis B.
A serum biomarker (FibroTest; Biopredictive, Paris, France; FibroSure; LabCorp, Burlington, USA) and…
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Comparison of FibroTest-ActiTest with histopathology in demonstrating fibrosis and necroinflammatory activity in chronic hepatitis B and C.
### Aims FibroTest and ActiTest are noninvasive tests used in determining the level…
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Impact of quality control accepted inter-laboratory variations on calculated Fibrotest/Actitest scores for the non-invasive biochemical assessment of liver fibrosis.
…Inter-laboratory variations of the calculated Fibrotest score for staging and Actitest…
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Non-alcoholic fatty liver disease biomarkers estimate cardiovascular risk based on coronary artery calcium score in type 2 diabetes: a cross-sectional study with two independent cohorts. Key publication
…FibroMax® panels (i.e., SteatoTest®, FibroTest®, NashTest®, and ActiTest®) were determined from…
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Transient elastography alone and in combination with FibroTest® for the diagnosis of hepatic fibrosis in alcoholic liver disease.
…Patients underwent liver biopsy, TE, Fibrotest^®^ , PGAA, APRI, FIB-4 and FORNS…
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Relative performances of FibroTest, Fibroscan, and biopsy for the assessment of the stage of liver fibrosis in patients with chronic hepatitis C: a step toward the truth in the absence of a gold standard.
…Two widely used techniques, FibroTest®, and liver stiffness measurement (LSM) using Fibroscan…
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Biochemical and biophysical assessment of MTX-induced liver fibrosis in psoriasis patients: Fibrotest predicts the presence and Fibroscan predicts the absence of significant liver fibrosis.
…The Fibroscan and the Fibrotest are two novel, non-invasive methods that…
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Liver biopsy analysis has a low level of performance for diagnosis of intermediate stages of fibrosis.
…The performance of FibroTest was also lower for the diagnosis of F2…
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Long-term prognostic value of the FibroTest in patients with non-alcoholic fatty liver disease, compared to chronic hepatitis C, B, and alcoholic liver disease. Key publication
### Background Although the FibroTest has been validated as a biomarker to determine…
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FibroScan and FibroTest to assess liver fibrosis in HCV with normal aminotransferases.
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FibroTest and Fibroscan performances revisited in patients with chronic hepatitis C. Impact of the spectrum effect and the applicability rate.
### Background Two widely used biomarkers of fibrosis, FibroTest and liver stiffness measurement…
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Staging chronic hepatitis B into seven categories, defining inactive carriers and assessing treatment impact using a fibrosis biomarker (FibroTest®) and elastography (FibroScan®).
### Background & Aims The first aim was to extend the validation of FibroTest…
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Metabolic dysfunction-associated steatotic liver disease (MASLD) biomarkers and progression of lower limb arterial calcification in patients with type 2 diabetes: a prospective cohort study. Key publication
…In multivariate analysis, the FibroTest® score remained independently associated with the annualized…
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Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference. Key publication
…0.878 (0.864-0.892) for FibroTest and fibrosis stages, 0…
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Validation of liver fibrosis biomarker (FibroTest) for assessing liver fibrosis progression: proof of concept and first application in a large population.
…Non-invasive biomarkers such as FibroTest (FT) should allow the estimation of…
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FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest.
…The FIB-4 index was strongly correlated to the FibroTest results for…
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Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience. Key publication Review
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Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis.
### Background FibroTest (FT) is the most frequently used serum fibrosis marker and…
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Liver fibrosis markers in alcoholic liver disease. Review
…Among these tests, Fibrotest, FibrometerA and Hepascore demonstrated excellent diagnostic accuracy in…
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Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.
…Patient outcomes worsened as liver stiffness and FibroTest values increased. Prognostic values…
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The Diagnostic Value of FibroTest and Hepascore as Non-Invasive Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC).
…The Hepascore and FibroTest were calculated using specific algorithms. The ANOVA rank…
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Systematic review with meta-analysis: direct comparisons of biomarkers for the diagnosis of fibrosis in chronic hepatitis C and B. Meta Analysis
…0.06(0.02-0.09)], FibroTest vs. APRI [0.05 (0…
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FibroTest-FibroSURE: towards a universal biomarker of liver fibrosis?
…These include FibroTest (BioPredictive) for the quantitative assessment of fibrosis, and ActiTest…
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Assessment of liver fibrosis: noninvasive means.
…Two alternatives to liver biopsy were the most evaluated FibroTest and Fibroscan…
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Methodological aspects of the interpretation of non-invasive biomarkers of liver fibrosis: a 2008 update. Key publication Review
This review summarizes the methodological aspects of the interpretation of non-invasive…
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Prognostic value of liver fibrosis and steatosis biomarkers in type-2 diabetes and dyslipidaemia.
…In type-2 diabetes, FibroTest predicted cardiovascular events and improved the Framingham…
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Reproducibility of non-invasive fibrosis biomarkers, FibroMeter and FibroTest, could be improved by respecting the analytical standardizations.
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Comparison of three algorithms of non-invasive markers of fibrosis in chronic hepatitis C.
…Three algorithms based on the combination of Fibrotest, Forns' index and AST…
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Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus.
…Patients' prognosis decreased as liver stiffness and FibroTest increased. In multivariate analysis…
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Appropriate evidence-based data overviews demonstrate the diagnostic and prognostic performances of FibroTest in patients with chronic hepatitis C.
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Serum bile acid levels as a predictor for the severity of liver fibrosis in patients with chronic hepatitis C.
…its comparison to the patients' FibroTest scores. Two-thirds (90/135 patients…
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[Alpha 2 macroglobulin immunoturbidimetric assays (DakoCytomation reagents) on Roche Diagnostic analysers (Modular P, Cobas Integra). Application to FibroTest-Actic-Test].
…since it was introduced into FibroTest-ActiTest-Fibro (FT-AT-Fibro) algorithm…
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The effectiveness of noninvasive biomarkers to predict hepatitis B-related significant fibrosis and cirrhosis: a systematic review and meta-analysis of diagnostic test accuracy. Meta Analysis
…The areas under the SROC curve for APRI, FIB-4, and FibroTest…
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FibroTest-ActiTest as a non-invasive marker of liver fibrosis. Key publication Meta Analysis
…Indeed, the prognostic performance of FibroTest was at least as accurate as…
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Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
…GBT, HA, APRI, FibroTest, Fib-4, and TE detected F01 from F234…
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Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes. Key publication
…The primary aim was to compare the diagnostic performances of FibroTest in…
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Evaluation and improvement of a reliable diagnosis of cirrhosis by blood tests.
…68.5% versus FibroTest: 37.1%. Using 95% PPV, the cirrhosis detection…
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A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C. Key publication
### Background FibroTest, a noninvasive method of measuring biomarkers of liver fibrosis, is…
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Diagnostic value of serum protein profiling by SELDI-TOF ProteinChip compared with a biochemical marker, FibroTest, for the diagnosis of advanced fibrosis in patients with chronic hepatitis C.
### Background FibroTest has been validated for the diagnosis of liver fibrosis in…
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Fibrotest-Actitest: the biochemical marker of liver fibrosis--the Israeli experience.
### Background The Fibrotest-Actitest is a six-parameter scoring system that allows…
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Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease. Key publication
…Results from the ELF and FibroTest did not differ significantly from those…
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Prospective noninvasive analysis of hepatic fibrosis in patients with Crohn's disease: correlation of transient elastography and laboratory-based markers.
…r=0.33949; fibrotest/APRI: r=0.52937; fibrotest/Forns: r=0…
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Changes of non-invasive markers and FibroScan values during HCV treatment.
…Liver fibrosis was staged with FibroScan and Fibrotest at inclusion, then every…
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Analytical variability of the Fibrotest proteins.
### Objectives The analytical variability of the Fibrotest (FT) parameters raises the issue…
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HCV-GenoFibrotest: a combination of viral, liver and genomic (IL28b, ITPA, UGT1A1) biomarkers for predicting treatment response in patients with chronic hepatitis C.
…The hypothesis was that fibrosis stage estimated with FibroTest instead of biopsy…
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Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes. Key publication
…The performances of the FibroTest, NashTest-2 and SteatoTest-2 were assessed…
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Diagnostic performance of FibroTest-ActiTest, transient elastography, and the fibrosis-4 index in patients with autoimmune hepatitis using histological reference. Key publication
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Non-invasive markers of liver fibrosis in chronic liver disease in a group of Mexican children. A multicenter study.
…The aim of this study was to evaluate Fibrotest® score and APRI…
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Non-invasive measurement of liver and pancreas fibrosis in patients with cystic fibrosis.
…lobe, ARFI-left-liver-lobe, Fibrotest, Fibrotest-corrected-by-haptoglobin was 17…
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Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study.
…FIB-4 0.732 AUC and FibroTest 0.715 AUC indicated advanced…
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The predictive value of Fibrotest vs. APRI for the diagnosis of fibrosis in chronic hepatitis C.
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Diagnostic accuracy of the fibrotest in hemodialysis and renal transplant patients with chronic hepatitis C virus.
…In all, 75% of patients were correctly classified using the fibrotest. If…
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Non-invasive evaluation of the liver disease severity in children with chronic viral hepatitis using FibroTest and ActiTest - comparison with histopathological assessment.
…chronic viral hepatitis using the FibroTest and ActiTest (FT/AT), and compare…
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Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis.
…The abnormal results of Fibrotest were reported in 15% of patients (12…
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Screening for liver fibrosis by using FibroScan(®) and FibroTest in patients with diabetes.
…Severe fibrosis was predicted when FibroTest was >0.59 or liver stiffness…
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Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C.
…ratio (APRI), Forns' index and Fibrotest at the time of liver biopsy…
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Liver stiffness measurement in children using FibroScan: feasibility study and comparison with Fibrotest, aspartate transaminase to platelets ratio index, and liver biopsy.
…FibroScan, Fibrotest, and APRI, and, when necessary, a liver biopsy (n = 33…
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Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control study.
…as transient elastography (FibroScan) and FibroTest could be useful for monitoring MTX…
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Poynard T, Imbert-Bismut F, Ratziu V, Myers RP, Di Martino V, Thabut D, Moussalli J, Benhamou Y
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Real-Time Shear Wave versus Transient Elastography for Predicting Fibrosis: Applicability, and Impact of Inflammation and Steatosis. A Non-Invasive Comparison.
…unmet needs. ### Methods We took FibroTest as the fibrosis reference and ActiTest…
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Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C.
…In 2001, FibroTest ActiTest (FT-AT), a panel of biochemical markers, was…
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Intra-individual fasting versus postprandial variation of biochemical markers of liver fibrosis (FibroTest) and activity (ActiTest).
…total bilirubin (all part of FibroTest) plus alanine aminotransferase (all part of…
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Usefulness of noninvasive tests in nodular regenerative hyperplasia of the liver.
…All patients had liver stiffness (using FibroScan) and FibroTest measurements. Magnetic resonance…
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Screening studies of transient elastography and FibroTest in the general population.
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Discordance between biochemical markers of liver activity and fibrosis (Actitest-Fibrotest) and liver biopsy in patients with chronic hepatitis C.
…Clinicians must interpret Actitest and Fibrotest results with caution in patients with…
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Effective use of FibroTest to generate decision trees in hepatitis C.
### Aim To assess the usefulness of FibroTest to forecast scores by constructing…
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Predicting significant fibrosis in hepatitis C patients in Luxembourg using serological markers.
…putatively associated with liver fibrosis. Fibrotest and Forns scores were compared with…
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Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
…Using logistic regression, statistical independence was demonstrated for MP3, Fibrotest and APRI…
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Evaluation of FibroTest inter-laboratory variations requires standardization on analytical systems and should not be mixed with underpowered histological validation.
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FibroMAX: towards a new universal biomarker of liver disease? Review
…risk of chronic liver diseases: FibroTest (BioPredictive) for the quantitative assessment of…
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The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B.
…biopsies and with 372 synchronous FibroTest performed either in France or in…
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Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data. Meta Analysis
…non-invasive markers of fibrosis (FibroTest), steatosis (SteatoTest) and steato-hepatitis (NashTest…
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Toward non-invasive assessment strategies in autoimmune hepatitis.
…This study evaluates the diagnostic performance of FibroTest-Actitest, transient elastography, and…
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European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD) and European Association for the Study of Obesity (EASO) clinical practice recommendations for the management of non-alcoholic fatty liver disease: evaluation of their application in people with Type 2 diabetes.
…fibrosis score, and SteatoTest and FibroTest scores were determined. ### Results According to…
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The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases.
…Performance of Fibrotest-Fibrosure was good in all aetiologies for both ≥F2…
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Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis C.
…reference histological result) rates were: Fibrotest: 17.2%, FibroMeter2G: 5.6%, local…
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Performance of the FibroTest cannot be accurately estimated in nine paediatric patients with advanced fibrosis.
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Comparison of non-invasive fibrosis markers and classical liver biopsy in chronic hepatitis C.
…The mean scores of FibroTest, FIB4, APRI, and AP index were significantly…
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Comparison of acoustic radiation force impulse imaging with transient elastography for the detection of complications in patients with cirrhosis.
…ARFI-imaging of the liver and spleen, TE and Fibrotest were performed…
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Fibroscan and FibroTest/FibroMax to assess liver fibrosis/cirrhosis in patients with chronic HBV and HCV infection in Georgia.
…In patients with chronic HCV or HBV infection Fibroscan and Fibrotest/FibroMax…
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Improved inflammatory activity with peginterferon alfa-2b maintenance therapy in non-cirrhotic prior non-responders: a randomized study.
…Both FibroTest and ActiTest were significantly improved during maintenance therapy.
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Screening studies of transient elastography and FibroTest in the general population - Authors' reply.
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Sequential algorithms combining non-invasive markers and biopsy for the assessment of liver fibrosis in chronic hepatitis B.
…The performance of these methods and of sequential algorithms combining Fibrotest, APRI…
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Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics.
…The fibrosis stage was evaluated on the basis of FibroTest. The values…
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Successful treatment with telaprevir-based regimens for chronic hepatitis C results in significant improvements to serum markers of liver fibrosis.
…Scores from four biomarker tests, FibroTest, APRI, FIB-4 and Forns' Score…
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Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease.
…M and XL probes and FibroTest in the staging of fibrosis in…
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Letter: FibroTest for staging fibrosis in non-alcoholic fatty liver disease.
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FibroTest has better diagnostic and prognostic values than the aspartate aminotransferase-to-platelet ratio index in patients with chronic hepatitis C.
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[Results transferability on RXL, ARX, X-Pand, BN2 (Dade Behring) and modular DP (Roche Diagnostics) analysers: application to component assays of fibrotest and Actitest].
…Moreover, we verified the transferability of Fibrotest and Actitest results between the…
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Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus. Key publication
The aim was to assess the utility of FibroTest-ActiTest (FT-AT…
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Prediction of liver histological lesions with biochemical markers in patients with chronic hepatitis B.
…Fibrotest accurately predicted F2-F4 fibrosis (AUROC, 0.78+/-0.04). Fibrotest…
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Development and validation of a nomogram based on clinical factors and standard laboratory tests for prediction of clinically significant liver fibrosis in chronic hepatitis C virus infection.
…Compared with FibroTest, Fibro-Nomogram performed slightly better at predicting severe fibrosis…
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[The diagnostic value of non-invasive biochemical biomarkers in alcohol abuse].
…SteatoTest, FibroTest and AshTest. The aim of the study was to evaluate…
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Intermethod calibration of alanine aminotransferase (ALT) and gamma-glutamyltransferase (GGT) results: application to Fibrotest and Actitest scores.
Two multi-component scores (Fibrotest and Actitest) have been proposed to evaluate…
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Evaluating the accuracy and increasing the reliable diagnosis rate of blood tests for liver fibrosis in chronic hepatitis C.
…0.853, Fibrotest: 0.811, Fib-4: 0.799, aspartate aminotransferase to…
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Performance of 11 biomarkers for liver fibrosis assessment in HIV/HBV co-infected patients.
…The AUROCs of the Fibrotest, Hepascore, Fibrometer, and Zeng's scores ranged…
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Performance of noninvasive markers for liver fibrosis is reduced in chronic hepatitis C with normal transaminases.
…Overall, Fibrotest had the best performance in NALT group, as showed by…
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Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease.
…fibrosis markers such as the FibroTest (FT) are established methods for the…
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Study on noninvasive laboratory tests for fibrosis in chronic HBV infection and their evaluation.
…The FibroTest index had the largest area under the receiver operating characteristic…
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Assessment of methotrexate hepatotoxicity in psoriasis patients: a prospective evaluation of four serum fibrosis markers.
…PIIINP and Fibrotest were stable in all groups. ### Conclusion The fibrosis markers…
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Noninvasive biomarkers FibroTest and ActiTest versus liver biopsy in chronic hepatitis C patients: the Middle East experience.
### Background The aim of this study was to compare noninvasive biomarkers, FibroTest…
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Biomarkers for liver disease in urea cycle disorders.
…Interestingly, liver stiffness did not correlate with ultrasound appearance or FibroTest™. ### Conclusion…
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Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C. Review
…90.1, 100%, Fibrotest: 78.2, 95.1%, Hepascore: 73.8, 94…
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Systematic review: Investigating the prognostic performance of four non-invasive tests in alcohol-related liver disease.
…Fibrosis [ELF] test, FibroScan, and FibroTest) in ArLD. ### Methods Applying systematic review…
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Applicability and precautions of use of liver injury biomarker FibroTest. A reappraisal at 7 years of age.
### Background FibroTest (FT) is a validated biomarker of fibrosis. To assess the…
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Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.
…The analyses of ActiTest and FibroTest had been prospectively scheduled. The primary…
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Altered serum N-glycomics in chronic hepatitis B patients.
…However, GlycoFibroTest (AUC=0.740) was slightly better than FibroTest (AUC=0…
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Prospective direct comparison of non-invasive liver tests in outpatients with type 2 diabetes using intention-to-diagnose analysis. Key publication
…The Nash-FibroTest panel including FibroTest-T2D, SteatoTest-T2D and MashTest-T2D…
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Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C; results from a cohort of 446 patients.
…The association that included Fibrotest was also reliable for the improvement of…
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The predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and Forns index to noninvasively estimate fibrosis in hepatitis C and nonhepatitis C liver diseases.
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An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load. Key publication
…The use of FibroTest (FT) and ActiTest (AT), biomarkers of fibrosis and…
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Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases.
…and the artificial intelligence algorithm FibroTest. METAVIR fibrosis scores were analyzed in…
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Concordance of non-invasive serology-based scoring indices and transient elastography for liver fibrosis and cirrhosis in chronic hepatitis C.
…We propose that FIB-4 score, Fibrotest and GUCI be used in…
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Transient elastography and other noninvasive tests to assess hepatic fibrosis in patients with viral hepatitis. Review
…Among serum indices, Fibrotest has been the most extensively studied and validated…
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Evaluation of FibroTest-ActiTest in children with chronic hepatitis C virus infection. Key publication
FibroTest-ActiTest (FT-AT) has been validated in adults with chronic hepatitis…
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Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference. Key publication
…A combination of NIT-NASHs with FibroTest (AUROC=0.800; 0.759…
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Noninvasive assessment of hepatic fibrosis and necroinflammatory activity in Egyptian children with chronic hepatitis C virus infection using FibroTest and ActiTest.
…In this study, we aimed to prospectively validate FibroTest (FT) and ActiTest…
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Biomarkers as a first-line estimate of injury in chronic liver diseases: time for a moratorium on liver biopsy?
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Performance of the SteatoTest, ActiTest, NashTest and FibroTest in a multiethnic cohort of patients with type 2 diabetes mellitus.
…Regarding the FibroTest score, its performance to identify patients with moderate or…
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Noninvasive prediction of fibrosis in patients with chronic hepatitis C.
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Letter: FibroTest for staging fibrosis in non-alcoholic fatty liver disease - authors' reply.
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Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study.
…Obuchowski's measure showed Fibrometer® (0.86), Fibrotest® (0.84), Hepascore® (0…
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Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. Key publication
…hepatitis and alcoholic liver disease (FibroTest, FT), in patients with NAFLD. ### Methods…
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Validation of Ten Noninvasive Diagnostic Models for Prediction of Liver Fibrosis in Patients with Chronic Hepatitis B.
…APAG, APRI, FIB-4 and FibroTest) was assessed against the liver histology…
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Spleen stiffness measurement by transient elastography to diagnose portal hypertension in children.
…Liver stiffness measurements and Fibrotest did not reflect the presence or degree…
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Slow regression of liver fibrosis presumed by repeated biomarkers after virological cure in patients with chronic hepatitis C.
…Using biopsy as reference, FibroTest™ has been validated as a biomarker of…
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Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest™) and transient elastography (FibroScan®).
### Background & Aims FibroTest™ (FT) and Transient Elastography (TE) have been validated as…
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A prospective assessment of the inter-laboratory variability of biochemical markers of fibrosis (FibroTest) and activity (ActiTest) in patients with chronic liver disease.
…Biochemical markers for liver fibrosis (FibroTest) and necroinflammatory features (ActiTest) are an…
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Diagnostic value of FibroTest with normal serum aminotransferases.
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Non-invasive diagnosis of steatosis, inflammatory changes and liver fibrosis in patients with non-alcoholic fatty liver diseases. Pilot study.
…SteatoTest, ActiTest and FibroTest. We compared the prevalence of metabolic disorders and…
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Complex non-invasive fibrosis models are more accurate than simple models in non-alcoholic fatty liver disease.
…APRI, BARD) and complex (Hepascore, Fibrotest, FIB4) fibrosis models were calculated in…
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FibroTest/Fibrosure for significant liver fibrosis and cirrhosis in chronic hepatitis B: a meta-analysis. Meta Analysis
…Noninvasive alternatives such as FibroTest/Fibrosure (FT) have been developed in order…
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Biomarkers of liver fibrosis. Review
…patented and five were patented. FibroTest (FT) was the most studied test…
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Utility of noninvasive methods for the characterization of nonalcoholic liver steatosis in the family practice. The "VARES" Italian multicenter study.
…circumference, ALT, triglycerides, and FLI. Fibrotest correlated only with ALT. FLI identified…
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Liver fibrosis in young Egyptian beta-thalassemia major patients: relation to hepatitis C virus and compliance with chelation.
…and transient elastography (TE) (FibroScan). FibroTest and liver biopsy were done to…
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FibroTest is an independent predictor of virologic response in chronic hepatitis C patients retreated with pegylated interferon alfa-2b and ribavirin in the EPIC³ program.
…The aim of the present study was to assess FibroTest (FT), a…
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Optimization and robustness of blood tests for liver fibrosis and cirrhosis.
…2G), but not those of Fibrotest and Hepascore, and provided a hyaluronate…
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Use of Non-invasive Testing to Stage Liver Fibrosis in Patients with HIV. Review
…markers) such as APRI, FIB4, FibroTest, FibroSpect II, HepaScore, or imaging-based…
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SAFE biopsy: a validated method for large-scale staging of liver fibrosis in chronic hepatitis C.
…to-platelet ratio index and Fibrotest-Fibrosure, thereby limiting liver biopsy to…
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Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy.
…TE, APRI and Fibrotest did not significantly change during follow-up. There…
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Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity.
…of noninvasive markers of fibrosis (FibroTest), steatosis (SteatoTest), and steatohepatitis (NashTest, ActiTest…
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Hepatocyte-derived biomarkers predict liver-related events at 2 years in Child-Pugh class A alcohol-related cirrhosis.
…Patients with both keratin-18 concentrations >285 U/L and FibroTest >0…
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Meta-analyses of FibroTest diagnostic value in chronic liver disease. Key publication Meta Analysis
### Background FibroTest (FT) is a biomarker of liver fibrosis initially validated in…
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Implementing non-invasive markers for liver fibrosis in clinical practice.
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Study of FibroTest and hyaluronic acid biological variation in healthy volunteers and comparison of serum hyaluronic acid biological variation between chronic liver diseases of different etiology and fibrotic stage using confidence intervals.
### Objectives Personalized ranges of liver fibrosis serum biomarkers such as FibroTest or…
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Prevalence of liver fibrosis and cirrhosis in 699 Moroccan patients with chronic hepatitis C.
…a non-invasive blood test (FibroTest and ActiTest) was studied in 699…
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Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali.
…Fibrosis and hepatitis activity were measured using the Fibrotest-Actitest. A mutation…
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FibroTest is effective in patients with normal transaminases, when accuracy is standardized on fibrosis stage prevalence.
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Variability in definitions of transaminase upper limit of the normal impacts the APRI performance as a biomarker of fibrosis in patients with chronic hepatitis C: "APRI c'est fini ?".
…of 1651 patients with APRI, FibroTest and biopsy. ### Results The overview, and…
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Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.
…This study compares the concurrent diagnostic performances of LSM and FibroTest using…
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Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B.
### Background And Aims Diagnostic values of FibroTest (FT) for hepatic fibrosis have…
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Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials.
…including the SteatoTest, NashTest and FibroTest) through three randomized sham controlled studies…
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Diagnosis of fibrosis and cirrhosis. Liver biopsy is not always necessary. Review
…With the manufacturers' recommended cutoff values, FibroTest identifies about 70% of patients…
-
Nonalcoholic fatty liver disease in chronic obstructive pulmonary disease.
…SteatoTest, NashTest and FibroTest) were used to assess steatosis, nonalcoholic steatohepatitis (NASH…
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Comparison of liver stiffness, fibrotest and liver biopsy for assessment of liver fibrosis in kidney-transplant patients with chronic viral hepatitis.
To assess the accuracy of the noninvasive tools, fibrotest (FT) and liver…
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Clinical applicability of non-invasive markers for liver fibrosis in chronic hepatitis C (Letter)
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Editorial: FibroTest to predict liver-related mortality in NAFLD. Should this change the diagnostic algorithm in NAFLD?
-
Independent prospective multicenter validation of biochemical markers (fibrotest-actitest) for the prediction of liver fibrosis and activity in patients with chronic hepatitis C: the fibropaca study. Key publication
### Objectives Fibrotest (FT) and Actitest (AT) are biochemical markers of fibrosis and…
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Peta V, Ziol M, Imbert-Bismut F, et al., for the FibroFrance-GHPS-HECAM group
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Severity of Fontan-Associated Liver Disease Correlates with Fontan Hemodynamics.
…Liver stiffness values and Fibrotest^®^ scores correlated significantly with Fontan duration (P…
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A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.
…HD-UDCA significantly reduced the FibroTest® serum fibrosis marker (p<0.001…
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FIB-4: a simple, inexpensive and accurate marker of fibrosis in HCV-infected patients.
-
Current Possibilities to Assess the Degree of Liver Fibrosis in Patients with Haemophilia Infected with HCV--Review. Review
…relevant blood parameters (e.g. FibroTest, Fibrometer, APRI index). Ease of implementation…
-
Combination of fibrosis tests: sequential or synchronous?
-
Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.
…The areas under the receiver operating characteristic (ROC) curve of FibroScan, FibroTest…
-
Noninvasive procedures to evaluate liver involvement in HIV-1 vertically infected children.
…Liver function was assessed with standard serum biochemical markers, FibroTest, ActiTest, SteatoTest…
-
Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review.
…platelet ratio index (APRI), FibroIndex, FibroTest, and Forns index had median positive…
-
Non-invasive diagnostic assessment tools for the detection of liver fibrosis in patients with suspected alcohol-related liver disease: a systematic review and economic evaluation.
…Three studies of FibroTest, no relevant studies of FibroMax, and six studies…
-
Prospective evaluation of FibroTest®, FibroMeter®, and HepaScore® for staging liver fibrosis in chronic hepatitis B: comparison with hepatitis C.
…describe the diagnostic performance of FibroTest®, FibroMeter®, and HepaScore® for liver fibrosis…
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External Validation of LCR1-LCR2, a Multivariable Hepatocellular Carcinoma Risk Calculator, in a Multiethnic Cohort of Patients With Chronic Hepatitis B. Key publication
### Background And Aims The liver cancer risk test (LCR1-LCR2) is a…
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Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review.
…Only transient elastography and FibroTest were compared with histological endpoints. The prevalence…
-
Comparison of noninvasive models of fibrosis in chronic hepatitis B.
…examined noninvasive fibrosis models [Hepascore, Fibrotest, APRI, hepatitis e antigen (HBeAg)-positive…
-
Reproducibility of blood tests of liver fibrosis in clinical practice.
…FibroMeter, Fibrotest, APRI and their composites variables. ### Design And Methods Four studies…
-
[The value of noninvasive serological markers in hepatitis B]. Review
…The combination of any of these methods (particularly the FibroTest) with transient…
-
Non-invasive Investigations for the Diagnosis of Fontan-Associated Liver Disease in Pediatric and Adult Fontan Patients.
…hepatic integrity and function, the FibroTest, liver ultrasound, and transient elastography (FibroScan…
-
Non-invasive assessment of liver fibrosis: are we ready?
-
Transient elastography and biomarkers for liver fibrosis assessment and follow-up of inactive hepatitis B carriers.
…6.8 kPa, P < 0.0001), Fibrotest (0.16 vs. 0.35…
-
The Distribution of Liver Steatosis, Fibrosis, Steatohepatitis and Inflammation Activity in Alcoholics According to FibroMax Test.
…fibrosis by FibroTest, steatosis by SteatoTest, steatohapatitis by AshTest (alcoholic origin) and…
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Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.
…TRIO were assessed for fibrosis [FibroTest; FibroScan; fibrosis-4 index (FIB-4…
-
Discordance between liver biopsy and FibroTest in assessing liver fibrosis in chronic hepatitis B.
### Background And Aims The FibroTest (FT) demonstrated excellent diagnostic performance in the…
-
A brief review on molecular, genetic and imaging techniques for HCV fibrosis evaluation. Review
…invasive serum markers for HCV, FibroTest, Forn's Index, Fibrometer and HepaScore…
-
Evolution of biomarkers of liver fibrosis and liver insufficiency in hepatitis C virus-infected patients treated with pegylated interferon plus ribavirin and rituximab.
…in patients treated without RTX. FibroTest values decreased from 0.70 at…
-
Biopsy as well as FibroTest/Fibrosure is suboptimal for discriminating intermediate fibrosis stages in patients with chronic hepatitis B.
-
Efficacy and safety of tenofovir disoproxil fumarate in Asian-Americans with chronic hepatitis B in community settings.
…The percentage of patients with F0 (no or minimal) fibrosis by FibroTest…
-
[The prediction and validation of liver fibrosis by a noninvasive model and validation in patients with chronic hepatitis B].
### Objective To develop a simple model for the noninvasive diagnosis of liver…
-
A novel panel of blood markers to assess the degree of liver fibrosis.
…Measurements included 51 blood markers and Fibrotest, Fibrospect, ELFG, APRI, and Forns…
-
Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection.
-
Comparison of liver fibrosis blood tests developed for HCV with new specific tests in HIV/HCV co-infection.
…0.722, Fibrotest: 0.778, Hepascore: 0.779, FibroMeter: 0.783, HICV…
-
Diagnostic accuracy of the Coopscore© to predict liver fibrosis in human immunodeficiency virus/hepatitis B virus co-infection.
…Coopscore^©^, Fibrotest®, Fibrometer®, Hepascore® and Zeng score were computed and compared with…
-
Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest).
### Background FibroTest and elastography have been validated as biomarkers of liver fibrosis…
-
Transient Elastography for Assessment of Liver Fibrosis and Steatosis: An Evidence-Based Analysis. Review
…Acoustic force radiation impulse and FibroTest were not superior to transient elastography…
-
Applicability and variability of liver stiffness measurements according to probe position.
…The discordance rate between the reference position result and FibroTest was higher…
-
Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C.
…either transient elastography (TE) and Fibrotest (FT) (Castera) or AST-to-Platelet…
-
Screening for liver fibrosis by using a noninvasive biomarker in patients with diabetes.
…with a noninvasive fibrosis biomarker (FibroTest) in patients with diabetes. ### Methods We…
-
Prognostic value of the combined use of transient elastography and fibrotest in patients with chronic hepatitis B.
### Background & Aims Liver stiffness (LS) measurement using transient elastography and the FibroTest…
-
Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomics.
…In combination with the clinical chemistry-based Fibrotest biomarker, compensated cirrhosis was…
-
Non-invasive evaluation of liver fibrosis by transient elastography and biochemical markers in elderly inpatients.
…ratio index [APRI], Forns score, FibroTest). Three groups of patients were included…
-
Novel Biomarkers of Grade I Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease.
…was positively associated with age, Fibrotest, α2-macroglobulin, epicardiac adipose tissue (EAT…
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A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C.
…Fibroscan, Fibrotest, FibroMeter, Hepascore, FIB-4, APRI. ### Results Exploratory set: Fibroscan and…
-
Fibrotest or Fibroscan for evaluation of liver fibrosis in haemophilia patients infected with hepatitis C.
…Previous studies found a high rate of significant fibrosis both by Fibrotest…
-
Improving estimation of liver fibrosis using combination and newer noninvasive biomarker scoring systems in hepatitis C-infected haemophilia patients.
…In our hepatitis C-infected haemophilia patients, Fibrotest (FT) correctly identified clinically…
-
Evolving practices of non-invasive markers of liver fibrosis in patients with chronic hepatitis C in France: time for new guidelines?
-
The diagnostic value of combining carbohydrate-deficient transferrin, fibrosis, and steatosis biomarkers for the prediction of excessive alcohol consumption.
…An algorithm combining the percentage of CDT, FibroTest and SteatoTest permitted to…
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Usefulness of acoustic radiation force impulse and fibrotest in liver fibrosis assessment after liver transplant.
…AUC for Fibrotest was 0.848 in discriminating patients with Ishak fibrosis…
-
Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease.
…surrogate for IR) and fibrosis (FibroTest>0.48 as a surrogate for…
-
Concordance in a world without a gold standard: a new non-invasive methodology for improving accuracy of fibrosis markers.
…Non-invasive techniques, liver stiffness measurements (LSM) and biomarkers [FibroTest(R) (FT…
-
Diffusion-weighted magnetic resonance imaging for the assessment of fibrosis in chronic hepatitis C.
…0.79 (+/-0.08) for FibroTest, 0.87 (+/-0.06) for the…
-
Screening for liver disease using non-invasive biomarkers (FibroTest, SteatoTest and NashTest) in patients with hyperlipidaemia.
…use the non-invasive biomarkers, FibroTest (FT), SteatoTest and NashTest, and to…
-
The role of the non-invasive serum marker FibroTest-ActiTest in the prediction of histological stage of fibrosis and activity in children with naïve chronic hepatitis B infection.
…the non-invasive serum marker FibroTest-ActiTest (FT-AT) reliably predicts the…
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The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests.
…Data collected included anthropometrics, biochemistry, adiponectin, SteatoTest™, NashTest™, FibroTest™, OWLiver® test and…
-
The diagnostic value of biomarkers (AshTest) for the prediction of alcoholic steato-hepatitis in patients with chronic alcoholic liver disease. Key publication
…AshTest was constructed using a combination of the six components of FibroTest…
-
Variability of the area under the receiver operating characteristic curves in the diagnostic evaluation of liver fibrosis markers: impact of biopsy length and fragmentation.
…The FibroTest area under the ROC curves for the diagnosis of advanced…
-
Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard.
…of fibrosis as compared with FibroTest (FT) and liver stiffness measurement (LSM…
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A prospective assessment of an 'a la carte' regimen of PEG-interferon alpha2b and ribavirin combination in patients with chronic hepatitis C using biochemical markers.
…had two or more RF. FibroTest and ActiTest assessed the impact of…
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Validation of AshTest as a Non-Invasive Alternative to Transjugular Liver Biopsy in Patients with Suspected Severe Acute Alcoholic Hepatitis.
### Background/Aims According to guidelines, the histological diagnosis of severe alcoholic steatohepatitis…
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Comparison of elastography, serum marker scores, and histology for the assessment of liver fibrosis in hepatitis B virus (HBV)-infected patients in Burkina Faso.
…ratio index (APRI), Fib-4, Fibrotest, Fibrometre, and Fibroscan. Elastometric thresholds were…
-
Comparison of test performance profile for blood tests of liver fibrosis in chronic hepatitis C.
…the following tests were evaluated: Fibrotest (FT), APRI, FibroMeter (FM), and Hepascore…
-
Evolution of Non-alcoholic Fatty Liver Disease (NAFLD) Biomarkers in Response to Weight Loss 1 Year After Bariatric Surgery-a Post Hoc Analysis of the FibroTest Prospective Study. Key publication
…Fibrosis assessed by the FibroTest® showed that 82.5% of patients were…
-
The non-invasive assessment of hepatic fibrosis. Review
Hepatic disease accounts for approximately 2 million deaths/year worldwide. Liver fibrosis…
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Stage of liver fibrosis in patients with congenital bleeding disorders and infected with hepatitis C virus.
…Liver fibrosis was measured with shear wave elastography and FibroTest. The risk…
-
FibroTest (FT) has similar accuracy for cirrhosis in 'intention-to-diagnose' which is superior to transient elastography (TE) in chronic hepatitis B.
-
Non-invasive diagnosis and follow-up of chronic infection with Hepatitis C Virus.
…to the value of FibroScan®, Fibrotest® or Fibrometer®. Hepatocellular carcinoma screening must…
-
Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.
…to the markers used in FibroTest, Enhanced Liver Fibrosis (ELF) test, Hepascore…
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Optimized stepwise combination algorithms of non-invasive liver fibrosis scores including Hepascore in hepatitis C virus patients.
…alternative to liver biopsy and Fibrotest (FT) and propose five optimized combination…
-
Longitudinal assessment of histology surrogate markers (FibroTest-ActiTest) during lamivudine therapy in patients with chronic hepatitis B infection.
### Objectives The noninvasive serum markers, FibroTest-ActiTest (FT-AT), are an alternative…
-
Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study.
### Background Steatosis is common in patients with hepatitis C virus (HCV) infection…
-
Systematic review and meta-analysis of the diagnostic accuracy of fibrosis marker panels in patients with HIV/hepatitis C coinfection. Meta Analysis
…4 studies], Forns' [n = 2], FibroTest [n = 1], SHASTA [n = 1]) met…
-
Non-invasive biomarkers of liver fibrosis in haemophilia patients with hepatitis C: can you avoid liver biopsy?
…The most thoroughly evaluated biomarker is the FibroTest (FT) (AUROC 0.80…
-
Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.
### Background And Aims Liver stiffness measurement (LSM) and FibroTest (FT) are frequently…
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The risks of changing the rules for previously validated biomarkers and using the same patients several times. Response letter to Calès et al. Gastroenterol Clin Biol 2008;32:1050-60: "Evaluation and improvement of a reliable diagnosis of cirrhosis by blood tests".
-
FibroStic: a large confirmatory study for non-invasive biomarkers accuracy, if correctly interpreted.
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Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy. Key publication
…groups in comparison with the Fibrotest/Actitest (FT/AT), using the liver…
-
Hepatic and renal end-organ damage in the Fontan circulation: A report from the Australian and New Zealand Fontan Registry.
…Fifty-four patients (54/118, 46%) had a FibroTest score ≥0.49…
-
Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants.
…0.84; FibroTest: SF: 0.86, AF: 0.78; and ELF: AF…
-
Physicians' practices for diagnosing liver fibrosis in chronic liver diseases: a nationwide, Canadian survey.
…France) for 39.4% and Fibrotest (LabCorp, USA) for 7.7%. Etiology…
-
Assessment of liver fibrosis and steatosis in PBC with FibroScan, MRI, MR-spectroscopy, and serum markers.
…No correlation of histologic-stage was observed for FibroTest and AST to…
-
Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C. Key publication
### Background The FibroTest and ActiTest are noninvasive biochemical markers of liver injury…
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Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastography.
…serological indexes (Benlloch, APRI, Forns, Fibrotest and Doppler resistance index), was investigated…
-
Biomarkers for the prediction of liver fibrosis in patients with chronic alcoholic liver disease.
…available liver biopsy examination and FibroTest FibroSure (FT) results were included prospectively…
-
Transient elastography using Fibroscan is the most reliable noninvasive method for the diagnosis of advanced fibrosis and cirrhosis in alcoholic liver disease.
…FS, Fibrotest, FIB-4, aspartate aminotransferase to platelet ratio index (APRI), and…
-
Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population.
…index (HRI) and SteatoTest, whereas FibroTest was used to assess fibrosis degree…
-
Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases.
…markers of fibrosis (APRI, FORNS, FibroTest and hyaluronic acid). The dynamic profiles…
-
Awareness of the severity of liver disease re-examined using software-combined biomarkers of liver fibrosis and necroinflammatory activity.
…The global database of the FibroTest-ActiTest, including 1,085,657 subjects…
-
Commentary: prognostication of chronic hepatitis B--are Fibrotest and Fibroscan the final answers?
-
Combination of blood tests for significant fibrosis and cirrhosis improves the assessment of liver-prognosis in chronic hepatitis C.
…tests targeting fibrosis (APRI, FIB4, Fibrotest, Hepascore, FibroMeter) or cirrhosis (CirrhoMeter) were…
-
Noninvasive Assessment of Liver Fibrosis.
…TE (FibroScan®), FibroTest® and APRI have been the most extensively studied and…
-
Fibromax-based nonalcoholic fatty liver disease in chronic obstructive pulmonary disease patients with obstructive sleep apnea: Methodological considerations.
…the FibroTest, SteatoTest and NashTest, from the Fibromax® panel. Among the main…
-
LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis. Key publication
### Background No blood test has been shown to be effective in the…
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Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes.
…based biomarkers for liver fibrosis (FibroTest, NAFLD fibrosis score, BARD score, and…
-
Validation of biochemical markers for the prediction of liver fibrosis and necroinflammatory activity in hemodialysis patients with chronic hepatitis C.
…Our purpose was to compare the accuracy of the FibroTest (FT) and…
-
The Association of Histologic and Noninvasive Tests With Adverse Clinical and Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.
…ELF, ≥10.43; Nonalcoholic Fatty Liver Disease Fibrosis Score, ≥1.80; Fibrotest…
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Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores.
…index (PI), platelet count (PC), FibroTest (FT) and Lok index). ### Methods All…
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Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients.
…0.79 and 0.70 (FibroTest), 0.78 and 0.71 (FIB…
-
Hepatitis B: are non-invasive markers of liver fibrosis reliable? Review
…of false positive results with FibroTest in patients with Gilbert's syndrome…
-
Profiles of liver fibrosis evolution during long-term tenofovir treatment in HIV-positive patients coinfected with hepatitis B.
…From data on non-invasive liver fibrosis assessments collected yearly (FibroTest®), we…
-
Diagnostic algorithms for liver fibrosis in hepatitis C: are they ready to avoid liver biopsy?
-
Comparison of transient elastography (FibroScan), FibroTest, APRI and two algorithms combining these non-invasive tests for liver fibrosis staging in HIV/HCV coinfected patients: ANRS CO13 HEPAVIH and FIBROSTIC collaboration.
…We compared the performances of transient elastography (TE), Fibrotest (FT), the aspartate…
-
Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study).
### Background & Aims The diagnostic accuracy of non-invasive liver fibrosis tests that…
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Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy.
…transient elastography (Fibroscan™) and blood tests (Fibrometer®, Fibrotest®, and Hepascore®). In this…
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ActiTest accuracy for the assessment of histological activity grades in patients with chronic hepatitis C, an overview using Obuchowski measure. Meta Analysis
### Background ActiTest (AT) is a biomarker of liver necro-inflammatory histological activity…
-
Non-invasive diagnosis of hepatitis B virus-related cirrhosis. Review
Chronic hepatitis B (CHB) infection is a major public health problem associated…
-
An Invisible Early Steatosis Phenotype Defined for a Large Population-Based Cohort.
**Background:** The current definition of metabolic dysfunction-associated steatotic liver disease (MASLD…
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Comparative assessment of liver fibrosis by computerized morphometry in naïve patients with chronic hepatitis B and C.
…In F ≤ 2 patients, correlation between FR and Fibrotest(®) was only significant…
-
EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. Key publication
-
[FibroTest-ActiTest for predicting liver fibrosis and inflammatory activity in Chinese patients with chronic hepatitis B].
### Objective To confirm the diagnostic value of FibroTest-ActiTest (FT-AT) in…
-
Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. Review
Alcoholic liver disease (ALD) consists of a broad spectrum of disorders, ranging…
-
Standardization of ROC curve areas for diagnostic evaluation of liver fibrosis markers based on prevalences of fibrosis stages. Key publication
…standardization. ### Methods The AUCs of FibroTest (FT) for the diagnosis of advanced…
-
Factors to improve the management of hepatitis C in drug users: an observational study in an addiction centre.
…In 2003 and 2004, 224 patients were assessed with Fibrotest-Actitest on…
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Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers.
…elastography (TE) and serum biomarkers (Fibrotest [FT]). ### Methods In 202 consecutive HIV…
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Role of genotype G hepatitis B virus mixed infection on the progression of hepatic fibrosis in HIV positive patients over 5 years of follow-up.
…by a non invasive biomarker (Fibrotest), was evaluated first, by a cross…
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First-line assessment of patients with chronic liver disease with non-invasive techniques and without recourse to liver biopsy.
-
The diagnostic value of biomarkers (SteatoTest) for the prediction of liver steatosis. Key publication
…SteatoTest was constructed using a combination of the 6 components of FibroTest…
-
Diagnostic Accuracy of Noninvasive Markers of Steatosis, NASH, and Liver Fibrosis in HIV-Monoinfected Individuals at Risk of Nonalcoholic Fatty Liver Disease (NAFLD): Results From the ECHAM Study.
…All had hepatic MRI-PDFF, FibroScan/CAP, FibroTest/NashTest/SteatoTest, APRI, FIB…
-
Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography.
### Objective Patients with short bowel syndrome (SBS) receiving long-term parenteral nutrition…
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Noninvasive methods, including transient elastography, for the detection of liver disease in adults with cystic fibrosis.
…platelet ratio index (APRI) and FibroTest (FT) scores were also calculated. The…
-
Performance of serum apolipoprotein-A1 as a sentinel of Covid-19. Key publication
### Background Since 1920, a decrease in serum cholesterol has been identified as…
-
Non-invasive markers for hepatic fibrosis. Review
…and serum-based APRI and FibroTest. There are many other tests that…
-
Noninvasive assessment of portal hypertension in patients with cirrhosis. Review
Severe portal hypertension is responsible for complications and death. Although measurement of…
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Noninvasive Testing for Nonalcoholic Steatohepatitis and Hepatic Fibrosis in Patients With Psoriasis Receiving Long-term Methotrexate Sodium Therapy.
### Importance The long-term implications of hepatotoxic effects in patients with psoriasis…
-
Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease. Key publication
### Background Liver biopsy is considered the gold standard for assessing histologic lesions…
-
External validation of FibroIndex.
-
The diagnostic performance of a simplified blood test (SteatoTest-2) for the prediction of liver steatosis. Key publication
### Background Serum biomarkers of steatosis such as the SteatoTest are recommended for…
-
[SWE elastography in assessment of liver fibrosis]. Review
…using biochemical parameters (Fibrotest) or elastography. Elastography is a new diagnostic tool…
-
Biological markers of liver fibrosis and activity as non-invasive alternatives to liver biopsy in patients with chronic hepatitis C and associated mixed cryoglobulinemia vasculitis.
…non-invasive biological scoring indexes (Fibrotest-Actitest [FT-AT], Forns, APRI, age…
-
Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications.
…For Fibrotest, FibroMeter, and FibroMeter^VCTE^, the decrease in specificity was related…
-
Is it possible to predict HCV-related liver cirrhosis non-invasively through routine laboratory parameters? Review
…tests and a proprietary algorithm (fibrotest) or on routinely available parameters. This…
-
Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.
…A sequential algorithm combining TE with biochemical score (Fibrotest) is proposed. Fifty…
-
Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers. Review
…More expensive tests such as FibroTest or ELF are more specific for…
-
Validation and comparison of indexes for fibrosis and cirrhosis prediction in chronic hepatitis C patients: proposal for a pragmatic approach classification without liver biopsies.
…were included in this paper. FibroTest (FT), aspartate aminotransferase to platelet ratio…
-
Hepatitis B virus genotype G and liver fibrosis progression in chronic hepatitis B and human immunodeficiency virus coinfection.
…When examining averages over time, the rate of FibroTest increase was faster…
-
Commentary: prognostication of chronic hepatitis B - are Fibrotest and Fibroscan the final answers? Authors' reply.
-
PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.
…measured using the non-invasive FibroTest(®). ### Results Advanced liver fibrosis (stage F2…
-
Cost effectiveness of pegylated interferon alpha 2b and ribavirin combination in chronic hepatitis C.
-
Personalized management of cirrhosis by non-invasive tests of liver fibrosis. Review
Owing to the high prevalence of various chronic liver diseases, cirrhosis is…
-
Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Key publication
Liver fibrosis is a common pathway leading to cirrhosis, which is the…
-
Input of serum haptoglobin fucosylation profile in the diagnosis of hepatocellular carcinoma in patients with non-cirrhotic liver disease. Key publication
### Background Haptoglobin bifucosylated tetra-antennary glycan have been identified in patients with…
-
Noninvasive assessment of liver fibrosis in patients with Fontan circulation using transient elastography and biochemical fibrosis markers.
### Objective Studies have shown that patients with failing Fontan circulation may develop…
-
The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis.
…APRI, FIB-4, Hepascore, Fibrotest and FibroMeter. The reference was fibrosis Metavir…
-
Performance of Plasma Biomarkers and Diagnostic Panels for Nonalcoholic Steatohepatitis and Advanced Fibrosis in Patients With Type 2 Diabetes.
…APRI, NAFLD fibrosis score, and FibroTest). ### Results None of the noninvasive tools…
-
Comparison of liver biopsy and noninvasive techniques for liver fibrosis assessment in patients infected with HCV-genotype 4 in Egypt.
…serum markers (APRI, Fib4 and Fibrotest(©)). Patients had to have a LB…
-
Prevalence of liver cirrhosis in individuals with hepatitis B virus infection in sub-Saharan Africa: Systematic review and meta-analysis. Meta Analysis
…APRI score (11 cohorts), and Fibrotest (one cohort). The pooled prevalence of…
-
Nonalcoholic fatty liver disease, nocturnal hypoxia, and endothelial function in patients with sleep apnea.
…blood tests (SteatoTest, NashTest, and FibroTest) were used to evaluate steatosis, nonalcoholic…
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Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: the fibrovic study--ANRS HC02.
…HIV viral load 3.5log. Fibrotest (FT), Hepascore (HS), Fibrometer (FM), SHASTA…
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Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity.
…The sensitivities of the FibroTest and the fibroscan were of 83 and…
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The risk of multiplying diagnostic combinations in the absence of a perfect gold standard for a fibrosis test.
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Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasive.
…algorithm (BA), which cross-check FibroTest with the aspartate aminotransferase-to-platelet…
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Noninvasive diagnosis in alcohol-related liver disease.
…the Enhanced Liver Fibrosis test, FibroTest, and Transient Elastography are the most…
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Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV co-infected patients with chronic hepatitis.
…liver fibrosis as assessed by FibroTest® (r = -0.22; p = 0.008…
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Hepatitis C in 6,865 patients 65 yr or older: a severe and neglected curable disease?
…the usefulness of biochemical markers (Fibrotest-Fibrosure/ActiTest [FT-AT]) in aged…
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Finasteride and methadone use and risk of advanced hepatitis C related liver disease.
### Aim We evaluated the association between two medications that alter bioavailable androgen…
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[Biomarkers for liver fibrosis: advances, advantages and disadvantages]. Review
Liver cirrhosis in Mexico is one of the most important causes of…
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Contribution of the ELFG test in algorithms of non-invasive markers towards the diagnosis of significant fibrosis in chronic hepatitis C.
…Fibrometer®, Fibrotest®, Hepascore®, Apri, ELFG, MP3, Forn's, hyaluronic acid, tissue inhibitor…
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Knowledge and practice regarding the German and the EASL-EASD-EASO NAFLD-guidelines among members of the German Obesity Society.
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Guidelines for the diagnosis of uncomplicated cirrhosis.
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An independent and prospective comparison of two commercial fibrosis marker panels (HCV FibroSURE and FIBROSpect II) during albinterferon alfa-2b combination therapy for chronic hepatitis C.
Noninvasive markers that accurately follow changes in fibrosis may provide alternatives to…
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Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.
…Histological features were assessed invasively by liver biopsy and noninvasively using FibroTest…
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HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.
…Liver fibrosis was estimated by Fibroscan^®^ and Fibrotest^®^ . Liver-related and non…
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Sofosbuvir/velpatasvir in patients with hepatitis C virus genotypes 1-6 and compensated cirrhosis or advanced fibrosis.
…defined by >0.59 on Fibrotest, >9.5 kPa on Fibroscan, or…
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Impact of hepatitis C and liver fibrosis on antiretroviral plasma drug concentrations in HIV-HCV co-infected patients: the HEPADOSE study.
…Among the 73 co-infected patients, 27 had a fibrosis score (Fibrotest…
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Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness. Review
…than other, more expensive non-invasive tests, such as elastography or FibroTest.
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Liver biopsy: the best standard...when everything else fails.
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[The scope of clinical applications of noninvasive methods for the assessment of liver fibrosis results of orginial studies in a multi-field hospital].
…fibrosis are discussed (hepatic elastography, fibrotest, ultrasound dopplerography of portal vessels). Each…
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[Diagnostic value of FibroTest for liver fibrosis in patients with chronic hepatitis B].
### Objective To determine the diagnostic value of FibroTest (FT) for liver fibrosis…
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Defining the Minimum Acceptable Diagnostic Accuracy of Noninvasive Fibrosis Testing in Cirrhosis: A Decision Analytic Modeling Study.
…Combining both decision models, FibroTest plus vibration-controlled transient elastography (VCTE) and…
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Pharmacotherapeutic efficacy on noninvasive fibrosis progression in nonalcoholic fatty liver disease: a systematic review and network meta-analysis. Meta Analysis
…enhanced liver fibrosis (ELF) and FibroTest (FibroSure in the USA). ### Results Forty…
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Non-invasive fibrosis tests to predict complications in compensated post-hepatitis C cirrhosis.
…Actitest/Fibrotest™, Inflameter/Fibrometer™, ELF™ and Fibroscan™ were performed at baseline and…
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Validation of the new 2021 EASL algorithm for the noninvasive diagnosis of advanced fibrosis in NAFLD.
…The FIB4/VCTE/FibroMeter and FIB4/VCTE/Fibrotest algorithms performed similarly, providing…
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[Hepatitis B virus genotypes and evolutionary markers in chronic HBsAG patients in Bujumbura].
…CERBA Laboratory Cergy Pontoise, France. Fibrotest or Fibroscan were used to evaluate…
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Screening for Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Advanced Fibrosis in Diabetology: A Prospective Multicenter Study.
…74 (0.66-0.83); FibroTest, 0.78 (0.72-0.85…
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Non-invasive evaluation of response to obeticholic acid in patients with NASH: Results from the REGENERATE study.
…in Fibrosis-4 (FIB-4), FibroTest, FibroMeter, and FibroScan-AST scores were…
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Haute Autorité de Santé (HAS)
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Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests.
…Fibroscan, Fibrotest, Fibrometer, Hepascore, APRI, PGA, PGAA and hyaluronic acid tests were…
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Noninvasive Assessment of Liver Fibrosis. Key publication Review
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GlycoFibroTest is a highly performant liver fibrosis biomarker derived from DNA sequencer-based serum protein glycomics.
…fibrosis stage equally well as FibroTest (rho = 0.4-0.5 in…
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Liver fibrosis regression and progression during controlled hepatitis B virus infection among HIV-HBV patients treated with tenofovir disoproxil fumarate in France: a prospective cohort study.
…Fibrosis was assessed using the FibroTest® at baseline and every six to…
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Non-invasive diagnosis and follow-up of portal hypertension.
…by LSM <10 kPa, or Fibrotest® ≤0.58, or Fibrometer® ≤0.786…
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Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Review
…The commercially available Enhanced Liver Fibrosis test and FibroTest have comparable performance…
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Noninvasive evaluation of NAFLD. Review
A common clinical concern in patients with NAFLD is whether they have…
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Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods. Review
### Background Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of…
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Impact of steatosis and inflammation definitions on the performance of NASH tests.
### Background And Aim One of the unmet needs in subjects with metabolic…
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Comparison of fatty liver index with noninvasive methods for steatosis detection and quantification.
### Aim To compare noninvasive methods presently used for steatosis detection and quantification…
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Letter: APRI and FIB-4 do not correlate with Fibrosure in the evaluation of liver fibrosis in hepatitis C patients.
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Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection. Review
Chronic hepatitis B virus (HBV) infection is a major cause of liver…
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Late presentation of chronic viral hepatitis for medical care: a consensus definition.
…5, FIB-4 > 3.25, Fibrotest > 0.59 or alternatively transient elastography…
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Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases.
…Liver histology was assessed by the noninvasive tests FibroScan and FibroTest and…
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Hepatitis C virus viremia and low platelet count: a study in a hepatitis B & C endemic area in Taiwan.
…Serum HCV RNA and non-invasive markers of fibrosis (FibroTest) were tested…
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An evaluation of the potential cost-effectiveness of non-invasive testing strategies in the diagnosis of significant liver fibrosis.
### Background And Aim To assess the clinical and economic outcomes of non…
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Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin.
Liver fibrosis and activity indexes were validated in patients infected by hepatitis…
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Effect of antiviral treatment on serum markers of liver fibrosis in HIV-hepatitis C virus-coinfected patients: the Fibrovic 2 Study - ANRS HC02.
…of treatment (week 72; W72). Fibrotest, the Forn's index, age-platelet…
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Retracted: Executive functions in chronic hepatitis C virus infected elderly patients.
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Impact of Non-alcoholic Fatty Liver Disease on long-term cardiovascular events and death in Chronic Obstructive Pulmonary Disease.
Chronic Obstructive Pulmonary Disease (COPD) and Non-Alcoholic Fatty Liver Disease (NAFLD…
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Validation of the Performance of A1HPV6, a Triage Blood Test for the Early Diagnosis and Prognosis of SARS-CoV-2 Infection.
### Background And Aims Apolipoprotein A1 (A1) and haptoglobin (HP) serum levels are…
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Hepatotoxicity of tocilizumab and anakinra in rheumatoid arthritis: management decisions.
…However, FibroTest (Assistance publique - Hôpitaux de Paris, Paris, France) in the latter…
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Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19. Key publication
In patients with non-alcoholic fatty liver disease (NAFLD) with or without…
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Hepatoprotective Effect of Antrodia cinnamomea Mycelium in Patients with Nonalcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial.
### Objective Nonalcoholic steatohepatitis (NASH) has become a prominent liver disease in contemporary…
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Twenty-year protocol liver biopsies: Invasive but useful for the management of liver recipients.
…and 18%, respectively; in VCH, Fibrotest and transient elastography displayed poor discriminative…
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Response to: Impact of Type 2 Diabetes on the Accuracy of Noninvasive Tests of Liver Fibrosis With Resulting Clinical Implications, by Jerome Boursier et al.
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Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis.
### Aim To investigate the diagnostic accuracy of acoustic radiation force impulse (ARFI…
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The use of enzyme results for liver fibrosis evaluation neccessitates standardization.
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Guidelines for the Prevention, Care and Treatment of Persons with Chronic Hepatitis B Infection
These are the first World Health Organization (WHO) guidelines for the prevention…
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FibroSURE as a noninvasive marker of liver fibrosis and inflammation in chronic hepatitis B.
### Background Noninvasive markers of liver fibrosis have not been extensively studied in…
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External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV. Key publication
### Background & Aims The Liver Cancer Risk test algorithm (LCR1-LCR2) is a…
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Glycogenic hepatopathy. Review
…There is no role for noninvasive tests like fibroscan or fibrotest for…
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Acoustic Radiation Force Impulse Imaging for Diagnosis and Monitoring of Liver Fibrosis in Patients with Hepatitis C: A Review of Diagnostic Accuracy, Clinical Effectiveness, Cost-Effectiveness, and Guidelines Review
…moderate to high accuracy for FibroTest, transient elastography (known as FibroScan), and…
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Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes: A Call to Action. Review
Traditionally a disease of hepatologists, nonalcoholic fatty liver disease (NAFLD) has recently…
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Current complications and challenges in nonalcoholic steatohepatitis screening and diagnosis. Review
…Other noninvasive tests such as FibroTest, ELF, Hepascore, FIB-4, NFS, FLI…
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Non-invasive evaluation of liver fibrosis in chronic hepatitis C. Review
…Among the non-invasive methods, Fibrotest and Fibroscan are the most widely…
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Evaluation of liver stiffness measurement by fibroscan as compared to liver biopsy for assessment of hepatic fibrosis in children with chronic hepatitis C.
…as biochemical serum fibrosis markers (Fibrotest, Actitest, AST-to-platelet ratio index…
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Higher serum testosterone is associated with increased risk of advanced hepatitis C-related liver disease in males.
### Unlabelled Males have strikingly increased risk of advanced liver disease. However, the…
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Dietary vitamin E and C intake is inversely associated with the severity of nonalcoholic fatty liver disease.
…significant fibrosis ≥ F1-F2 using FibroTest. Nutritional intake was measured by food…
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Liver stiffness measurement and biochemical markers in Senegalese chronic hepatitis B patients with normal ALT and high viral load.
…For patients with LSM values below 7 kPa, FibroTest® (FT), and Fibrometer…
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A Single Test Combining Blood Markers and Elastography is More Accurate Than Other Fibrosis Tests in the Main Causes of Chronic Liver Diseases.
…0.785 to 0.797, Fibrotest: 0.762, CirrhoMeters: 0.756 to…
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Phase 3, Multicenter Open-Label study to investigate the efficacy of elbasvir and grazoprevir fixed-dose combination for 8 weeks in treatment-naïve, HCV GT1b-infected patients, with non-severe fibrosis.
…Fibroscan^®^ <9.5 kPa and Fibrotest^®^ < 0.59) were enrolled in a…
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Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by FibroScan in non-alcoholic fatty liver disease.
…platelet ratio index (APRI), FIB4, FibroTest, Hepascore, FibroMeter(V2G)). Prognostic accuracy was…
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The new paradigm of hepatitis C therapy: integration of oral therapies into best practices. Review
Emerging data indicate that all-oral antiviral treatments for chronic hepatitis C…
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Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C.
### Background & Aims Coffee or caffeine has been proposed to protect against hepatic…
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Racial differences in the association between adiposity measures and the risk of hepatitis C-related liver disease.
### Background African Americans have lower reported likelihood of hepatitis C virus-related…
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Liver fibrosis in adults with Fontan palliation: Do common screening studies predict disease severity?
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Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy.
### Background And Aim Thrombocytopenia is frequently observed in patients with chronic hepatitis…
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An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver. Key publication
Chronic hepatitis C remains a significant medical and economic burden in Canada…
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Non-invasive assessment of liver fibrosis progression in hepatitis C patients retreated for 96 weeks with antiviral therapy: a randomized study.
### Background The efficacy of a maintenance therapy in non-responder patients with…
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FibroSURE and FibroScan in relation to treatment response in chronic hepatitis C virus.
### Aim To compare histological endpoint assessment using noninvasive alternatives to biopsy during…
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Management of the patient with SVR. Review
In the current era of therapy with direct-acting antiviral (DAAs) drugs…
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EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease.
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Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients.
### Objective Liver biopsy, the gold standard for assessing hepatitis C virus (HCV…
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Prise en charge des personnes infectées par les virus de l’hépatite B ou de l’hépatite C — Rapport de recommandations 2014 Key publication
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Guidelines for the Screening, Care and Treatment of Persons with Hepatitis C Infection Key publication
These are the first guidelines dealing with hepatitis C treatment produced by…
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EASL clinical practical guidelines: management of alcoholic liver disease.
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Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index.
As an alternative to liver biopsy, an index of five biochemical markers…
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Longitudinal assessment of hepatitis C fibrosis progression by collagen and smooth muscle actin morphometry in comparison to serum markers.
### Background Assessment of fibrosis progression in chronic liver disease relies upon non…
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Clinical and genetic definition of serum bilirubin levels for the diagnosis of Gilbert syndrome and hypobilirubinemia.
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Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients.
### Background Hepatic fibrosis is highly prevalent in individuals with Fontan circulation. FibroSure…
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Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography.
### Introduction Recently, a study showed that Controlled Attenuation Parameter (CAP), evaluated with…
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Real-world efficacy and safety of ombitasvir, paritaprevir/r+dasabuvir+ribavirin in genotype 1b patients with hepatitis C virus cirrhosis.
### Background Direct antiviral agents (DAA) showed very good results in terms of…
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Progression of liver fibrosis among injection drug users with chronic hepatitis C.
Although most hepatitis C virus (HCV) infections are acquired by injection drug…
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[Prognosis assessment of alcoholic liver disease: how and why?]. Review
…as biomarker tests (e.g. FibroTest(®) or FibroMetre A(®)) or hepatic elastography…
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.
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EASL Clinical Practice Guidelines: management of hepatitis C virus infection.
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EASL clinical practice guidelines: Management of chronic hepatitis B virus infection.
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